Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Suzanne R. Kesten"'
Autor:
Stephen Joseph Johnson, Shelly A. Glase, Suzanne R. Kesten, Peter J. Manley, Lawrence D. Wise, Jon Wright, Thomas G. Heffner, Thomas A. Pugsley, Robert G. MacKenzie, Hyacinth C. Akunne
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1361-1366
A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamide dopamine (DA) D 3 receptor agonists has been identified. These compounds were found to be selective for DA D 3 over D 2 receptors and were shown to be partial to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b944dbffb56fd0b3f3b76b3ac650a3a3
https://doi.org/10.1016/0960-894x(96)00231-4
https://doi.org/10.1016/0960-894x(96)00231-4
Autor:
Walter H. Moos, Stephen Joseph Johnson, Sharie L. Myers, Michael R. Pavia, Suzanne R. Kesten, Roy D. Schwarz, Robert E. Davis, Sheila H. Hobbs, Linda L. Coughenour, David T. Dudley
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5c72bac365091fa5c5c42af714f78de
https://doi.org/10.1002/chin.199142186
https://doi.org/10.1002/chin.199142186
Autor:
Michael R. Pavia, Roy D. Schwarz, Robert E. Davis, Linda L. Coughenour, Stephen Joseph Johnson, Sharie L. Myers, David T. Dudley, Walter H. Moss, Sheila H. Hobbs, Suzanne R. Kesten
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 1:147-150
An oxazolidinone analogue of pilocarpine demonstrates muscarinic agonist-like properties in vitro at the acetylcholine-receptor. Replacement of the carbon alpha to the carbonyl in pilocarpine with a nitrogen represents the most active 2-oxazolidinone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1986ad776c0f5bc246f691c5030b5ee2
https://doi.org/10.1016/s0960-894x(01)80787-3
https://doi.org/10.1016/s0960-894x(01)80787-3
Autor:
Jon L. Wright, Tracy F. Gregory, Suzanne R. Kesten, Peter A. Boxer, Kevin A. Serpa, Leonard T. Meltzer, Lawrence D. Wise, Stephen A. Espitia, Christopher S. Konkoy, Edward R. Whittemore, Richard M. Woodward
Publikováno v:
Journal of medicinal chemistry. 43(18)
4-[4-(4-Benzylpiperidin-1-yl)but-1-ynyl]phenol (8) and 4-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]phenol (9) are potent NR1A/2B receptor antagonists (IC(50) values 0.17 and 0.10 microM, respectively). Administered intraperitoneally, they both potentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ce78d2d0d1f7b641bd2e7194787fe2
https://pubmed.ncbi.nlm.nih.gov/10978188
https://pubmed.ncbi.nlm.nih.gov/10978188
Autor:
Sui Xiong Cai, Christina T. Shipp, Zhang-Lin Zhou, Jon L. Wright, John F. W. Keana, Manuel Acosta-Burruel, Suzanne R. Kesten, Minhtam Tran, Edward R. Whittemore, Jon E. Hawkinson, Amir P. Tamiz, Anthony P. Guzikowski, Richard M. Woodward, Soo Hong-Bae
Publikováno v:
Journal of medicinal chemistry. 43(5)
Antagonists at the 1A/2B subtype of the NMDA receptor (NR1A/2B) are typically small molecules that consist of a 4-benzyl- or a 4-phenylpiperidine with an omega-phenylalkyl substituent on the heterocyclic nitrogen. Many of these antagonists, for examp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c80c74345698a25c0db862c1556d4e
https://pubmed.ncbi.nlm.nih.gov/10715162
https://pubmed.ncbi.nlm.nih.gov/10715162