An industrialized diet as a determinant of methylation in the 1F region of the NR3C1 gene promoter

Autor: Tamires dos Santos Vieira, Flávia Vitorino Freitas, Luiz Cláudio Barreto Silva Neto, Aline Ribeiro Borçoi, Suzanny Oliveira Mendes, Amanda Sgrancio Olinda, Ivana Alece Arantes Moreno, Bárbara Risse Quaioto, Marcele Lorentz Mattos de Souza, Wagner Miranda Barbosa, Juliana Krüger Arpini, Bruna Pereira Sorroche, Julia de Assis Pinheiro, Anderson Barros Archanjo, Joaquim Gasparini dos Santos, Lidia Maria Rebolho Batista Arantes, Daniela Rodrigues de Oliveira, Adriana Madeira Alvares da Silva

Publikováno v: Frontiers in Nutrition, Vol 11 (2024)

BackgroundDietary composition can modify gene expression, favoring the development of chronic diseases via epigenetic mechanisms.ObjectiveOur study aimed to investigate the relationship between dietary patterns and NR3C1 gene methylation in users of

Externí odkaz: https://doaj.org/article/662eaf405ade45c38dfe32de3420c239

Alcohol consumption, depression, overweight and cortisol levels as determining factors for NR3C1 gene methylation

Autor: Júlia de Assis Pinheiro, Flávia Vitorino Freitas, Aline Ribeiro Borçoi, Suzanny Oliveira Mendes, Catarine Lima Conti, Juliana Krüger Arpini, Tamires dos Santos Vieira, Rafael Assis de Souza, Dirceu Pereira dos Santos, Wagner Miranda Barbosa, Anderson Barros Archanjo, Mayara Mota de Oliveira, Joaquim Gasparini dos Santos, Bruna Pereira Sorroche, José Claudio Casali-da-Rocha, Leonardo Oliveira Trivilin, Elizeu Batista Borloti, Iuri Drumond Louro, Lidia Maria Rebolho Batista Arantes, Adriana Madeira Alvares-da-Silva

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract The NR3C1 glucocorticoid receptor (GR) gene is a component of the stress response system, which can be regulated by epigenetic mechanisms. NR3C1 methylation has been associated with trauma and mental issues, including depression, post-trauma

Externí odkaz: https://doaj.org/article/3ee46a3fb1d94e37bf89418044be54f7

Tobacco use modify exon IV BDNF gene methylation levels in depression

Autor: Bárbara Risse Quaioto, Aline Ribeiro Borçoi, Suzanny Oliveira Mendes, Paola Cerbino Doblas, Tamires dos Santos Vieira, Ivana Alece Arantes Moreno, Joaquim Gasparini dos Santos, André Willian Hollais, Amanda Sgrancio Olinda, Marcele Lorentz Mattos de Souza, Flávia Vitorino Freitas, Júlia Assis Pinheiro, Ester Ribeiro Cunha, Bruna Pereira Sorroche, Lídia Maria Rebolho Batista Arantes, Adriana Madeira Álvares-da-Silva

Publikováno v: Journal of Psychiatric Research. 159:240-248

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df5d5c9b76ee50459c28a82c8bf4c9e2
https://doi.org/10.1016/j.jpsychires.2023.01.038

JMJD1A, H3K9me1, H3K9me2 and ADM expression as prognostic markers in oral and oropharyngeal squamous cell carcinoma.

Autor: Lucas de Lima Maia, Gabriela Tonini Peterle, Marcelo Dos Santos, Leonardo Oliveira Trivilin, Suzanny Oliveira Mendes, Mayara Mota de Oliveira, Joaquim Gasparini Dos Santos, Elaine Stur, Lidiane Pignaton Agostini, Cinthia Vidal Monteiro da Silva Couto, Juliana Dalbó, Aricia Leone Evangelista Monteiro de Assis, Anderson Barros Archanjo, Ana Maria Da Cunha Mercante, Rossana Veronica Mendoza Lopez, Fábio Daumas Nunes, Marcos Brasilino de Carvalho, Eloiza Helena Tajara, Iúri Drumond Louro, Adriana Madeira Álvares-da-Silva

Publikováno v: PLoS ONE, Vol 13, Iss 3, p e0194884 (2018)

Jumonji Domain-Containing 1A (JMJD1A) protein promotes demethylation of histones, especially at lysin-9 of di-methylated histone H3 (H3K9me2) or mono-methylated (H3K9me1). Increased levels of H3 histone methylation at lysin-9 (H3K9) is related to tum

Externí odkaz: https://doaj.org/article/ee562569ed92474094c5a8f5cf7d6f06

Elemental characterization of oral cavity squamous cell carcinoma and its relationship with smoking, prognosis and survival

Autor: Arícia Leone Evangelista Monteiro de Assis, Marcelo dos Santos, Anderson Barros Archanjo, Mayara Mota de Oliveira, Marcos Brasilino de Carvalho, Lucas de Lima Maia, Christiano Jorge Gomes Pinheiro, Kelly Cristina Saito, Leonardo Oliveira Trivilin, Suzanny Oliveira Mendes, Rafael Pereira de Souza, Edna Teruko Kimura, Aline Ribeiro Borçoi, Rafael de Cicco, Breno Valentim Nogueira, Adriana Madeira Álvares-da-Silva, Eloiza H. Tajara, Fábio Daumas Nunes

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da UFRN
Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
Scientific Reports

Oral cancer squamous cell carcinoma (OCSCC) mainly affects individuals aged between 50 and 70 years who consume tobacco and alcohol. Tobacco smoke contains hundreds of known toxic and carcinogenic molecules, and a few studies have sought to verify th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a952caa9bef4917796f81db34bab2a
http://link.springer.com/article/10.1038/s41598-020-67270-5