Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Suzanne Rademakers"'
Autor:
Joleen JH Traets, Servaas N van der Burght, Suzanne Rademakers, Gert Jansen, Jeroen S van Zon
Publikováno v:
eLife, Vol 10 (2021)
Cell fate is maintained over long timescales, yet molecular fluctuations can lead to spontaneous loss of this differentiated state. Our simulations identified a possible mechanism that explains life-long maintenance of ASE neuron fate in Caenorhabdit
Externí odkaz:
https://doaj.org/article/5d75689c480545208e8b7a52030a3fb3
Autor:
Tiffany A Timbers, Stephanie J Garland, Swetha Mohan, Stephane Flibotte, Mark Edgley, Quintin Muncaster, Vinci Au, Erica Li-Leger, Federico I Rosell, Jerry Cai, Suzanne Rademakers, Gert Jansen, Donald G Moerman, Michel R Leroux
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006235 (2016)
Forward genetic screens represent powerful, unbiased approaches to uncover novel components in any biological process. Such screens suffer from a major bottleneck, however, namely the cloning of corresponding genes causing the phenotypic variation. R
Externí odkaz:
https://doaj.org/article/92ee75ab091a429ab63000dd1b802093
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005733 (2015)
Cilia are sensory organelles present on almost all vertebrate cells. Cilium length is constant, but varies between cell types, indicating that cilium length is regulated. How this is achieved is unclear, but protein transport in cilia (intraflagellar
Externí odkaz:
https://doaj.org/article/37124a58beef44e487deecd0fdef3e2b
Autor:
Gert-Jan Kremers, Chunmei Li, Gert Jansen, Suzanne Rademakers, Jacque-Lynne Johnson, Michel R. Leroux, Servaas N. van der Burght, Adriaan B. Houtsmuller
Publikováno v:
Current Biology, 30(21), 4299-4306.e5. Cell Press
Primary cilia are ubiquitous antenna-like organelles that mediate cellular signaling and represent hotspots for human diseases termed ciliopathies. Within cilia, subcompartments are established to support signal transduction pathways, including Hedge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1069160ec64b41a7e9b91506cc7d2fe8
https://pubmed.ncbi.nlm.nih.gov/32916106
https://pubmed.ncbi.nlm.nih.gov/32916106
Autor:
Servaas N. van der Burght, Suzanne Rademakers, Jacque-Lynne Johnson, Chunmei Li, Gert-Jan Kremers, Adriaan B. Houtsmuller, Michel R. Leroux, Gert Jansen
Primary cilia are ubiquitous antenna-like organelles that mediate cellular signaling and represent hotspots for human diseases termed ciliopathies. How signaling subcompartments are established within the microtubule-based organelle, and for example
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df776593418f816359c15ca9a246f34
https://doi.org/10.1101/861955
https://doi.org/10.1101/861955
Publikováno v:
Journal of Cell Science, 126(8), 1785-1795. Company of Biologists Ltd
Summary Primary cilia are microtubule-based organelles that have important sensory functions. For their function, cilia rely on the delivery of specific proteins, both by intracellular trafficking and intraflagellar transport (IFT). In the cilia of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f8b804e6f8a706e8e9aba2bb468896
https://pure.eur.nl/en/publications/f509c435-7803-4c35-a5df-192230776921
https://pure.eur.nl/en/publications/f509c435-7803-4c35-a5df-192230776921
Autor:
Stephane Flibotte, Federico I. Rosell, Mark L. Edgley, Erica Li-Leger, Swetha Mohan, Suzanne Rademakers, Jerry Cai, Donald G. Moerman, Michel R. Leroux, Quintin Muncaster, Tiffany A. Timbers, Vinci Au, Gert Jansen, Stephanie J. Garland
Publikováno v:
PLoS Genetics (online), 12(8). Public Library of Science
PLoS Genetics, Vol 12, Iss 8, p e1006235 (2016)
PLoS Genetics
PLoS Genetics, Vol 12, Iss 8, p e1006235 (2016)
PLoS Genetics
Forward genetic screens represent powerful, unbiased approaches to uncover novel components in any biological process. Such screens suffer from a major bottleneck, however, namely the cloning of corresponding genes causing the phenotypic variation. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2723c0546ec4a08cc72b5c530d2b5db
https://doi.org/10.1371/journal.pgen.1006235
https://doi.org/10.1371/journal.pgen.1006235
Autor:
Ton de Jong, Suzanne Rademakers, Martijn P. J. Dekkers, Jan Burghoorn, Rob Willemsen, Gert Jansen
Publikováno v:
Proceedings of the National Academy of Sciences of the U.S.A., 104(17), 7157-7162. National Academy of Sciences
In the cilia of the nematode Caenorhabditis elegans , anterograde intraflagellar transport (IFT) is mediated by two kinesin-2 complexes, kinesin II and OSM-3 kinesin. These complexes function together in the cilia middle segments, whereas OSM-3 alone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a666b89bfa92b40e238ebfbb3abc1de
https://doi.org/10.1073/pnas.0606974104
https://doi.org/10.1073/pnas.0606974104
Publikováno v:
PLoS Genetics (online), 11(12). Public Library of Science
PLoS Genetics, Vol 11, Iss 12, p e1005733 (2015)
PLoS Genetics
PLoS Genetics, Vol 11, Iss 12, p e1005733 (2015)
PLoS Genetics
Cilia are sensory organelles present on almost all vertebrate cells. Cilium length is constant, but varies between cell types, indicating that cilium length is regulated. How this is achieved is unclear, but protein transport in cilia (intraflagellar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55e5c607ecd823196c43b711a13d766
https://pure.eur.nl/en/publications/77a194db-529c-4629-864c-5f82a2632e82
https://pure.eur.nl/en/publications/77a194db-529c-4629-864c-5f82a2632e82