Acute lymphoblastic leukaemia cells produce large extracellular vesicles containing organelles and an active cytoskeleton

Autor: Suzanne M. Johnson, Clare Dempsey, Catriona Parker, Aleksandr Mironov, Helen Bradley, Vaskar Saha

Publikováno v: Journal of Extracellular Vesicles, Vol 6, Iss 1 (2017)

Extracellular vesicles have been described in non-paracrine cellular interactions in cancer. We report a similar phenomenon in B-cell precursor (BCP) acute lymphoblastic leukaemia (ALL). Using advanced microscopy and high throughput screening, we fur

Externí odkaz: https://doaj.org/article/7e5f9f2d81e44b7e90335dd8e193d144

Large extracellular vesicles can be characterised by multiplex labelling using imaging flow cytometry

Autor: Suzanne M. Johnson, Martin G. McCabe, Christopher Smith, Alexander A. Mironov, Antonia Banyard

Publikováno v: Johnson, S M, Banyard, A, Smith, C, Mironov, A & Mccabe, M G 2020, ' Large Extracellular Vesicles Can be Characterised by Multiplex Labelling Using Imaging Flow Cytometry ', International Journal of Molecular Sciences, vol. 21, no. 22, 8723, pp. 1-23 . https://doi.org/10.3390/ijms21228723, https://doi.org/10.3390/ijms21228723
International Journal of Molecular Sciences, Vol 21, Iss 8723, p 8723 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 22

Extracellular vesicles (EVs) are heterogeneous in size (30 nm&ndash
10 µ
m), content (lipid, RNA, DNA, protein), and potential function(s). Many isolation techniques routinely discard the large EVs at the early stages of small EV or ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ba7d8845031a5b2ced36ec4e96f588

Cytokine Profiles from Antigen-Stimulated Whole-Blood Samples among Patients with Pulmonary or Nonmeningeal Disseminated Coccidioidomycosis

Autor: Demosthenes Pappagianis, Kenneth S. Knox, Neil M. Ampel, Chinh Nguyen, Suzanne M. Johnson, Lance A. Nesbit, Suzette Chavez

Publikováno v: Clinical and Vaccine Immunology. 22:917-922

The outcome of coccidioidomycosis depends on a robust specific cellular immune response. A T-helper type 1 (Th1) cellular immune response has been previously associated with resolution of clinical illness. However, the precise elements of this respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a77d033297e16e9bad6831a5a6d56be
https://doi.org/10.1128/cvi.00280-15

Determination of Ribosomal DNA Copy Number and Comparison Among Strains of Coccidioides

Autor: Demosthenes Pappagianis, Erin L. Carlson, Suzanne M. Johnson

Publikováno v: Mycopathologia. 179:45-51

The use of PCR-based assays to detect fungi and diagnose fungal infections as well as to monitor fungal organ burden with diseases such as coccidioidomycosis is becoming more common. The target of these assays is frequently one or more of the ribosom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddaf0a483e6585796e604430e4c46d3
https://doi.org/10.1007/s11046-014-9820-y

Detection of coccidioidal antibodies in serum of a small rodent community in Baja California, Mexico

Autor: Raúl C. Baptista-Rosas, Ricardo Eaton, Jovani Catalan-Dibene, Suzanne M. Johnson, Meritxell Riquelme, Adriana L. Romero-Olivares, Demosthenes Pappagianis

Publikováno v: Fungal Biology. 118:330-339

Coccidioidomycosis (Valley Fever) represents a serious threat to inhabitants of endemic areas of North America. Despite successful clinical isolations of the fungal etiological agent, Coccidioides spp., the screening of environmental samples has had

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914a69db9c8edbb532391786ca2a6e0b
https://doi.org/10.1016/j.funbio.2014.01.006