Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Suzanne M. Pritchard"'
Herpes Simplex Virus 1 Glycoprotein B from a Hyperfusogenic Virus Mediates Enhanced Cell–Cell Fusion
Autor:
Katrina A. Gianopulos, Albina O. Makio, Suzanne M. Pritchard, Cristina W. Cunha, McKenna A. Hull, Anthony V. Nicola
Publikováno v:
Viruses, Vol 16, Iss 2, p 251 (2024)
Herpes simplex virus 1 (HSV-1) causes significant morbidity and death in humans worldwide. Herpes simplex virus 1 has a complex fusion mechanism that is incompletely understood. The HSV-1 strain ANG has notable fusion and entry activities that distin
Externí odkaz:
https://doaj.org/article/646d4e5541b44af888d96699df7ef2a0
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Herpes simplex virus 1 (HSV-1) commandeers the host cell proteasome at several steps of its replication cycle, including entry. Here we demonstrate that HSV-2, pseudorabies virus (PRV), and bovine herpesvirus 1 (BoHV-1) entry are blocked by
Externí odkaz:
https://doaj.org/article/525d5b0deef74e61ac1ba8dd2c882318
Autor:
Tri Komala Sari, Katrina A. Gianopulos, Darin J. Weed, Seth M. Schneider, Suzanne M. Pritchard, Anthony V. Nicola
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT Herpes simplex viruses (HSVs) cause significant morbidity and mortality in humans worldwide. Herpesviruses mediate entry by a multicomponent virus-encoded machinery. Herpesviruses enter cells by endosomal low-pH and pH-neutral mechanisms in
Externí odkaz:
https://doaj.org/article/106fc3ec4ff3483b94f755349a82042b
Autor:
Seth M. Schneider, Suzanne M. Pritchard, George A. Wudiri, Chasity E. Trammell, Anthony V. Nicola
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Viruses commandeer host cell 26S proteasome activity to promote viral entry, gene expression, replication, assembly, and egress. Proteasomal degradation activity is critical for herpes simplex virus (HSV) infection. The proteasome inhibitor
Externí odkaz:
https://doaj.org/article/009adb537de94edba977771e626954c3
Autor:
Katrina A. Gianopulos, Tri Komala Sari, Darin J. Weed, Suzanne M. Pritchard, Anthony V. Nicola
Publikováno v:
J Virol
Low endosomal pH facilitates herpesvirus entry in a cell-specific manner. Herpes simplex virus 1 (HSV-1) causes significant morbidity and death in humans worldwide. HSV-1 enters cells by low-pH and neutral-pH pathways. Low-pH-induced conformational c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6808ff3a49d29bfcc4e24b63b22d684
https://doi.org/10.1128/jvi.00163-22
https://doi.org/10.1128/jvi.00163-22
Autor:
Cristina W Cunha, Kathryne E Taylor, Suzanne M Pritchard, Mark G Delboy, Tri Komala Sari, Hector C Aguilar, Karen L Mossman, Anthony V Nicola
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131129 (2015)
Herpes simplex virus 1 (HSV-1) ICP0 is a multi-functional phosphoprotein expressed with immediate early kinetics. An ICP0 deletion mutant, HSV-1 dl1403, has been widely used to study the roles of ICP0 in the HSV-1 replication cycle including gene exp
Externí odkaz:
https://doaj.org/article/1934340ecbc34161a73185b40e63238d
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70889 (2013)
ICP4 is the major transcriptional regulatory protein of herpes simplex virus (HSV). It is expressed in infected cells with immediate early kinetics and is essential for viral growth. ICP4 is also a structural component of the virion tegument layer. H
Externí odkaz:
https://doaj.org/article/57093067869d4715be79ea7bee5bcc87
Publikováno v:
J Virol
Herpes simplex virus 1 (HSV-1) causes significant morbidity and mortality in humans worldwide. HSV-1 enters epithelial cells via an endocytosis mechanism that is low-pH dependent. However, the precise intracellular pathway has not been identified, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb7f0dae0749066d5e009c67feb306f
https://europepmc.org/articles/PMC7925185/
https://europepmc.org/articles/PMC7925185/
Autor:
Seth M. Schneider, Darin J. Weed, Suzanne M. Pritchard, Anthony V. Nicola, Tri Komala Sari, Katrina A. Gianopulos
Publikováno v:
mSphere, Vol 5, Iss 1, p e00826-19 (2020)
mSphere
mSphere, Vol 5, Iss 1 (2020)
mSphere
mSphere, Vol 5, Iss 1 (2020)
Herpesviruses are ubiquitous pathogens that cause lifelong latent infections and that are characterized by multiple entry pathways. We propose that herpes simplex virus (HSV) gC plays a selective role in modulating HSV entry, such as entry into epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b150f0c4003c141383691e266b121685
https://doaj.org/article/7817e654fa684d1d9112c03a705b0e02
https://doaj.org/article/7817e654fa684d1d9112c03a705b0e02
Autor:
Tri Komala Sari, Seth M. Schneider, Darin J. Weed, Suzanne M. Pritchard, Anthony V. Nicola, Katrina A. Gianopulos
Herpes simplex viruses (HSVs) cause significant morbidity and mortality in humans worldwide. Herpesviruses mediate entry by a multi-component, virus-encoded machinery. Herpesviruses enter cells by endosomal low pH and pH-neutral mechanisms in a cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71f3f5d44edeaf29375de43b38f3445