Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Suzanne M. Gignac"'
Publikováno v:
Leukemialymphoma. 4(5-6)
Cytochemical staining of "non-specific esterases" is commonly used in the classification of acute leukemias. In the biochemical nomenclature these enzymes represent the "carboxylesterases (EC 3.1.1.1)" and are mostly visualized by a substrate-diazoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8f21f8da4b75fc5b600b8f05a4080a
https://pubmed.ncbi.nlm.nih.gov/27467661
https://pubmed.ncbi.nlm.nih.gov/27467661
Publikováno v:
Leukemialymphoma. 5(5-6)
We analyzed the acid phosphatase (AcP) isoenzyme profiles of normal and malignant hematopoietic cells using isoelectric focusing followed by diazo staining. Reproducibly defined bands and band complexes could be identified and were correlated with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff620fe59339b091bfae2f00acbeec6
https://pubmed.ncbi.nlm.nih.gov/27463338
https://pubmed.ncbi.nlm.nih.gov/27463338
Autor:
Suzanne M. Gignac, A. Victor Hoffbrand, R. Michael Roberts, Michael Buschle, Hans G. Drexler, George R. Pettit
Publikováno v:
Leukemialymphoma. 3(1)
Purified B-cells from normal tonsils and from the peripheral blood of eight patients with B-chronic lymphocytic leukemia (B-CLL) were treated in vitro with the protein kinase C (PKC) activators TPA, Bryostatin 1 (Bryo), mezerein, with the calcium ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0a79ab3cb4888c6873aa47cd4870d9
https://pubmed.ncbi.nlm.nih.gov/27457194
https://pubmed.ncbi.nlm.nih.gov/27457194
Autor:
Suzanne M. Gignac, Hartmut Kabisch, Roderick A.F. MacLeod, Hans G. Drexler, Hilmar Quentmeier, Gerhard Gaedicke, Zhenbo Hu, Dörthe Teepe, Klaus G. Steube, T. E. Hansen-Hagge, D. Harms
Publikováno v:
Leukemia & Lymphoma. 25:345-363
Myelodysplastic syndrome (MDS) in childhood is considered to be very rare and detailed pathobiological data are scarce. More biological information regarding MDS in children is clearly needed and in vitro culture studies provide one possibility for g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b40559906183754a72071edb31f844
https://doi.org/10.3109/10428199709114174
https://doi.org/10.3109/10428199709114174
Autor:
Cord C. Uphoff, Suzanne M. Gignac, Zhen-Bo Hu, Maren Voges, Elke Fleckenstein, Anne Hopert, Hans G. Drexler
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 30:344-347
Mycoplasmal contamination remains a significant impediment to the culture of eukaryotic cells. For certain cultures, attempts to eliminate the infection are feasible alternatives to the normally recommended disposal of the contaminated culture. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e62d0b81561c88290aedf3e546159051
https://doi.org/10.1007/bf02631456
https://doi.org/10.1007/bf02631456
Publikováno v:
Blood. 82:1599-1607
Myeloperoxidase (MPO) is found exclusively in the azurophilic granules (primary lysosomes) of normal myelomonocytic cells. Cytochemical staining for MPO activity is used clinically to distinguish myeloid from lymphoid leukemias. We studied the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bf516955be46f05808145e66e9bdffb
https://doi.org/10.1182/blood.v82.5.1599.1599
https://doi.org/10.1182/blood.v82.5.1599.1599
Autor:
Suzanne M. Gignac, Zhen-Bo Hu, Hans G. Drexler, Klaus G. Steube, Hilmar Quentmeier, Cord C. Uphoff
Publikováno v:
Leukemia & Lymphoma. 10:135-142
The effects of bryostatin 1 (Bryo 1), a protein kinase C (PKC) activator, on proliferation, differentiation and macromolecular synthesis were investigated in the two cell lines EHEB and JVM-2, established from patients with chronic B-cell leukemia. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d7d8e486150b2f76bf4f6553ef2e2f
https://doi.org/10.3109/10428199309147367
https://doi.org/10.3109/10428199309147367
Autor:
Klaus G. Steube, J. W. G. Janssen, Hilmar Quentmeier, Roderick A.F. MacLeod, Lothar Schleithoff, Suzanne M. Gignac, Hans G. Drexler
Publikováno v:
Leukemia & Lymphoma. 10:359-368
A common problem in cell culturing is cross-contamination with other cells or misidentification of cells. An effective cell culture quality and identity control is required in order to avoid inter- and intraspecies contamination of cell lines and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bb7baa7ea815039c20d8b05b90ddba
https://doi.org/10.3109/10428199309148561
https://doi.org/10.3109/10428199309148561
Autor:
Hans G. Drexler, Klaus G. Steube, Cord C. Uphoff, Suzanne M. Gignac, Roderick A.F. MacLeod, Maren Voges
Publikováno v:
Leukemia Research. 16:815-822
Thirty-nine continuous adherent or suspension cell lines were treated with a quinolone antibiotic, Mycoplasma Removal Agent (MRA), for the elimination of chronic mycoplasma contamination. In preliminary experiments MRA did not show any cytostatic or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274523984e65dd53e7365271d0ec8e2c
https://doi.org/10.1016/0145-2126(92)90161-y
https://doi.org/10.1016/0145-2126(92)90161-y
Publikováno v:
Journal of Immunological Methods. 149:43-53
19 suspension cell lines were treated with antibiotics for elimination of chronic contamination with mycoplasma. We compared the efficiency, cytotoxicity and cross-resistance of the commercially available antibiotics MRA (Mycoplasma Removal Agent, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9149cad7072ee8a97399f3208ddd9fc6
https://doi.org/10.1016/s0022-1759(12)80047-0
https://doi.org/10.1016/s0022-1759(12)80047-0