Implications of Introducing High-Sensitivity Cardiac Troponin T Into Clinical Practice

Autor: Dina Melki, Kai M. Eggers, Joakim Alfredsson, Suzanne Lind, Johan Lugnegård, Tomas Jernberg, Bertil Lindahl

Publikováno v: Journal of the American College of Cardiology. 65:1655-1664

Background Cardiac troponin is the preferred biomarker for diagnosing myocardial infarction (MI). Objectives The aim of this study was to examine the implications of introducing high-sensitivity cardiac troponin T (hs-cTnT) into clinical practice and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b24d52a7e02ad7d8a6f8cc81fdfbca
https://doi.org/10.1016/j.jacc.2015.02.044

Growth Hormone Induces Low-Density Lipoprotein Clearance but not Bile Acid Synthesis in Humans

Autor: Lars Berglund, Birgit Borgström, Gösta Eggertsen, S. Ericsson, Hans Olivecrona, Suzanne Lind, Mats Rudling, Bo Angelin, Mats Eriksson

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 24:349-356

Objective— Growth hormone (GH) induces hepatic low-density lipoprotein (LDL) receptors and lowers plasma cholesterol. We characterized the influence of GH treatment on plasma LDL clearance in normal humans and investigated the relative role of LDL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93617eb0d917cc5d03e3e359ad5ec6c8
https://doi.org/10.1161/01.atv.0000110657.67317.90

Prognostic value of combining high sensitive troponin T and N-terminal pro B-type natriuretic peptide in chest pain patients with no persistent ST-elevation

Autor: Tomas Jernberg, Stefan Agewall, Dina Melki, Suzanne Lind

Publikováno v: Clinica chimica acta; international journal of clinical chemistry. 413(9-10)

The aim was to examine whether high sensitive troponin T (Hs-TnT) is better than conventional troponins to risk stratify chest pain patients, in particular when applying early serial measurements or combining with natriuretic peptides. Samples were o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1d68eca0dbed7d49295c6d61abb0b2
https://pubmed.ncbi.nlm.nih.gov/22366164

CLINICAL EFFECTS OF INTRODUCING HIGH SENSITIVE CARDIAC TROPONIN T INTO CLINICAL PRACTICE: DATA FROM 48,594 PATIENTS IN THE SWEDEHEART REGISTRY

Autor: Per Johanson, Tomas Jernberg, Suzanne Lind, Kai M. Eggers, Bertil Lindahl, Johan Lugnegård, Dina Melki, Joakim Alfredsson

Publikováno v: Journal of the American College of Cardiology. 63:A17

The aims were to examine the effects of introducing high sensitive cardiac troponin T (hs-cTnT) into clinical practice and to define at what hs-cTnT level the risk starts to increase. We included 48,594 chest pain patients at 45 SWEDEHEART centers. P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c483436d1cd2e39dfc41db177eea5379
https://doi.org/10.1016/s0735-1097(14)60017-6

Dihydropyrimidinase deficiency: Phenotype, genotype and structural consequences in 17 patients

Autor: Georg F. Hoffmann, Lawrence Greed, André B. P. van Kuilenburg, Suzanne Lind, Susanne Schubert, Antonia Ribes, Doreen Dobritzsch, Jean-François Benoist, Adrian C. Sewell, K Otfried Schwab, Raoul C.M. Hennekam, John H. Walter, Marinus Duran, Maaike de Vries, Rutger Meinsma, Jörn Oliver Sass, Gerd Kurlemann, Andreas Hahn, François Eyskens, Lida Zoetekouw, Birgit Assmann, Judith Meijer

Publikováno v: Biochimica et biophysica acta : molecular basis of disease
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1802(7-8), 639-648. Elsevier

Dihydropyrimidinase (DHP) is the second enzyme of the pyrimidine degradation pathway and catalyses the ring opening of 5,6-dihydrouracil and 5,6-dihydrothymine. To date, only 11 individuals have been reported suffering from a complete DHP deficiency.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1cc82e3f20b58422fd2c7a084f8928