Zobrazeno 1 - 10
of 3 518
pro vyhledávání: '"Suzuki coupling"'
Autor:
Jeannes Angelia, Leah Duong, Faye Yun, Anesa Mesic, Cassandra Yuan, Daniel Carr, Siena Gunari, Paula K. Hudson, Christophe Morisseau, Bruce D. Hammock, Ram Kandasamy, Stevan Pecic
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32262- (2024)
Simultaneous inhibition of soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) with a single small molecule represents a novel therapeutic approach in treating inflammatory pain, since both targets are involved in pain and inflammat
Externí odkaz:
https://doaj.org/article/a9debe63a822457898455455adf78d0e
Autor:
V. Parashuram, K. Aruna Kumari, Sai Charitha Mullaguri, Rama Krishna Kancha, Vasantha Mittapelli
Publikováno v:
Results in Chemistry, Vol 8, Iss , Pp 101554- (2024)
Substituted tetrahydropyrido[3,4-d]pyrimidine derivatives (2a-l) have been synthesized through a series of N-substitution, Suzuki coupling, deprotection and condensation reactions. The structure of new compounds was analysed by interpretations of FTI
Externí odkaz:
https://doaj.org/article/bcc18ce10ffd438eac272216c54e7194
Autor:
Lisha K. Poonacha, Rashmi Ramesh, Akshay Ravish, Arunkumar Mohan, Pradeep M. Uppar, Prashant K. Metri, Nanjunda Swamy Shivananju, Santosh L. Gaonkar, Shubha Gopal, Alexey Yu Sukhorukov, Vijay Pandey, Priya Babu Shubha, Basappa Basappa
Publikováno v:
Applied Microbiology, Vol 3, Iss 4, Pp 1214-1228 (2023)
Heterocyclic compounds can specifically regulate bacterial development by targeting specific bacterial enzymes and metabolic pathways. The ESKAPE pathogens are multidrug-resistant and cause nosocomial infections, which is one of the greatest challeng
Externí odkaz:
https://doaj.org/article/9b33de861b99471ab32c0f9333821a16
Autor:
Julia Senkina, Spencer Knapp
Publikováno v:
Molecules, Vol 29, Iss 15, p 3615 (2024)
In order to improve the drug-likeness qualities, the antimalarial endochin-like quinolone (ELQ) scaffold has been modified by replacing the 4-(trifluoromethoxy)phenyl portion with an isoidide unit that is further adjustable by varying the distal O-su
Externí odkaz:
https://doaj.org/article/00edeaaf174f47b69c73daba9889d46e
Autor:
Yingchun Wang, Tomas Opsomer, Flip de Jong, Davy Verhaeghe, Maarten Mulier, Luc Van Meervelt, Mark Van der Auweraer, Wim Dehaen
Publikováno v:
Molecules, Vol 29, Iss 10, p 2229 (2024)
Methyl 4-(1,3a,6a-triazapentalen-3-yl)benzoate (TAP1) shows interesting properties as a small molecule fluorophore. In the search for post-functionalization methods, palladium-catalyzed arylation reactions were demonstrated. Direct CH arylation react
Externí odkaz:
https://doaj.org/article/54ef184dae4c493fa0c0fe899979f3f2
Publikováno v:
Molecules, Vol 29, Iss 9, p 2126 (2024)
In this study, a library of 3,7-di(hetero)aryl-substituted 10-(3-trimethylammoniumpropyl)10H-phenothiazine salts is prepared. These title compounds and their precursors are reversible redox systems with tunable potentials. The Hammett correlation giv
Externí odkaz:
https://doaj.org/article/f0bccf511c164519a6e2abc67fb96290
Autor:
Hossam Nada, Ahmed Elkamhawy, Magda H. Abdellattif, Andrea Angeli, Chang Hoon Lee, Claudiu T. Supuran, Kyeong Lee
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 994-1004 (2022)
Human carbonic anhydrase inhibitors (hCAIs) are a key therapeutic class with a multitude of novel applications such as anticonvulsants, topically acting antiglaucoma, and anticancer drugs. Herein, a new series of 4-anilinoquinazoline-based benzenesul
Externí odkaz:
https://doaj.org/article/23a2051a84c34794a63961386609c546
Autor:
Li, Haibo
The war between human and malaria has never stopped, and the development and application of antimalarial drugs has not eradicated this terrible disease. To fight drug-resistant malaria, many leads have been studied over the years. (1S,3R)-MMV008138 a
Externí odkaz:
http://hdl.handle.net/10919/115359
Publikováno v:
Journal of Materials Research and Technology, Vol 20, Iss , Pp 3905-3917 (2022)
With the advantages of good coordination and degradability, chitosan is an ideal polymeric carrier material for heterogeneous catalysts. In this paper, natural polymer chitosan was toughened and modified by blending with polyvinyl alcohol. Then, chit
Externí odkaz:
https://doaj.org/article/243b3bd98884451f9c3a1283ba96e867
Autor:
Yoshinori Yamanoi
Publikováno v:
Molecules, Vol 29, Iss 3, p 576 (2024)
Bipyridine and related compounds are starting materials or precursors for a variety of valuable substances such as biologically active molecules, ligands for catalysts, photosensitizers, viologens, and supramolecular architectures. Thus, it is import
Externí odkaz:
https://doaj.org/article/d51420e97b454380846ce16b0239e778