Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Suzanne M Escolme"'
Autor:
Daniel Swan, John C. Mathers, Joy E J Hardyman, Helen Bosomworth, Ruth A. Valentine, Suzanne M Escolme, Dianne Ford, Luisa A. Wakeling, Laura J. Ions
Publikováno v:
AGE. 35:1835-1849
Changes in DNA methylation across the life course may contribute to the ageing process. We hypothesised that some effects of dietary restriction to extend lifespan and/or mitigate against features of ageing result from changes in DNA methylation, so
Autor:
Dianne Ford, Simon Cockell, Jill A. McKay, Laura J. Ions, Suzanne M Escolme, Luisa A. Wakeling, Madhurima Dey, Gail Jenkins, Emily V Hampton, Linda Jane Wainwright, Tianhong Su
Publikováno v:
Human Genomics
Background SIRT1 is likely to play a role in the extension in healthspan induced by dietary restriction. Actions of SIRT1 are pleiotropic, and effects on healthspan may include effects on DNA methylation. Polycomb group protein target genes (PCGTs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c07e29874e6002762d76fc867722d4
https://nrl.northumbria.ac.uk/id/eprint/26779/1/SIRT1.pdf
https://nrl.northumbria.ac.uk/id/eprint/26779/1/SIRT1.pdf
Publikováno v:
Proceedings of the Nutrition Society. 72