Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Suziane Raymundo"'
Autor:
Suziane Raymundo, Victória Vendramini Müller, Mariane Tegner, Andiara Artmann, Natália B. Andriguetti, Gilberto Schwartsmann, Rafael Linden, Marina V. Antunes
Publikováno v:
Química Nova, Vol 43, Iss 4, Pp 474-479
A highly sensitive ultra-performance liquid chromatography tandem mass spectrometry method for the determination of Docetaxel and metabolites (M1+M3) in human plasma samples was developed and validated. The method employs a liquid-liquid extraction a
Externí odkaz:
https://doaj.org/article/682a33a605874678b406ae131a2e4de2
Autor:
Gilberto Schwartsmann, Suziane Raymundo, Marina Venzon Antunes, Andiara do Carmo Artmann, Victória Vendramini Müller, Mariane Tegner, Natália Bordin Andriguetti, Rafael Linden
Publikováno v:
Química Nova v.43 n.4 2020
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Vol 43, Iss 4, Pp 474-479
Química Nova, Volume: 43, Issue: 4, Pages: 474-479, Published: 10 JUN 2020
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Vol 43, Iss 4, Pp 474-479
Química Nova, Volume: 43, Issue: 4, Pages: 474-479, Published: 10 JUN 2020
A highly sensitive ultra-performance liquid chromatography tandem mass spectrometry method for the determination of Docetaxel and metabolites (M1+M3) in human plasma samples was developed and validated. The method employs a liquid-liquid extraction a
Autor:
Gustavo Vasconcelos Alves, Olavo José Vicente Neto, Gilberto Schwartsmann, Suziane Raymundo, Roberta Zilles Hahn, Maria Alice Franzoi, Andiara do Carmo Artmann, Rafael Linden, Mariane Tegner, Victória Vendramini Müller, Marina Venzon Antunes
Publikováno v:
Clinical Biochemistry. 56:18-25
OBJECTIVE to evaluate plasma and salivary uracil (U) to dihydrouracil (UH2) ratios as tools for predicting 5-fluorouracil systemic exposure and drug-related severe toxicity, and clinically validate the use of dried saliva spots (DSS) as an alternativ
Autor:
Ramon Magalhães Mendonça Vilela, Rafael Linden, Gilberto Schwartsmann, Maria Alice Franzoi, Mariane Tegner, Marina Venzon Antunes, Andiara do Carmo Artmann, Suziane Raymundo, H.M. Kluck, Victória Vendramini Müller, Natália Bordin Andriguetti
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 157
In this study, a LC–MS/MS method for the measurement of docetaxel in Dried Blood Spots (DBS) samples was developed and validated. Docetaxel was extracted from 8 mm DBS punch with a mixture of methanol and acetonitrile (9:1, v/v). The chromatographi
Autor:
Helena Moreira Klück, Kelly Francisco da Cunha, Gilberto Schwartsmann, Roberta Zilles Hahn, Ramon Magalhães Mendonça Vilela, Lilian de Lima Feltraco Lizot, José Luiz Costa, Suziane Raymundo, Natália Bordin Andriguetti, Marina Venzon Antunes, Rafael Linden
Publikováno v:
Clinical biochemistry. 54
Background Paclitaxel (PCT) is a chemotherapeutic drug widely used for the treatment of several types of tumors, and its use is associated with severe adverse events, mainly neurologic and hematopoietic toxicities. The relation between systemic expos
Autor:
Marina Venzon Antunes, Suziane Raymundo, Simone Gasparin Verza, Magda Susana Perassolo, Rafael Linden, Natália Bordin Andriguetti, Edna Sayuri Suyenaga
Publikováno v:
Current medicinal chemistry. 24(33)
BACKGROUND The taxane drugs paclitaxel and docetaxel, widely used on cancer chemotherapy, are currently dosed mainly based on body-surface area. This approach is associated with wide interindividual variability in drug exposure, leading to suboptimal
Autor:
Suziane Raymundo, Jorge Villanova Biazús, Gustavo Gössling, José Antônio Crespo Cavalheiro, Vanessa de Oliveira, Gilberto Schwartsmann, Dilana Elisabeth Staudt, Rafael Linden, Rafaela Pirolli, Marina Venzon Antunes, Daniela Dornelles Rosa
Publikováno v:
Clinical Biochemistry. 47:1084-1090
Objective To develop and validate a method for determination of dextromethorphan (DMT) and dextrorphan (DTP) in plasma samples using HPLC-FL and to apply it to CYP2D6 phenotyping of a population from the South of Brazil. Methods Samples were prepared
Autor:
Andrés Fernando Andrade Galarza, Gilberto Schwartsmann, Suziane Raymundo, Fernando Rosado Spilki, Anne Caroline Cezimbra da Silva, Rafael Linden, Rodrigo Staggemeier, Marina Venzon Antunes, Roberta Zilles Hahn
Publikováno v:
Clinical biochemistry. 49(16-17)
Objective The aim of this study was to evaluate the use of plasma and saliva uracil (U) to dihydrouracil (UH2) metabolic ratio and DPYD genotyping, as a means to identify patients with dihydropyrimidine dehydrogenase (DPD) deficiency and fluoropyrimi
Autor:
Victória Vendramini Müller, Marina Venzon Antunes, Andiara do Carmo Artmann, Gustavo Vasconcelos Alves, Mariane Tegner, Suziane Raymundo, Rafael Linden, Maria Alice Franzoi, Gilberto Schwartsmann, Olavo José Vicente Neto, Roberta Zilles Hahn
Publikováno v:
Journal of Clinical Oncology. 36:e14563-e14563
e14563Background: This project aimed to evaluate plasma and salivary uracil (U) to dihydrouracil (UH2) ratios as tools for predicting 5-Fluorouracil systemic exposure and drug-related severe toxici...
Autor:
Fabiola Reginato, Sandrine Comparsi Wagner, Rafael Linden, Natalia Vieira, Vanessa Suñé Mattevi, Suziane Raymundo, Marina Venzon Antunes, Renata Leite, Laura Fogliatto, Marcelo Capra
Publikováno v:
Bioanalysis. 7(16)
Background: Imatinib (IM) is widely used in treatment of chronic myeloid leukemia with target trough plasma concentrations above 1000 ng ml-1. DBS can increase access to IM therapeutic drug monitoring. Results: IM was measured in the range 50–4000