Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Suzanne Lemler"'
Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers
Autor:
Julia Blievernicht, Jae-Gook Shin, Lang Li, Ulrich M. Zanger, Doo-Yeoun Cho, David A. Flockhart, Joan H.Q. Shen, Zeruesenay Desta, Todd C. Skaar, Suzanne Lemler, Kwon Bok Kim
Publikováno v:
Drug Metabolism and Pharmacokinetics. 31:107-116
The effect of rifampin on the in vivo metabolism of the antiretroviral drug efavirenz was evaluated in healthy volunteers. In a cross-over placebo control trial, healthy subjects (n = 20) were administered a single 600 mg oral dose of efavirenz after
Autor:
Vered Stearns, Daniel F. Hayes, Anna Maria Storniolo, Julie L. Otte, Janet S. Carpenter, Kevin L. Rand, Norah Lynn Henry, Jill Hayden, Anne T. Nguyen, David A. Flockhart, Stacie Jeter, Suzanne Lemler
Publikováno v:
Climacteric. 14:171-180
To evaluate the relationships among measures of hot flushes, perceived hot flush interference, sleep disturbance, and measures of quality of life while controlling for potential covariates (patient and treatment variables).Breast cancer survivors (n
Autor:
Vered Stearns, Aditya Bardia, D Cornblath, Zhen Zhang, Stacie Jeter, Anna Maria Storniolo, DA Flockhart, Norah Lynn Henry, Suzanne Lemler, G Rosson, Jill Hayden, Anne T. Nguyen, J Giles, Daniel F. Hayes, K Tarpinian
Publikováno v:
Cancer Research. 70:P2-14
Introduction: Third generation aromatase inhibitors (AIs) represent an integral part of hormonal therapy in postmenopausal women with hormone receptor (HR)-positive breast cancer. AIs are associated with musculoskeletal symptoms in up to 50% of women
Autor:
Suzanne Lemler, Jill Hayden, Lang Li, Anna Maria Storniolo, Anne Nguyen, Anne Schott, Vered Stearns, Todd C. Skaar, Jason D. Robarge, Y. Jin, David A. Flockhart, Daniel F. Hayes, Santosh Philips
Publikováno v:
Journal of Clinical Oncology. 26:5849-5854
Purpose Hot flashes are common and frequently lead to drug discontinuation among women prescribed tamoxifen. We determined whether genetic polymorphisms in estrogen receptors (ESRs) α and β (ESR1 and ESR2, respectively) are associated with tamoxife
Autor:
Bryan P. Schneider, Suzanne Lemler, Todd C. Skaar, Bradley A. Hancock, George W. Sledge, Milan Radovich, Michael Stout, Jason D. Robarge, David A. Flockhart, Anne T. Nguyen, Lang Li, Anna Maria Storniolo
Publikováno v:
Breast Cancer Research and Treatment. 111:157-163
Few studies have systematically explored a pathway approach: to test the association of multiple polymorphisms from multiple genes important to angiogenesis simultaneously with risk of breast cancer. We report our preliminary data evaluating the asso
Autor:
Janet S. Carpenter, Lang Li, Anna Maria Storniolo, Alette M. Wessels, Milan Radovich, Kathy D. Miller, David A. Flockhart, George W. Sledge, Julie L. Otte, Bryan P. Schneider, Suzanne Lemler
Publikováno v:
The Breast Journal. 17:536-538
Autor:
Daniel F. Hayes, Vered Stearns, Elizabeth Yakim, Faouzi Azzouz, Suzanne Lemler, N. Lynn Henry, Karineh Tarpinian, David A. Flockhart, Jill Hayden, Z. Desta, Anne T. Nguyen, Lang Li, Anna Maria Storniolo
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 30(9)
Purpose Aromatase inhibitors (AIs) are effective for treatment of hormone receptor–positive breast cancer, but adherence and persistence with therapy are poor. Predictors of treatment discontinuation are not clearly defined. It is unknown whether p
Autor:
Karen Kinser, Debra J Helper, Michelle Coates, Eloise Strahl, Brian W. Sipe, Douglas K. Rex, Chris Overley, Emad Y. Rahmani, Suzanne Lemler, Brody W Goodwine, Annie Lee
Publikováno v:
The American journal of gastroenterology. 97(5)
Propofol has certain advantages over benzodiazepines plus narcotics as sedation for endoscopy. In a few centers, propofol has reportedly been used in endoscopic procedures and administered by nurses supervised by gastroenterologists without attendanc
Autor:
Milan Radovich, George Sledge, Jason Robarge, Lang Li, Anna Storniolo, Suzanne Lemler, Anne Nguyen, Bradley Hancock, Michael Stout, Todd Skaar, David Flockhart
Publikováno v:
Breast Cancer Research & Treatment; Sep2008, Vol. 111 Issue 1, p157-163, 7p, 1 Diagram, 3 Charts