Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Suzy M. Pace"'
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 458:723-732
The Homer protein family allows clustering and/or functional modulation of many proteins from different calcium signalling complexes including those formed by the ryanodine receptor (RyR) Ca(2+) release channel in skeletal muscle and the heart. Homer
Autor:
Peta J. Harvey, Noriaki Ikemoto, Marco G. Casarotto, John D. Lueck, Robert T. Dirksen, Takashi Kimura, Suzy M. Pace, Angela F. Dulhunty
Publikováno v:
Cell Calcium. 45:264-274
Alternative splicing of ASI residues (Ala(3481)-GIn(3485)) in the skeletal muscle ryanodine receptor (RyR1) is developmentally regulated: the residues are present in adult ASI(+)RyR1, but absent in the juvenile ASI(-)RyR1 which is over-expressed in a
Autor:
Kaveenda Samarasinghe, Marco G. Casarotto, Leonard F Arnolda, Padmaja Tummala, Angela F. Dulhunty, Jean Cappello, Philip G. Board, Suzy M. Pace, Dan Liu
Publikováno v:
Biochemical pharmacology. 97(3)
Release of Ca(2+) from the sarcoplasmic reticulum (SR) through the cardiac ryanodine receptor (RyR2) is an essential step in cardiac excitation-contraction coupling. Excess Ca(2+) release due to overactive RyR2 can cause arrhythmia that can lead to c
Autor:
Nicole A. Beard, Francesco Zorzato, Angela F. Dulhunty, Shamaruh Mirza, Dan Liu, Linwei Li, Chris Thekkedam, Esther M. Gallant, Spencer J. Richardson, Suzy M. Pace
Publikováno v:
Journal of Cell Science.
Junctin, a non-catalytic splice variant encoded by the aspartate-β-hydroxylase ( Asph ) gene, is inserted into the membrane of the sarcoplasmic reticulum (SR) Ca 2+ store where it modifies Ca 2+ signalling in the heart and skeletal muscle through it
Autor:
Norbert Wimmer, Angela F. Dulhunty, Yiu-Ngok Chan, Louise Cengia, Jacqui Young, Graham D. Lamb, Peta J. Harvey, Suzy M. Pace, Istvan Toth, Marco G. Casarotto
Publikováno v:
British Journal of Pharmacology. 144:743-754
1 Our aim was to determine whether lipoamino acid conjugation of peptides that are high-affinity activators of ryanodine receptor (RyR) channels would (a) render the peptides membrane permeable, (b) alter their structure or (a) reduce their activity.
Publikováno v:
Biophysical Journal. 80(4):1769-1782
The effect of peptides, corresponding to sequences in the skeletal muscle dihydropyridine receptor II-III loop, on Ca(2+) release from sarcoplasmic reticulum (SR) and on ryanodine receptor (RyR) calcium release channels have been compared in preparat
Autor:
Suzy M. Pace, Marco G. Casarotto, Esther M. Gallant, Derek R. Laver, Angela F. Dulhunty, Suzanne M. Curtis
Publikováno v:
Biophysical Journal. 77(1):189-203
Peptides, corresponding to sequences in the N-terminal region of the skeletal muscle dihydropyridine receptor (DHPR) II-III loop, have been tested on sarcoplasmic reticulum (SR) Ca2+ release and ryanodine receptor (RyR) activity. The peptides were: A
Autor:
Jorgen Mould, Suzanne M. Curtis, Gerard P. Ahern, Suzy M. Pace, Angela F. Dulhunty, Pauline R. Junankar
Publikováno v:
The Journal of Physiology. 514:313-326
1. Ryanodine receptor (RyR) Ca2+ channels in the sarcoplasmic reticulum (SR) of skeletal muscle are regulated by the 12 kDa FK506- (or rapamycin-) binding protein (FKBP12). Rapamycin can also activate RyR channels with FKBP12 removed, suggesting that
Dissection of the inhibition of cardiac ryanodine receptors by human glutathione transferase GSTM2-2
Autor:
Esther M. Gallant, Ruwani Punyakanthi Hewawasam, Dan Liu, Marco G. Casarotto, Philip G. Board, Suzy M. Pace, Angela F. Dulhunty
Publikováno v:
Biochemical pharmacology. 77(7)
The muscle specific glutathione transferase GSTM2-2 inhibits the activity of cardiac ryanodine receptor (RyR2) calcium release channels with high affinity and activates skeletal RyR (RyR1) channels with lower affinity. To determine which overall regi
Autor:
Robert T. Dirksen, Nicole A. Beard, Takashi Kimura, Lan Wei, Angela F. Dulhunty, Suzy M. Pace
The aim of the present study was to examine residues that are variably spliced in the juvenile and adult isoforms of the skeletal-muscle RyR1 (type 1 ryanodine receptor). The juvenile ASI(−) splice variant is less active than the adult ASI(+) varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87745784839ae29a0d356d75596731cc
https://europepmc.org/articles/PMC1698670/
https://europepmc.org/articles/PMC1698670/