Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Suzanne L, Baker"'
Autor:
Theresa M. Harrison, Tyler J. Ward, Alice Murphy, Suzanne L. Baker, Pablo A. Dominguez, Robert Koeppe, Prashanthi Vemuri, Samuel N. Lockhart, Youngkyoo Jung, Danielle J. Harvey, Laura Lovato, Arthur W. Toga, Joseph Masdeu, Hwamee Oh, Darren R. Gitelman, Neelum Aggarwal, Heather M. Snyder, Laura D. Baker, Charles DeCarli, William J. Jagust, Susan M. Landau
Publikováno v:
NeuroImage, Vol 265, Iss , Pp 119761- (2023)
Accurate measurement of Alzheimer's disease (AD) pathology in older adults without significant clinical impairment is critical to assessing intervention strategies aimed at slowing AD-related cognitive decline. The U.S. Study to Protect Brain Health
Externí odkaz:
https://doaj.org/article/a0f290d012c6415f8163be639455f5c6
Autor:
Edmond Teng, Paul T. Manser, Sandra Sanabria Bohorquez, Kristin R. Wildsmith, Karen Pickthorn, Suzanne L. Baker, Michael Ward, Geoffrey A. Kerchner, Robby M. Weimer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background The role and implementation of tau PET imaging for predicting subsequent cognitive decline in Alzheimer’s disease (AD) remains uncertain. This study was designed to evaluate the relationship between baseline [18F]GTP1 tau PET an
Externí odkaz:
https://doaj.org/article/151ea849eff2427ead44ea9980aa2f28
Autor:
Theresa M. Harrison, Anne Maass, Jenna N. Adams, Richard Du, Suzanne L. Baker, William J. Jagust
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Deposition of tau protein aggregates occurs during aging and Alzheimer disease. Here, the authors show that tau burden in the anterior-temporal memory network is associated with disrupted fMRI connectivity and functional isolation of the hippocampus
Externí odkaz:
https://doaj.org/article/943d6b83e00c49b4bc60134224b62d84
Autor:
Lindsey Dobyns, Kailin Zhuang, Suzanne L. Baker, Dan Mungas, William J. Jagust, Theresa M. Harrison
Publikováno v:
Nature Aging. 3:229-237
Autor:
Ida Sonni, Orit H. Lesman Segev, Suzanne L. Baker, Leonardo Iaccarino, Deniz Korman, Gil D. Rabinovici, William J. Jagust, Susan M. Landau, Renaud La Joie, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Positron emission tomography targeting tau (tau‐PET) is a promising diagnostic tool for the identification of Alzheimer's disease (AD). Currently available data rely on quantitative measures, and a visual interpretation method
Externí odkaz:
https://doaj.org/article/c7f218404cb64730a9c4c0082d85af83
Autor:
Leonardo Iaccarino, Gautam Tammewar, Nagehan Ayakta, Suzanne L. Baker, Alexandre Bejanin, Adam L. Boxer, Maria Luisa Gorno-Tempini, Mustafa Janabi, Joel H. Kramer, Andreas Lazaris, Samuel N. Lockhart, Bruce L. Miller, Zachary A. Miller, James P. O'Neil, Rik Ossenkoppele, Howard J. Rosen, Daniel R. Schonhaut, William J. Jagust, Gil D. Rabinovici
Publikováno v:
NeuroImage: Clinical, Vol 17, Iss , Pp 452-464 (2018)
The relationships between β-amyloid (Aβ), tau and neurodegeneration within Alzheimer's Disease pathogenesis are not fully understood. To explore these associations in vivo, we evaluated 30 Aβ PET-positive patients (mean±sd age 62.4±8.3) with mil
Externí odkaz:
https://doaj.org/article/a8dda70402cc446f8048fa97782ec1b1
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 648-657 (2017)
[18F]-AV-1451 is a leading tracer used with positron emission tomography (PET) to quantify tau pathology. However, [18F]-AV-1451 shows âoff targetâ or non-specific binding, which we define as binding of the tracer in unexpected areas unlikely to ha
Externí odkaz:
https://doaj.org/article/1f78bfeb92c84500b86734aa3ed54465
Autor:
Cécile Tissot, Stijn Servaes, Firoza Z. Lussier, João Pedro Ferrari-Souza, Joseph Therriault, Pâmela C.L. Ferreira, Gleb Bezgin, Bruna Bellaver, Douglas Teixeira Leffa, Sulantha S. Mathotaarachchi, Mira Chamoun, Jenna Stevenson, Nesrine Rahmouni, Min Su Kang, Vanessa Pallen, Nina Margherita-Poltronetti, Yi-Ting Wang, Jaime Fernandez-Arias, Andrea L. Benedet, Eduardo R. Zimmer, Jean-Paul Soucy, Dana L. Tudorascu, Annie D. Cohen, Madeleine Sharp, Serge Gauthier, Gassan Massarweh, Brian Lopresti, William E. Klunk, Suzanne L. Baker, Victor L. Villemagne, Pedro Rosa-Neto, Tharick A. Pascoal
Publikováno v:
Journal of Nuclear Medicine. 64:452-459
Autor:
Anne Maass, Susan Landau, Suzanne L. Baker, Andy Horng, Samuel N. Lockhart, Renaud La Joie, Gil D. Rabinovici, William J. Jagust
Publikováno v:
NeuroImage, Vol 157, Iss , Pp 448-463 (2017)
The recent development of tau-specific positron emission tomography (PET) tracers enables in vivo quantification of regional tau pathology, one of the key lesions in Alzheimer's disease (AD). Tau PET imaging may become a useful biomarker for clinical
Externí odkaz:
https://doaj.org/article/c8f2f0e4fba14d088d776fe3fa45666f
Publikováno v:
eLife, Vol 8 (2019)
Tau pathology first appears in the transentorhinal and anterolateral entorhinal cortex (alEC) in the aging brain. The transition to Alzheimer’s disease (AD) is hypothesized to involve amyloid-β (Aβ) facilitated tau spread through neural connectio
Externí odkaz:
https://doaj.org/article/64bd885a74f94b44b48dc38832189b46