Výsledky vyhledávání - "Suzanne M. Benjes"

The BCR gene recombines preferentially with Alu elements in complex BCR- ABL translocations of chronic myeloid leukaemia

Autor: Suzanne M. Benjes, Christine M. Morris, Stephen J. Sowerby, Tania L. Smith, Aaron Jeffs

Publikováno v: Human Molecular Genetics. 7:767-776

Chronic myeloid leukaemia (CML) develops when two genes, BCR on chromosome 22 and ABL on chromosome 9, recombine to form a hybrid BCR-ABL gene with leukaemogenic properties. The mechanism which underlies this recombination is unknown, but additional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2cb8c744ed9ca1f1910651ab080228
https://doi.org/10.1093/hmg/7.5.767

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Deletion 20q in association with Philadelphia chromosome positive acute lymphoblastic leukemia

Autor: Peter E. Hollings, Ingrid Rosman, Peter H. Fitzgerald, Suzanne M. Benjes

Publikováno v: Cancer Genetics and Cytogenetics. 79:32-35

Cytogenetic deletions involving the long arm of chromosome 20 are thought to be characteristic of myeloid disorders. We report clinical and cytogenetic observations of two adult patients with Philadelphia chromosome positive acute lymphoblastic leuke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb68124c8db7dd4caf22f335aad4ba21
https://doi.org/10.1016/0165-4608(94)00068-m

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BCR-ABL1

Autor: Christine M. Morris, Suzanne M. Benjes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6fac3140ec7942ff7e12a25ad730b50
https://doi.org/10.1007/978-3-642-16483-5_571

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LINE-1 Elements

Autor: Suzanne M. Benjes, Christine M. Morris

Publikováno v: Encyclopedia of Cancer ISBN: 9783642278419

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28777a72eec6137c34fc0c9f45411d4
https://doi.org/10.1007/978-3-642-16483-5_3360

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BCR-ABL1

Autor: Christine M. Morris, Suzanne M. Benjes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2644b07e71c963a663bbddbdd1fb3db6
https://doi.org/10.1007/978-3-540-47648-1_571

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A full-length and potentially active LINE element is integrated polymorphically within the IGL locus in a genomically unstable region of chromosome 22

Autor: Suzanne M. Benjes, Christine M. Morris

Publikováno v: Human genetics. 109(6)

Leukemic cells of a patient diagnosed with chronic myeloid leukemia (CML) showed a complex BCR-ABL1 rearrangement hidden within a normal appearing karyotype. Previous molecular studies had established that the 3' BCR had recombined at a novel site wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd7e711fe64d772a79a158fe5b0a05d
https://pubmed.ncbi.nlm.nih.gov/11810275

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Oligoclonal B-cell leukemia characterized by spontaneous cell division and telomere association

Autor: Peter E. Hollings, Suzanne M. Benjes, Peter E. Crossen, J. C. Nimmo, M. E. J. Beard, Mary J. Morrison, Sandra M. Tully

Publikováno v: Genes, chromosomescancer. 8(1)

Cytogenetic analysis of unstimulated cultures from a female patient with chronic B-cell leukemia (CLL) revealed three cytogenetically distinct clones, suggesting that the patient's leukemia was oligoclonal. Immunoglobulin heavy chain gene rearrangeme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747f43589c60d0151ec590b49b4bba4f
https://pubmed.ncbi.nlm.nih.gov/7691159

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