Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Suzanne L. Epstein"'
Autor:
Suzanne L. Epstein, Terrence M. Tumpey, Julia A. Misplon, Chia-Yun Lo, Lynn A. Cooper, Kanta Subbarao, Mary Renshaw, Suryaprakash Sambhara, Jacqueline M. Katz
Publikováno v:
Emerging Infectious Diseases, Vol 8, Iss 8, Pp 796-801 (2002)
Influenza vaccination practice, which is based on neutralizing antibodies, requires being able to predict which viral strains will be circulating. If an unexpected strain, as in the 1997 H5N1 Hong Kong outbreak, or even a pandemic emerges, appropriat
Externí odkaz:
https://doaj.org/article/4a3a8f60f1f9459f9f48048afcababab
Autor:
Stephen Mark Tompkins, Zi-Shan Zhao, Chia-Yun Lo, Julia A. Misplon, Teresa Liu, Zhiping Ye, Robert J. Hogan, Zhengqi Wu, Kimberly A. Benton, Terrence M. Tumpey, Suzanne L. Epstein
Publikováno v:
Emerging Infectious Diseases, Vol 13, Iss 3, Pp 426-426 (2007)
Changes in influenza viruses require regular reformulation of strain-specific influenza vaccines. Vaccines based on conserved antigens provide broader protection. Influenza matrix protein 2 (M2) is highly conserved across influenza A subtypes. To eva
Externí odkaz:
https://doaj.org/article/fee9914cef934acbac16c51803f85cd7
Autor:
Cécile Viboud, Katelyn Gostic, Martha I Nelson, Graeme E Price, Amanda Perofsky, Kaiyuan Sun, Nídia Sequeira Trovão, Benjamin J Cowling, Suzanne L Epstein, David J Spiro
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008583 (2020)
The prospect of universal influenza vaccines is generating much interest and research at the intersection of immunology, epidemiology, and viral evolution. While the current focus is on developing a vaccine that elicits a broadly cross-reactive immun
Externí odkaz:
https://doaj.org/article/b763a76688fc47a38f204958d5b27b02
Autor:
Janelle Rowell, Chia-Yun Lo, Graeme E Price, Julia A Misplon, Roberta L Crim, Priyanka Jayanti, Judy Beeler, Suzanne L Epstein
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215321 (2019)
Current approaches to influenza control rely on vaccines matched to viruses in circulation. Universal influenza vaccines would offer the advantage of providing broad protection against diverse strains of influenza virus. Candidate universal vaccines
Externí odkaz:
https://doaj.org/article/87d1449aa6324315822a16af8157b118
Publikováno v:
Vaccine. 39:4628-4640
Current influenza vaccines rely on inducing antibody responses to the rapidly evolving hemagglutinin (HA) and neuraminidase (NA) proteins, and thus need to be strain-matched. However, predictions of strains that will circulate are imperfect, and manu
Autor:
Santosh Dhakal, Suzanne L. Epstein, Kathleen R. Mulka, Patrick S. Creisher, Wayne Mitzner, Chia Yun Lo, Julia A. Misplon, Sharvari Deshpande, Jeffrey Loube, Sabra L. Klein
Publikováno v:
Journal of Virology
Respiratory viruses can emerge and spread rapidly before vaccines are available. It would be a tremendous advance to use vaccines that protect against whole categories of viruses, such as universal influenza vaccines, without the need to predict whic
Autor:
Suzanne L. Epstein
Publikováno v:
Gene Therapy for Diseases of the Lung ISBN: 9781003064619
Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors
Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4871f79cf6ba48c8f3af797342ed2d65
https://doi.org/10.1201/9781003064619-22
https://doi.org/10.1201/9781003064619-22
Autor:
Mark R Soboleski, Jon D Gabbard, Graeme E Price, Julia A Misplon, Chia-Yun Lo, Daniel R Perez, Jianqiang Ye, S Mark Tompkins, Suzanne L Epstein
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21937 (2011)
The rapid spread of the 2009 H1N1 pandemic influenza virus (pH1N1) highlighted problems associated with relying on strain-matched vaccines. A lengthy process of strain identification, manufacture, and testing is required for current strain-matched va
Externí odkaz:
https://doaj.org/article/ee8d2bd127e54e7fb6eecd59cc506f69
Autor:
Suzanne L. Epstein
Publikováno v:
American journal of epidemiology. 187(12)
Despite all we have learned since 1918 about influenza virus and immunity, available influenza vaccines remain inadequate to control outbreaks of unexpected strains. Universal vaccines not requiring strain matching would be a major improvement. Their