Randomized, controlled trial of lasmiditan over four migraine attacks: Findings from the CENTURION study

Autor: Erin G Doty, Uwe Reuter, Sonja M. Bragg, Timothy Smith, Sherie A. Dowsett, Judith Krikke-Workel, Qun Lin, Messoud Ashina, Suzanne Klise, John H. Krege

Publikováno v: Cephalalgia
Ashina, M, Reuter, U, Smith, T, Krikke-Workel, J, Klise, S R, Bragg, S, Doty, E G, Dowsett, S A, Lin, Q & Krege, J H 2021, ' Randomized, controlled trial of lasmiditan over four migraine attacks : Findings from the CENTURION study ', Cephalalgia, vol. 41, no. 3, pp. 294-304 . https://doi.org/10.1177/0333102421989232

Background We present findings from the multicenter, double-blind Phase 3 study, CENTURION. This study was designed to assess the efficacy of and consistency of response to lasmiditan in the acute treatment of migraine across four attacks. Methods Pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6567ac8218687f8a6f9562e38684a92
https://doi.org/10.1177/0333102421989232

Long-term safety and efficacy of lasmiditan for acute treatment of migraine: Final results of the GLADIATOR study

Autor: Michael Case, Rashna Khanna, Jan Lewis Brandes, Joel Raskin, Raghavendra Vasudeva, David Kudrow, Suzanne Klise, John H. Krege

Publikováno v: Cephalalgia Reports, Vol 3 (2020)

GLADIATOR was a prospective, randomized, open-label, phase 3 study of lasmiditan 100 mg or 200 mg dosed intermittently for up to 1 year in patients with episodic migraine. Most patients had completed one of two single-attack studies before participat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d020b0a904c83a4b320bdac40a98ad2a
https://doi.org/10.1177/2515816320958176

Urodynamic standardization in a large-scale, multicenter clinical trial examining the effects of daily tadalafil in men with lower urinary tract symptoms with or without benign prostatic obstruction

Autor: Roger R. Dmochowski, Michael E. Albo, Suzanne Klise, Lei Xu, Stephen R. Kraus, Claus G. Roehrborn

Publikováno v: Neurourology and Urodynamics. 29:741-747

Aims To present the methodology, standardization techniques, and results from post hoc test–retest reproducibility analyses for a large, placebo-controlled, multicenter trial, employing urodynamic studies (UDS) to assess the impact of daily tadalaf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d25daec735c5a5088629b3d706671e8d
https://doi.org/10.1002/nau.20825

A phase II study of abemaciclib as a monotherapy and in combination with other agents in patients with previously treated metastatic pancreatic ductal adenocarcinoma (PDAC)

Autor: Donald Thornton, Howard S. Hochster, Suzanne Klise, E. Gabriela Chiorean, Shivani Nanda

Publikováno v: Journal of Clinical Oncology. 35:TPS4150-TPS4150

TPS4150 Background: PDAC is a lethal tumor with unusual resistance to cytotoxic and targeted therapies, and pathogenesis frequently associated with hyperactive CDK 4&6 signaling. Pre-clinical models have demonstrated anti-proliferative activity with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73791d169ce7b0215a15a98508c78fc0
https://doi.org/10.1200/jco.2017.35.15_suppl.tps4150

Urodynamic Effects of Once Daily Tadalafil in Men With Lower Urinary Tract Symptoms Secondary to Clinical Benign Prostatic Hyperplasia: A Randomized, Placebo Controlled 12-Week Clinical Trial

Autor: Roger R. Dmochowski, Stephen R. Kraus, Suzanne Klise, Jed Kaminetsky, Claus G. Roehrborn, Lei Xu

Publikováno v: Journal of Urology. 189

We explored the impact of once daily tadalafil on urodynamic measures in men with lower urinary tract symptoms secondary to clinical benign prostatic hyperplasia via invasive and noninvasive urodynamic studies.We conducted a multicenter, randomized,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94cb548fe5ae1f42ae1fc14821a56e3
https://doi.org/10.1016/j.juro.2012.11.025