Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Suzanne L Cassel"'
Autor:
Tiffany Y Borbón, Breanna M Scorza, Gwendolyn M Clay, Fellipe Lima Nobre de Queiroz, Alan J Sariol, Jayden L Bowen, Yani Chen, Bayan Zhanbolat, Corey P Parlet, Diogo G Valadares, Suzanne L Cassel, William M Nauseef, Alexander R Horswill, Fayyaz S Sutterwala, Mary E Wilson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007247 (2019)
Cutaneous leishmaniasis (CL) is a parasitic disease causing chronic, ulcerating skin lesions. Most humans infected with the causative Leishmania protozoa are asymptomatic. Leishmania spp. are usually introduced by sand flies into the dermis of mammal
Externí odkaz:
https://doaj.org/article/d356486971d14c3ab0729d9b3e40b87f
Autor:
Ceren Ciraci, John R Janczy, Nidhi Jain, Stefanie Haasken, Cyntia Pecli E Silva, Claudia F Benjamim, Jeffrey J Sadler, Alicia K Olivier, Yoichiro Iwakura, Dmitry M Shayakhmetov, Fayyaz S Sutterwala, Suzanne L Cassel
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151252 (2016)
The precise context in which the innate immune system is activated plays a pivotal role in the subsequent instruction of CD4+ T helper (Th) cell responses. Th1 responses are downregulated when antigen is encountered in the presence of antigen-IgG imm
Externí odkaz:
https://doaj.org/article/5657ace81c584fdfa921b08750bbdbe3
Autor:
Nicole Van Groningen, Teryl K. Nuckols, Suzanne L. Cassel, Joshua M Pevnick, Galen Cook-Wiens, Aaron Kwong, Matthew Sonesen, Ray Duncan
Publikováno v:
Infection control and hospital epidemiology. 43(9)
Background:Approximately 10% of patients report allergies to penicillin, yet >90% of these allergies are not clinically significant. Patients reporting penicillin allergies are often treated with second-line, non–β-lactam antibiotics that are typi
Autor:
Kierra S. Hardy, Amanda N. Tuckey, Nicole A. Housley, Joel Andrews, Mita Patel, Abu-Bakr Al-Mehdi, Robert A. Barrington, Suzanne L. Cassel, Fayyaz S. Sutterwala, Jonathon P. Audia
Publikováno v:
Infection and Immunity. 90
Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen that causes nosocomial pneumonia, urinary tract infections, and bacteremia. A hallmark of P. aeruginosa pathogenesis is disruption of host cell function by the type III secretion syste
Autor:
Zhijun Wang, Sandrine Billet, Yoon Mee Yang, Ekihiro Seki, Michael Pimienta, Suzanne L. Cassel, Koichiro Ohashi, Stephen J. Pandol, Fayyaz S. Sutterwala, Neil A. Bhowmick, Wei Tu, Shelly C. Lu
Publikováno v:
Hepatology
Nonalcoholic fatty liver disease (NAFLD) enhances the growth and recurrence of colorectal cancer (CRC) liver metastasis. With the rising prevalence of NAFLD, a better understanding of the molecular mechanism underlying NAFLD-associated liver metastas
Publikováno v:
The Journal of Immunology. 208:51.04-51.04
Leptospirosis is a widespread zoonotic disease which can be potentially fatal in infected humans and dogs. The spirochetal bacteria Leptospira interrogans is the major causative agent of leptospirosis. Rodents serve as reservoir hosts for L. interrog
Autor:
Suzanne L. Cassel, Balaji Banoth
Publikováno v:
Translational Research. 202:52-68
Mitochondria are functionally versatile organelles. In addition to their conventional role of meeting the cell's energy requirements, mitochondria also actively regulate innate immune responses against infectious and sterile insults. Components of mi
Autor:
Moshe Arditi, Roberta A. Gottlieb, Timothy R. Crother, Yang Song, Fayyaz S. Sutterwala, Shuang Chen, Gantsetseg Tumurkhuu, Andrea Dorfleutner, Rojo A. Ratsimandresy, Malcolm Lane, Stefanie Marek-Iannucci, Suzanne L. Cassel, Jessica Carriere, Ivet Bahar, Jargalsaikhan Dagvadorj, Karolina Mikulska-Ruminska, Allen M. Andres, Christian Stehlik
Publikováno v:
Proc Natl Acad Sci U S A
The balance between NLRP3 inflammasome activation and mitophagy is essential for homeostasis and cellular health, but this relationship remains poorly understood. Here we found that interleukin-1α (IL-1α)–deficient macrophages have reduced caspas
Autor:
Jonathan Grein, Rekha Murthy, Suzanne L. Cassel, Michael Ben-Aderet, Gregory Marks, Haoshu Yang, Arnold C. Friedman, Rita Shane, Hai Tran, Sneha Krishna, Ann Duran, Meghan Madhusudhan, Ethan A. Smith, John-Ericson P. Margallo
Publikováno v:
Infection control and hospital epidemiology. 40(12)
In patients with β-lactam allergies, administration of non–β-lactam surgical prophylaxis is associated with increased risk of infection. Although many patients self-report β-lactam allergies, most are unconfirmed or mislabeled. A quality improve
Autor:
Jerrold Weiss, Suzanne L. Cassel, Fayyaz S. Sutterwala, Roberta A. Gottlieb, Eric I. Elliott, Shankar S. Iyer, Alexis N. Miller, Aleksandr Stotland, Balaji Banoth
Publikováno v:
The Journal of Immunology. 200:3047-3052
The NLRP3 inflammasome is activated in response to microbial and danger signals, resulting in caspase-1–dependent secretion of the proinflammatory cytokines IL-1β and IL-18. Canonical NLRP3 inflammasome activation is a two-step process requiring b