Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Suzanne Schubbert"'
Autor:
Rajbharan Yadav, Suzanne Schubbert, Patrick G. Holder, Eugene Y. Chiang, Nargess Kiabi, Liz Bogaert, Irene Leung, Rumana Rashid, Kendra N. Avery, Christine Bonzon, John R. Desjarlais, Shomyseh Sanjabi, Amy Sharma, Michelle Lepherd, Amy Shelton, Pam Chan, Yanqiu Liu, Louis Joslyn, Iraj Hosseini, Eric G. Stefanich, Amrita V. Kamath, Matthew J. Bernett, Vittal Shivva
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionInterleukin 15 (IL-15) is a potential anticancer agent and numerous engineered IL-15 agonists are currently under clinical investigation. Selective targeting of IL-15 to specific lymphocytes may enhance therapeutic effects while helping t
Externí odkaz:
https://doaj.org/article/31030b79b4034614806d2f9e04a075ba
Autor:
Gregory Moore, Lukasz Ochyl, Christine Bonzon, Seung Chu, Rumana Rashid, John Desjarlais, Kendra Avery, Suzanne Schubbert, Erik Pong, Alex Nisthal, James Ernst
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/57dc984eb5824ed799cca2f897161d6b
Autor:
Hong Wu, James Bradner, Wei Guo, Consuelo Garcia, Harrison Chen, Anjelica Cardenas, Suzanne Schubbert
Primary human pediatric T-ALL samples show elevated levels of phospho-AKT.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b6dbb7b03cc5144327d064d286771f
https://doi.org/10.1158/0008-5472.22404383.v1
https://doi.org/10.1158/0008-5472.22404383.v1
Autor:
Hong Wu, James Bradner, Wei Guo, Consuelo Garcia, Harrison Chen, Anjelica Cardenas, Suzanne Schubbert
Disease relapse remains the major clinical challenge in treating T-cell acute lymphoblastic leukemia (T-ALL), particularly those with PTEN loss. We hypothesized that leukemia-initiating cells (LIC) are responsible for T-ALL development and treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054e1c344052355904cba567f536117f
https://doi.org/10.1158/0008-5472.c.6506591
https://doi.org/10.1158/0008-5472.c.6506591
Autor:
Hong Wu, James Bradner, Wei Guo, Consuelo Garcia, Harrison Chen, Anjelica Cardenas, Suzanne Schubbert
Pten null T-ALL blasts show lower levels of phospho-AKT in response to JQ1 in comparison to LICs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131d86ce28cf15f998f523889a4a74a1
https://doi.org/10.1158/0008-5472.22404380
https://doi.org/10.1158/0008-5472.22404380
Autor:
Hong Wu, James Bradner, Wei Guo, Consuelo Garcia, Harrison Chen, Anjelica Cardenas, Suzanne Schubbert
Testing the efficacy of combination therapy using small molecules to reduce Pten null leukemia burden and LICs in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addb320c8923d2368c6ac73ddca6ee5d
https://doi.org/10.1158/0008-5472.22404395
https://doi.org/10.1158/0008-5472.22404395
Autor:
Hong Wu, James Bradner, Wei Guo, Consuelo Garcia, Harrison Chen, Anjelica Cardenas, Suzanne Schubbert
Supplementary Materials and Methods, Supplementary Figure Legends, and Characteristics of primary human pediatric T-ALL samples (Supplementary Table S1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c0706ca2b5e58176e341ffd35105fb
https://doi.org/10.1158/0008-5472.22404374.v1
https://doi.org/10.1158/0008-5472.22404374.v1
Autor:
Hong Wu, James Bradner, Wei Guo, Consuelo Garcia, Harrison Chen, Anjelica Cardenas, Suzanne Schubbert
Sensitivity of primary human pediatric T-ALL cells to rapamycin and JQ1 in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b6a956118368daf0da8291e818bd4b
https://doi.org/10.1158/0008-5472.22404386
https://doi.org/10.1158/0008-5472.22404386
Autor:
Hong Wu, James Bradner, Wei Guo, Consuelo Garcia, Harrison Chen, Anjelica Cardenas, Suzanne Schubbert
DN thymocytes (DN3 and DN4) show highest levels of c-Myc in comparison to DP and SP populations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4ed66b588d5f8a894a1f61b829276a
https://doi.org/10.1158/0008-5472.22404377.v1
https://doi.org/10.1158/0008-5472.22404377.v1
Autor:
Hong Wu, James Bradner, Wei Guo, Consuelo Garcia, Harrison Chen, Anjelica Cardenas, Suzanne Schubbert
Cellular and biochemical effects of JQ1 in T-ALL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9bf39924315e9128b41a999c767e1e
https://doi.org/10.1158/0008-5472.22404389
https://doi.org/10.1158/0008-5472.22404389