Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Suzanne N. Shapira"'
Autor:
Sicheng Zhang, Kevin J. Williams, Amandine Verlande-Ferrero, Alvin P. Chan, Gino B. Su, Erin E. Kershaw, James E. Cox, John Alan Maschek, Suzanne N. Shapira, Heather R. Christofk, Thomas Q. de Aguiar Vallim, Selma Masri, Claudio J. Villanueva
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 2, Pp 100434- (2024)
Adipose tissue is the site of long-term energy storage. During the fasting state, exercise, and cold exposure, the white adipose tissue mobilizes energy for peripheral tissues through lipolysis. The mobilization of lipids from white adipose tissue to
Externí odkaz:
https://doaj.org/article/ff3c3ea9925a42a1b4513e62d017e176
Autor:
Anthony R. Angueira, Suzanne N. Shapira, Jeff Ishibashi, Samay Sampat, Jaimarie Sostre-Colón, Matthew J. Emmett, Paul M. Titchenell, Mitchell A. Lazar, Hee-Woong Lim, Patrick Seale
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 2869-2878.e4 (2020)
Summary: Brown adipose tissue (BAT) activity protects animals against hypothermia and represents a potential therapeutic target to combat obesity. The transcription factor early B cell factor-2 (EBF2) promotes brown adipocyte differentiation, but its
Externí odkaz:
https://doaj.org/article/d2804c928ea74363a16d4ff9dbecff3a
Autor:
Rachel R. Stine, Suzanne N. Shapira, Hee-Woong Lim, Jeff Ishibashi, Matthew Harms, Kyoung-Jae Won, Patrick Seale
Publikováno v:
Molecular Metabolism, Vol 5, Iss 1, Pp 57-65 (2016)
Objective: The induction of beige/brite adipose cells in white adipose tissue (WAT) is associated with protection against high fat diet-induced obesity and insulin resistance in animals. The helix-loop-helix transcription factor Early B-Cell Factor-2
Externí odkaz:
https://doaj.org/article/91206581c6554f5c854d543c61e46507
Publikováno v:
Cell Metabolism. 34:1906-1913
In this perspective, we provide an overview of a recently established National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) initiative, the Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-T2D). This program is designed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a529cda43be21ed77134b05b0e695eac
https://doi.org/10.1016/j.cmet.2022.09.013
https://doi.org/10.1016/j.cmet.2022.09.013
Autor:
Paul M. Titchenell, Patrick Seale, Jeff Ishibashi, Suzanne N. Shapira, Mitchell A. Lazar, Anthony R. Angueira, Hee-Woong Lim, Matthew J. Emmett, Samay Sampat, Jaimarie Sostre-Colón
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 2869-2878.e4 (2020)
Cell reports
Cell reports
SUMMARY Brown adipose tissue (BAT) activity protects animals against hypothermia and represents a potential therapeutic target to combat obesity. The transcription factor early B cell factor-2 (EBF2) promotes brown adipocyte differentiation, but its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0caa3320a252bbdbc20186ebd9563631
http://www.sciencedirect.com/science/article/pii/S2211124720301777
http://www.sciencedirect.com/science/article/pii/S2211124720301777
Autor:
Patrick Seale, Suzanne N. Shapira
Publikováno v:
Obesity (Silver Spring, Md.)
Adipose tissue, once viewed as an inert organ of energy storage, is now appreciated to be a central node for the dynamic regulation of systemic metabolism. There are three general types of adipose tissue: white, brown, and brown-in-white or "beige" f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3aa00d930bc5284c72ee10d5e51a316
https://doi.org/10.1002/oby.22334
https://doi.org/10.1002/oby.22334
Publikováno v:
Trends Cell Biol
Trends in cell biology, vol 30, iss 7
Trends in cell biology, vol 30, iss 7
Adult tissue stem cells mediate organ homeostasis and regeneration and thus are continually making decisions about whether to remain quiescent, proliferate, or differentiate into mature cell types. These decisions often integrate external cues, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9371caba48f6e4d12b50f6155b1fa79
https://europepmc.org/articles/PMC8059102/
https://europepmc.org/articles/PMC8059102/
Autor:
Hee-Woong Lim, Jeff Ishibashi, Kyoung-Jae Won, Rachel R. Stine, Matthew J. Harms, Suzanne N. Shapira, Patrick Seale
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 1, Pp 57-65 (2016)
Molecular Metabolism, Vol 5, Iss 1, Pp 57-65 (2016)
Objective The induction of beige/brite adipose cells in white adipose tissue (WAT) is associated with protection against high fat diet-induced obesity and insulin resistance in animals. The helix-loop-helix transcription factor Early B-Cell Factor-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043e59bd8318c09cf04febf8aa847c8c
Autor:
Suzanne N. Shapira, Patrick Seale
Publikováno v:
Nature cell biology. 19(9)
Brown adipose tissue is a key metabolic organ that oxidizes fatty acids and glucose to generate heat. Through epigenomic analyses of multiple adipose depots, the transcription factor nuclear factor I-A (NFIA) is now shown to drive the brown fat genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9df89aa2dd98ab3dff9a0d0070081a
https://pubmed.ncbi.nlm.nih.gov/28855730
https://pubmed.ncbi.nlm.nih.gov/28855730
Autor:
Jeff Ishibashi, Hee-Woong Lim, Suzanne N. Shapira, Patrick Seale, Kyoung-Jae Won, Alexander P. Sakers, Sona Rajakumari, Matthew J. Harms
The transcription factor early B-cell factor 2 (EBF2) is an essential mediator of brown adipocyte commitment and terminal differentiation. However, the mechanisms by which EBF2 regulates chromatin to activate brown fat-specific genes in adipocytes we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d626c08140ad0ad215181e4a7a575c82
https://europepmc.org/articles/PMC5411707/
https://europepmc.org/articles/PMC5411707/