Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Suzanne McGehee"'
Autor:
Richard N. Bergman, Mary Walter, Peter Herscovitch, Yaron Rotman, Joyce D. Linderman, Fink Ya, Alison S. Baskin, Marilyn Ader, James W. Johnson, Chen Ky, Zahraa Abdul Sater, Robert J. Brychta, Francesca Piccinini, Suzanne McGehee, Laura A. Fletcher, Norman B. Javitt, William Dieckmann, Cai H, Corina Millo, Devika Kapuria, ero C, Peter Walter, Thomas M. Cassimatis, Alana E O'Mara, Brooks P. Leitner, Kelsey N, Aaron M. Cypess
Publikováno v:
J Clin Invest
BACKGROUND: Mirabegron is a β3-adrenergic receptor (β3-AR) agonist approved only for the treatment of overactive bladder. Encouraging preclinical results suggest that β3-AR agonists could also improve obesity-related metabolic disease by increasin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205ae0ed58abe4365ef446ae9710878c
https://doi.org/10.1172/jci131126
https://doi.org/10.1172/jci131126
Autor:
Kong Y. Chen, Marc L. Reitman, Robert J. Brychta, Shanna Bernstein, Brooks P. Leitner, Sarah L Bell, Laura A. Fletcher, Aaron M. Cypess, Amber B. Courville, Jacob D. Hattenbach, Courtney J. Duckworth, Suzanne McGehee, Ranganath Muniyappa, Thomas M. Cassimatis, Nikita Sanjay Israni
Publikováno v:
Journal of the Endocrine Society
Design and rationale: Obesity results from energy intake exceeding energy expenditure (EE) over a prolonged period. Many anti-obesity drugs are designed to decrease energy intake. However, their potential impact on EE is not well documented. We desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc15eaa6a5f08481e1b8a6c875196ca
http://europepmc.org/articles/PMC7209218
http://europepmc.org/articles/PMC7209218
Autor:
Alexis Ayuketah, Megan Zhou, Hongyi Cai, Michael Stagliano, Ciarán G. Forde, Juen Guo, Laura A. Fletcher, Elise Costa, Irene Rozga, Rebecca Howard, Valerie L. Darcey, Ahmed M. Gharib, Mary Walter, Robert J. Brychta, Ronald Ouwerkerk, Kong Y. Chen, Paule V. Joseph, Stephanie T. Chung, Thomas M. Cassimatis, Amber B. Courville, Klaudia Raisinger, Kevin D. Hall, Shanna Yang, Peter Walter, Suzanne McGehee
Publikováno v:
Cell Metab
Cell Metabolism 30 (2019) 1
Cell Metabolism, 30(1), 67-77.e3
Cell Metabolism 30 (2019) 1
Cell Metabolism, 30(1), 67-77.e3
We investigated whether ultra-processed foods affect energy intake in 20 weight-stable adults, aged (mean±SE) 31.2±1.6 y and BMI=27±1.5 kg/m(2). Subjects were admitted to the NIH Clinical Center and randomized to receive either ultra-processed or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251423606d44c5b0078088db6b3a7d38
https://europepmc.org/articles/PMC7959109/
https://europepmc.org/articles/PMC7959109/
Autor:
Molly S. Halprin, Robert J. Brychta, Aaron M. Cypess, Alana E O'Mara, Kong Y. Chen, Laura A. Fletcher, Brooks P. Leitner, Thomas M. Cassimatis, Suzanne McGehee, James W. Johnson, Katherine Kim
Publikováno v:
Obesity (Silver Spring)
Objective This study aimed to quantify and compare the amount, activity, and anatomical distribution of cold-activated brown adipose tissue (BAT) in healthy, young, lean women and men. Methods BAT volume and 18 F-fluorodeoxyglucose uptake were measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c20bb59890c5e0232aaab0ff7c48df3
https://pubmed.ncbi.nlm.nih.gov/31970907
https://pubmed.ncbi.nlm.nih.gov/31970907
Autor:
Suzanne McGehee, Alana E O'Mara, Brooks P. Leitner, Cheryl Cero, Yaron Rotman, Aaron M. Cypess, Laura A. Fletcher, Joyce D. Linderman, Robert J. Brychta, Devika Kapuria, James W. Johnson
Publikováno v:
Diabetes. 67
Background: Brown Adipose Tissue (BAT) in adult humans has become increasingly recognized to contribute to energy consumption and modulate metabolism. To date, BAT stimulation has predominately relied on cold exposure. However, long-term cold exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0fbaa785fc6bde349e071f6db8e323
https://doi.org/10.2337/db18-1146-p
https://doi.org/10.2337/db18-1146-p
Autor:
Robert J. Brychta, Suzanne McGehee, Kong Y. Chen, Laura A. Fletcher, Katherine Kim, Aaron M. Cypess, Brooks P. Leitner
Publikováno v:
Diabetes. 67
Background: Cold stimulation of human brown adipose tissue (BAT) can increase its glucose uptake and energy expenditure, making it a potential target for treating obesity and metabolic disease. BAT is commonly found in deeper fascial layers of specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47a38d5b542219e21c4ecb78f75576f7
https://doi.org/10.2337/db18-2052-p
https://doi.org/10.2337/db18-2052-p
Autor:
Courtney J. Duckworth, James W. Johnson, Suzanne McGehee, Peter Herscovitch, H. Martin Garraffo, Michael A. Kiebish, Alison S. Baskin, Laura A. Fletcher, Brooks P. Leitner, Niven R. Narain, Cheryl Cero, Corina Millo, Fei Gao, Joyce D. Linderman, Peter Walter, William Dieckmann, Robert J. Brychta, Kong Y. Chen, Esti Anflick-Chames, Vladimir Tolstikov, Hongyi Cai, Alana E O'Mara, Emily Y. Chen, Aaron M. Cypess, Shan Huang
Publikováno v:
Diabetes. 67(10)
β3-adrenergic receptor (AR) agonists are approved to treat only overactive bladder. However, rodent studies suggest that these drugs could have other beneficial effects on human metabolism. We performed tissue receptor profiling and showed that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205a769d359d2f52568b395290df94c4
https://pubmed.ncbi.nlm.nih.gov/29980535
https://pubmed.ncbi.nlm.nih.gov/29980535
Autor:
Ilan Tal, Brooks P. Leitner, Garima Gupta, Robert J. Brychta, Shan Huang, Courtney J. Duckworth, Aaron M. Cypess, Kong Y. Chen, William Dieckmann, Suzanne McGehee, Gerald M. Kolodny, Peter Herscovitch, Alison S. Baskin, Karel Pacak
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(32)
Human brown adipose tissue (BAT) can be activated to increase glucose uptake and energy expenditure, making it a potential target for treating obesity and metabolic disease. Data on the functional and anatomic characteristics of BAT are limited, howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a159ba980ede7987775f4a1da7709c
https://pubmed.ncbi.nlm.nih.gov/28799553
https://pubmed.ncbi.nlm.nih.gov/28799553
Autor:
Brooks P. Leitner, Courtney J. Duckworth, Robert J. Brychta, Sarah A. Smyth, Suzanne McGehee, Jacob D. Hattenbach, Kong Y. Chen, Shan Huang
Publikováno v:
Medicine & Science in Sports & Exercise. 48:541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fca1e2aaf81382f3ec4eb42faccc066
https://doi.org/10.1249/01.mss.0000486628.22171.c8
https://doi.org/10.1249/01.mss.0000486628.22171.c8