Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Suzanne M. Quartuccio"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 3 (2015)
The mammalian genome encodes three Aurora kinase protein family members: A, B, and C. While Aurora kinase A (AURKA) and B (AURKB) are found in cells throughout the body, significant protein levels of Aurora kinase C (AURKC) are limited to cells that
Externí odkaz:
https://doaj.org/article/5de2c9eb037e4bfb9b399aa3696165c7
Autor:
Eoghainín Ó hAinmhire, Suzanne M Quartuccio, Whay Cheng, Roshan A Ahmed, Shelby M King, Joanna E Burdette
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89553 (2014)
Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of high-grade serous ovarian carcinomas, demonstrating its critical role. Additionally, the Transformin
Externí odkaz:
https://doaj.org/article/f96d07137ceb4af39b4e4d5c53e1082f
Publikováno v:
microPublication Biology
The Aurora protein kinases (AURK) are essential regulators of chromosome segregation in mitotic and meiotic cell divisions (Carmena and Earnshaw 2003). Unlike mitotically dividing cells which express two AURKs (AURKA and AURKB), mammalian oocytes, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26110bea81063b86068dadc76f0ce77e
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65067 (2013)
Epithelial ovarian cancer is the most lethal gynecological malignancy among US women. The etiology of this disease, although poorly understood, may involve the ovarian surface epithelium or the epithelium of the fallopian tube fimbriae as the progeni
Externí odkaz:
https://doaj.org/article/6ac7fc08f8194c73b45f3299f29d7751
Publikováno v:
Molecular Biology of the Cell
Use of mouse oocytes that only express Aurora kinase B as the catalytic subunit of the chromosomal passenger complex (CPC) provides evidence indicating differential capacities of AURKB– and AURKC–CPC complexes at a distinct localization.
Ane
Ane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b360b9b00a4e6578301265ab5b6d7f
https://doi.org/10.1091/mbc.e16-12-0850
https://doi.org/10.1091/mbc.e16-12-0850
Autor:
Rajul Kothari, Suzanne M. Quartuccio, Sharon L. Eddie, Jessica A. Shepherd, Joanna E. Burdette, Jie Zhu, J. Julie Kim, Teresa K. Woodruff
Publikováno v:
Gynecologic Oncology. 136:348-354
Objective Ovarian cancer is the most lethal gynecological malignancy that affects women. Recent data suggests that the disease may originate in the fallopian fimbriae; however, the anatomical origin of ovarian carcinogenesis remains unclear. This is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bea4e603af9e475cdaf65dadfd26b7e
https://doi.org/10.1016/j.ygyno.2014.12.015
https://doi.org/10.1016/j.ygyno.2014.12.015
Autor:
Alexandra L. Nguyen, Karen Schindler, David Drutovic, Ahmed Z. Balboula, Petr Solc, Amanda S. Gentilello, Suzanne M. Quartuccio
Publikováno v:
Journal of Cell Science.
Meiotic oocytes lack classic centrosomes and therefore, bipolar spindle assembly depends on clustering of acentriolar microtubule-organizing centers (MTOCs) into two poles. However, the molecular mechanism regulating MTOCs assembly into two poles is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3ca29273ecf473647df5e7d4fe1179
https://doi.org/10.1242/jcs.189340
https://doi.org/10.1242/jcs.189340
Autor:
Suzanne M, Quartuccio, Subbulakshmi, Karthikeyan, Sharon L, Eddie, Daniel D, Lantvit, Eoghainín, Ó hAinmhire, Dimple A, Modi, Jian-Jun, Wei, Joanna E, Burdette
Publikováno v:
International journal of cancer. 137(7)
Ovarian cancer is the fifth leading cause of cancer death among US women. Evidence supports the hypothesis that high-grade serous ovarian cancers (HGSC) may originate in the distal end of the fallopian tube. Although a heterogeneous disease, 96% of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8ed1f4a97b16a6a14fb8a7af38c0b9c
https://pubmed.ncbi.nlm.nih.gov/25810107
https://pubmed.ncbi.nlm.nih.gov/25810107
Autor:
Roshan A. Ahmed, Suzanne M. Quartuccio, Joanna E. Burdette, Whay Cheng, Shelby M. King, Eoghainín Ó hAinmhire
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89553 (2014)
PLoS ONE
PLoS ONE
Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of high-grade serous ovarian carcinomas, demonstrating its critical role. Additionally, the Transformin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895dd216a65bef350f57da4d5edd93ac
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586866/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586866/pdf/?tool=EBI
Our results confirm that single alterations in pathways associated with high-grade serous cancer are not sufficient to drive soft agar colony formation as an index of transformation, but that specific combinations such as KRAS/PTEN and mutant p53/PTE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27635f863f01ce7405c169bbda192e5c
https://doi.org/10.21236/ada598580
https://doi.org/10.21236/ada598580
