Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Suze A. Jansen"'
Autor:
Suze A. Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Cynthia L. Frederiks, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E.S. Nieuwenhuis, Alan M. Hanash, Enric Mocholi, Paul J. Coffer, Caroline A. Lindemans
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110072- (2024)
Summary: The intestine is vulnerable to chemotherapy-induced damage due to the high rate of intestinal epithelial cell (IEC) proliferation. We have developed a human intestinal organoid-based 3D model system to study the direct effect of chemotherapy
Externí odkaz:
https://doaj.org/article/b237740e0ce446bdbb6f4231e7e5bc68
Autor:
Marco Calafiore, Ya-Yuan Fu, Paola Vinci, Viktor Arnhold, Winston Y. Chang, Suze A. Jansen, Anastasiya Egorova, Shuichiro Takashima, Jason Kuttiyara, Takahiro Ito, Jonathan Serody, Susumu Nakae, Heth Turnquist, Johan van Es, Hans Clevers, Caroline A. Lindemans, Bruce R. Blazar, Alan M. Hanash
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Intestinal stem cells (ISCs) maintain the epithelial lining of the intestines, but mechanisms regulating ISCs and their niche after damage remain poorly understood. Utilizing radiation injury to model intestinal pathology, we report here tha
Externí odkaz:
https://doaj.org/article/9b625ca7598346a7aef6d804ad1b9d63
Autor:
Suze A. Jansen, Wouter Nijhuis, Helen L. Leavis, Annelies Riezebos-Brilman, Caroline A. Lindemans, Rob Schuurman
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Pediatric allogeneic hematopoietic stem cell transplantation (HSCT) patients often suffer from gastro-intestinal (GI) disease caused by viruses, Graft-versus-Host Disease (GVHD) or a combination of the two. Currently, the GI eukaryotic virome of HSCT
Externí odkaz:
https://doaj.org/article/2f46784458c9470d82e754d05edbbc63
Publikováno v:
Mucosal Immunology. 15:605-619
Chemotherapy-Induced Intestinal Epithelial Damage Can Attract T Cells and Modulate T Cell Activation
Autor:
Alessandro Cutilli, Suze A. Jansen, Marliek Hoesel, Coco C de Koning, Stefan Nierkens, Alan M. Hanash, Enric Mocholi, Paul James Coffer, Caroline Ariane Lindemans
Publikováno v:
Transplantation and Cellular Therapy. 29:S244
Autor:
Kristina Russu, Christian Körner, Mirjam E Belderbos, Kimberly J. Möller, Suze A. Jansen, Mareike Ohms, Annika Niehrs, Ingo Königs, Anja Ehrhardt, Johannes M. Jung, Lucy Wegner, Martin E. Baumdick, Helga Hofmann-Sieber, Thomas Dobner, Marc Lütgehetmann, Madeleine J. Bunders, Wilhelm Ching, Marcus Altfeld, Angelique Hölzemer, Kevin Duisters, Caroline A. Lindemans, Sven Peine, Tobias Koyro, Wenli Zhang, Daniel Perez, Jens B. Bosse, Eric Spierings, Konrad Reinshagen
Publikováno v:
Science immunology. 6(63)
Human adenoviruses (HAdVs) are a major cause for disease in children, in particular after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Currently, effective therapies for HAdV infections in immunocompromised hosts are lacking. To de
Autor:
Anne B. Verbeek, Suze A. Jansen, Erik G.J. von Asmuth, Arjan C. Lankester, Dorine Bresters, Marc Bierings, Alexander B. Mohseny, Caroline A. Lindemans, Emilie P. Buddingh
Publikováno v:
Transplantation and Cellular Therapy, 28(9). ELSEVIER SCIENCE INC
Steroid-refractory acute graft-versus-host disease (SR-aGvHD) is a severe complication in pediatric allogeneic hematopoietic stem cell transplantation (HSCT). We aimed to assess clinical course and outcomes of pediatric SR-aGvHD. We performed a retro
Autor:
Suze A. Jansen, Anne B. Verbeek, Erik G.J. von Asmuth, Konradin F. Muskens, Emilie P. Buddingh, Caroline A. Lindemans
Publikováno v:
Transplantation and Cellular Therapy. 28:S288-S289
Autor:
Viktor Arnhold, Suze A. Jansen, Winston Chang, Govindarajan Thangavelu, Paola Vinci, Shuichiro Takashima, Anastasiya Egorova, Jason Kuttiyara, Chen Liu, Marco Calafiore, Bruce R. Blazar, Caroline A. Lindemans, Alan M. Hanash
Publikováno v:
Transplantation and Cellular Therapy. 28:S284
Autor:
Daniel J. Chandra, Ross L. Levine, Caroline A. Lindemans, Noah F. Shroyer, Sean M. Devlin, S. Middendorp, Joris Bos, Margaret O'Connor, Alan M. Hanash, M. Kleppe, Shuichiro Takashima, Anastasiya Egorova, Paola Vinci, Chen Liu, Maria Laura Martin, Suze A. Jansen, Anna Mertelsmann, Jason Kuttiyara, Yuan-Hung Lo, Richard Kolesnick, Ya-Yuan Fu, Emily H. Cheng, Marco Calafiore
Publikováno v:
Science Immunology. 4
Despite the importance of intestinal stem cells (ISCs) for epithelial maintenance, there is limited understanding of how immune-mediated damage affects ISCs and their niche. We found that stem cell compartment injury is a shared feature of both allor