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Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors

Autor: Kunihiko Minakata, Hiroyuki Moriyama, Muneaki Hashimoto, Kuniaki Seyama, Takeshi Nara, Kazuto Nishio, Fumiyuki Takahashi, Kazuhisa Takahashi, Suzu Yae, Fariz Nurwidya, Fumiaki Koizumi, Akiko Murakami, Ken Tajima

Publikováno v: Cancer Sci

Somatic mutations in the epidermal growth factor receptor (EGFR) gene, such as exon 19 deletion mutations, are important factors in determining therapeutic responses to gefitinib in non‐small‐cell lung cancer (NSCLC). However, some patients have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7efba6cb8da79a817f68a8aaadf12f
https://doi.org/10.1111/j.1349-7006.2012.02408.x

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Effect of Continuation of Chemotherapy on Quality of Life in Elderly Patients with Lung Cancer -Comparison with That in Younger Patients

Autor: Suzu Yae, Kazuhisa Takahashi, Ryo Koyama, Kayo Miura, Akiko Murakami

Publikováno v: Juntendo Medical Journal. 58:506-511

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::492df9a55402dea69fabc89ee8cc68b2
https://doi.org/10.14789/pjmj.58.506

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Brief psychotic disorder mimicking the symptoms of cerebrovascular attack evoked by symptoms that symbolized death in a patient with terminal stage stomach cancer: Case report and review of the literature

Autor: Yasuhiro Mizuno, Suzu Yae, Chiaki Kawanishi, Motonori Sairenji, Masanari Onose, Shigeko Okuno, Hideki Onishi

Publikováno v: Palliative and Supportive Care. 4:87-89

Objective: We report here a terminally ill patient with stomach cancer who developed a brief psychotic disorder mimicking cerebrovascular attack after a short episode of nasal bleeding. Close examination of the patient revealed that nasal bleeding wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1cec48bf93626b6bf004b3bd1e3aa48
https://doi.org/10.1017/s147895150606010x

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Hochuekkito (TJ-41), a Kampo Formula, Ameliorates Cachexia Induced by Colon 26 Adenocarcinoma in Mice

Autor: Suzu Yae, Hiroyuki Kobayashi, Akiko Murakami, Fariz Nurwidya, Mayumi Tamada, Kunihiko Minakata, Kazuhisa Takahashi, Rika Tsukada, Motoyasu Kato, Kengo Koike, Kuniaki Seyama, Toshifumi Yae, Fumiyuki Takahashi, Momoko Yoshikawa, Takuji Yamaguchi

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2012 (2012)

Cachexia, a major cause of cancer-related death, is characterized by depletion of muscle and fat tissues, anorexia, asthenia, and hypoglycemia. Recent studies indicate that secretions of proinflammatory cytokines such as interleukin-6 (IL-6) play a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4292598828e822ffe6b355fb638fe28d
https://pubmed.ncbi.nlm.nih.gov/23326296

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Genetic Heterogeneity Of Epidermal Growth Factor Receptor And Hypoxia Are Important Factors In Resistance To Gefitinib In Non-Small Cell Lung Cancer

Autor: Keiko Muraki, Toshifumi Yae, Rina Ohashi, Fumiyuki Takahashi, Fariz Nurwidya, Ken Tajima, Ryo Koyama, Kuniaki Seyama, Suzu Yae, Kunihiko Minakata, Takanori Mori, Takehito Shukuya, Akiko Murakami, Kazuhisa Takahashi

Publikováno v: C66. MOLECULAR TARGETS FOR THERAPEUTIC DEVELOPMENT IN LUNG CANCER.

Somatic mutations in epidermal growth factor receptor (EGFR) gene, such as exon 19 deletion mutation, are important factors Rationale; to determine therapeutic response to gefitinib in non-small cell lung cancer (NSCLC). However, there are patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04b25273bc04112f2fbbf16aea7bcd3c
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5087

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Development of Wernicke encephalopathy in a terminally ill cancer patient consuming an adequate diet: a case report and review of the literature

Autor: Chiaki Kawanishi, Suzu Yae, Hideki Onishi, Shigeko Okuno

Publikováno v: Palliativesupportive care. 3(4)

Malignancy-associated primary thiamine deficiency has been documented in several experimental tumors, clinical case reports, and in patients with fast growing malignancies. We report a terminally ill cancer patient who developed delirium. Close exami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f312f75157d11819bd0c66b8b176c7a
https://pubmed.ncbi.nlm.nih.gov/17039989

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Spouse caregivers of terminally-ill cancer patients as cancer patients: a pilot study in a palliative care unit

Autor: Mizuho Ito, Chiaki Kawanishi, Masanari Onose, Hideki Onishi, Yasuhiro Mizuno, Suzu Yae, Shigeko Okuno, Hideyuki Saito

Publikováno v: Palliativesupportive care. 3(2)

Objective: It is known that families of terminally-ill cancer patients show levels of emotional and functional disruption and are called “second order patients,” however, little is actually known about the health problems of family members, espec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543ce61893642619460d93a49340ce1a
https://pubmed.ncbi.nlm.nih.gov/16594432

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