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Autor:
Suzanne S. Alfano, Ramin Naim, Gregor Bran, Karl Hörmann, Christiane Bayerl, Ray C. Chang, Frank Riedel, Haneen Sadick
Publikováno v:
Regulatory Peptides. 130:75-80
The transforming growth factor (TGF)-beta 1 is known to have pro- and anti-angiogenic actions. Hepatocyte growth factor/scatter factor (HGF/SF) antagonizes TGF-beta1 by stabilizing SMAD transcriptional co-repressor TGIF. HGF/SF is a multifunctional p