Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Suzee E, Lee"'
Autor:
Sylvia Mihailescu, Quinn Hlava, Philip A. Cook, Maria Luisa Mandelli, Suzee E. Lee, Bradley F. Boeve, Bradford C. Dickerson, Maria Luisa Gorno-Tempini, Emily Rogalski, Murray Grossman, James Gee, Corey T. McMillan, Christopher A. Olm
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionFrontotemporal lobar degeneration (FTLD) is associated with FTLD due to tau (FTLD-tau) or TDP (FTLD-TDP) inclusions found at autopsy. Arterial Spin Labeling (ASL) MRI is often acquired in the same session as a structural T1-weighted image
Externí odkaz:
https://doaj.org/article/df95660fbdbd499fb260b1ca808d1d37
Autor:
Daniel W. Sirkis, Caroline Warly Solsberg, Taylor P. Johnson, Luke W. Bonham, Virginia E. Sturm, Suzee E. Lee, Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, Bruce L. Miller, Ethan G. Geier, Jennifer S. Yokoyama
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-22 (2023)
Abstract Background Emerging evidence from mouse models is beginning to elucidate the brain’s immune response to tau pathology, but little is known about the nature of this response in humans. In addition, it remains unclear to what extent tau path
Externí odkaz:
https://doaj.org/article/593d8cbdd12d4eee9bf2368860ac1c9f
Autor:
Iris J. Broce, Daniel W. Sirkis, Ryan M. Nillo, Luke W. Bonham, Suzee E. Lee, Bruce L. Miller, Patricia A. Castruita, Virginia E. Sturm, Leo S. Sugrue, Rahul S. Desikan, Jennifer S. Yokoyama
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionA hexanucleotide repeat expansion (HRE) intronic to chromosome 9 open reading frame 72 (C9orf72) is recognized as the most common genetic cause of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and ALS-FTD. Identifyin
Externí odkaz:
https://doaj.org/article/b13a9c462df547a2b3c345568ced924f
Autor:
Ashlin R. K. Roy, Fate Noohi, Nathaniel A. Morris, Peter Ljubenkov, Hilary Heuer, Jamie Fong, Matthew Hall, Argentina Lario Lago, Katherine P. Rankin, Bruce L. Miller, Adam L. Boxer, Howard J. Rosen, William W. Seeley, David C. Perry, Jennifer S. Yokoyama, Suzee E. Lee, Virginia E. Sturm
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103649- (2024)
Diminished basal parasympathetic nervous system activity is a feature of frontotemporal dementia that relates to left frontoinsula dysfunction and empathy impairment. Individuals with a pathogenic expansion of the hexanucleotide repeat in chromosome
Externí odkaz:
https://doaj.org/article/3c9d5becbbde4415997ecc5f53eb7962
Autor:
Celeste M. Karch, Aimee W. Kao, Anna Karydas, Khadijah Onanuga, Rita Martinez, Andrea Argouarch, Chao Wang, Cindy Huang, Peter Dongmin Sohn, Kathryn R. Bowles, Salvatore Spina, M. Catarina Silva, Jacob A. Marsh, Simon Hsu, Derian A. Pugh, Nupur Ghoshal, Joanne Norton, Yadong Huang, Suzee E. Lee, William W. Seeley, Panagiotis Theofilas, Lea T. Grinberg, Fermin Moreno, Kathryn McIlroy, Bradley F. Boeve, Nigel J. Cairns, John F. Crary, Stephen J. Haggarty, Justin K. Ichida, Kenneth S. Kosik, Bruce L. Miller, Li Gan, Alison M. Goate, Sally Temple, Carolina Alquezar, Kathryn Bowles, David Butler, Israel Hernandez, Valerie Hennes, Martin Kampmann
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 939-955 (2019)
Summary: Primary tauopathies are characterized neuropathologically by inclusions containing abnormal forms of the microtubule-associated protein tau (MAPT) and clinically by diverse neuropsychiatric, cognitive, and motor impairments. Autosomal domina
Externí odkaz:
https://doaj.org/article/598d132842794126ace928eb080d817b
Autor:
Richard M. Tsai, Alexandre Bejanin, Orit Lesman-Segev, Renaud LaJoie, Adrienne Visani, Viktoriya Bourakova, James P. O’Neil, Mustafa Janabi, Suzanne Baker, Suzee E. Lee, David C. Perry, Lynn Bajorek, Anna Karydas, Salvatore Spina, Lea T. Grinberg, William W. Seeley, Eliana M. Ramos, Giovanni Coppola, Maria Luisa Gorno-Tempini, Bruce L. Miller, Howard J. Rosen, William Jagust, Adam L. Boxer, Gil D. Rabinovici
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-18 (2019)
Abstract Background The tau positron emission tomography (PET) ligand 18F-flortaucipir binds to paired helical filaments of tau in aging and Alzheimer’s disease (AD), but its utility in detecting tau aggregates in frontotemporal dementia (FTD) is u
Externí odkaz:
https://doaj.org/article/1733aae59d224cd5a72a1f4f4fc79342
Publikováno v:
Neurobiology of Disease, Vol 145, Iss , Pp 105063- (2020)
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) have a strong clinical, genetic and pathological overlap. This review focuses on the current understanding of structural, functional and molecular neuroimaging signatures of geneti
Externí odkaz:
https://doaj.org/article/001d535126164c64a2c90a3d11b421f7
Autor:
Luke W. Bonham, Ethan G. Geier, Daniel W. Sirkis, Josiah K. Leong, Eliana Marisa Ramos, Qing Wang, Anna Karydas, Suzee E. Lee, Virginia E. Sturm, Russell P. Sawyer, Adit Friedberg, Justin K. Ichida, Aaron D. Gitler, Leo Sugrue, Michael Cordingley, Walter Bee, Eckard Weber, Joel H. Kramer, Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, John Ravits, Bruce L. Miller, Jennifer S. Yokoyama
Publikováno v:
The Journal of Neuroscience. 43:333-345
Hexanucleotide repeat expansion (HRE) withinC9orf72is the most common genetic cause of frontotemporal dementia (FTD). Thalamic atrophy occurs in both sporadic and familial FTD but is thought to distinctly affect HRE carriers. Separately, emerging evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cfdbe4480f987d12b252f86e4c33446
https://doi.org/10.1523/jneurosci.1448-22.2022
https://doi.org/10.1523/jneurosci.1448-22.2022
Autor:
Jesse A. Brown, Alice Y. Hua, Andrew Trujillo, Suneth Attygalle, Richard J. Binney, Salvatore Spina, Suzee E. Lee, Joel H. Kramer, Bruce L. Miller, Howard J. Rosen, Adam L. Boxer, William W. Seeley
Publikováno v:
NeuroImage: Clinical, Vol 16, Iss , Pp 564-574 (2017)
Progressive supranuclear palsy syndrome (PSP-S) results from neurodegeneration within a network of brainstem, subcortical, frontal and parietal cortical brain regions. It is unclear how network dysfunction progresses and relates to longitudinal atrop
Externí odkaz:
https://doaj.org/article/9e5304d85b25450c90e75678e5fedd3c
Autor:
Suzee E. Lee, Ana C. Sias, Maria Luisa Mandelli, Jesse A. Brown, Alainna B. Brown, Anna M. Khazenzon, Anna A. Vidovszky, Theodore P. Zanto, Anna M. Karydas, Mochtar Pribadi, Deepika Dokuru, Giovanni Coppola, Dan H. Geschwind, Rosa Rademakers, Maria Luisa Gorno-Tempini, Howard J. Rosen, Bruce L. Miller, William W. Seeley
Publikováno v:
NeuroImage: Clinical, Vol 14, Iss C, Pp 286-297 (2017)
Hexanucleotide repeat expansions in C9ORF72 are the most common known genetic cause of familial and sporadic frontotemporal dementia and amyotrophic lateral sclerosis. Previous work has shown that patients with behavioral variant frontotemporal demen
Externí odkaz:
https://doaj.org/article/3fe03fa3169d4cfea2dead08352fe02d