13C and 15N NMR evidence for peripheral intercalation of uniformly labeled fusogenic peptides incorporated in a biomimetic membrane

Autor: Prashant Agrawal, Johan Hollander, Dieter Langosch, Huub J. M. de Groot, Suzanne Kiihne

Publikováno v: Biochimica et Biophysica Acta-Biomembranes, 1768(12), 3020-3028

Membrane fusion requires drastic and transient changes of bilayer curvature and here we have studied the interaction of three de novo designed synthetic hydrophobic peptides with a biomimetic three-lipid mixture by solid state NMR. An experimental ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f40d43ff4b72e1617198424f592d68
https://doi.org/10.1016/j.bbamem.2007.09.024

Molecular Oxygen Spin–Lattice Relaxation in Solutions Measured by Proton Magnetic Relaxation Dispersion

Autor: Suzanne Kiihne, Ching Ling Teng, Robert G. Bryant, Heedoek Hong

Publikováno v: Journal of Magnetic Resonance. 148:31-34

Proton spin–lattice relaxation rate constants have been measured as a function of magnetic field strength for water, water–glycerol solution, cyclohexane, methanol, benzene, acetone, acetonitrile, and dimethyl sulfoxide. The magnetic relaxation d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de35c44a7b647b1dabcafb017b9846a6
https://doi.org/10.1006/jmre.2000.2219

Distance Measurements by Dipolar Recoupling Two-Dimensional Solid-State NMR

Autor: Suzanne Kiihne, D. M. Gregory, J. C. Shiels, J. A. Stringer, Gary P. Drobny, M. A. Mehta

Publikováno v: The Journal of Physical Chemistry A. 102:2274-2282

We present a two-dimensional NMR technique for the measurement of dipolar couplings in polycrystalline solids. This experiment is fully transverse and uses a windowless dipolar recoupling pulse sequence (DRAWS, described in Gregory, D. M.; et al. Che

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec129a6ea4a96d51396984542c85c385
https://doi.org/10.1021/jp9721412

MRI susceptometry: Image-based measurement of absolute susceptibility of MR contrast agents and human blood

Autor: Robert M. Weisskoff, Suzanne Kiihne

Publikováno v: Magnetic Resonance in Medicine. 24:375-383

We present a novel NMR imaging technique that allows absolute determination of the magnetic susceptibility constant, χ, of a solution. By comparing the phase difference of MR images produced with an instant (echo planar) “offset” spin-echo seque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1a7a9cfcf973ab415c46173d37c0725
https://doi.org/10.1002/mrm.1910240219

Solid-state NMR evidence for a protonation switch in the binding pocket of the H1 receptor upon binding of the agonist histamine

Autor: Rob Leurs, Venkata R. P. Ratnala, Willem J. DeGrip, Huub J. M. de Groot, Suzanne Kiihne, Francesco Buda

Publikováno v: Journal of the American Chemical Society, 129(4), 867-872
Journal of the American Chemical Society, 129, 867-72
Ratnala, V R, Kiihne, S R, Buda, F, Leurs, R, de Groot, H & DeGrip, W J 2007, ' Solid-state NMR evidence for a protonation switch in the binding pocket of the H1 receptor upon binding of the agonist histamine ', Journal of the American Chemical Society, vol. 129, no. 4, pp. 867-72 . https://doi.org/10.1021/ja0652262
Journal of the American Chemical Society, 129, 4, pp. 867-72
Journal of the American Chemical Society, 129(4), 867-72. American Chemical Society

Contains fulltext : 52047.pdf (Publisher’s version ) (Closed access) G protein coupled receptors (GPCRs) represent a major superfamily of transmembrane receptor proteins that are crucial in cellular signaling and are major pharmacological targets.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d1c567099847f80367b277913cc95a
https://pubmed.ncbi.nlm.nih.gov/17243823