Výsledky vyhledávání - "Suzanne Kadereit"

Akademický článek

Taking the stem cell debate to the public.

Autor: Leonard I Zon, Laurie Zoloth, Suzanne Kadereit

Publikováno v: PLoS Biology, Vol 2, Iss 6, p e188 (2004)

Externí odkaz: https://doaj.org/article/aaff2d50cc2645f786bd5a1b378cb399

Toxicity of ionizing radiation (IR) in a human induced pluripotent stem cell (hiPSC)-derived 3D early neurodevelopmental model

Autor: Patrick Hermle, Eugenia Salzmann, Alexander Reifschneider, Annemarie Klatt, Milena Korneck, Dieter Stoll, Suzanne Kadereit, Lisanne-Josephin Schneider, Alexander Bürkle

Prenatal brain development is a complex and sensitive process, highly susceptible to environmental influences such as pollutants, stress, malnutrition, drugs, tobacco exposure, or ionizing radiation (IR). Disturbances in development may cause life-lo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0d5e7ef955ad481342ebb05a01a617

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A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles

Autor: Olesja Bondarenko, Stefan Schildknecht, Stefan Mecking, Vivek Tanavde, Qian Yi Lee, Suzanne Kadereit, Marion Kapitza, Betty Tan, Marcel Leist, Benjamin Scheinhardt, Lisa Hoelting

Publikováno v: Archives of Toxicology; Vol 87
Archives of Toxicology

Nanoparticles (NPs) have been shown to accumulate in organs, cross the blood–brain barrier and placenta, and have the potential to elicit developmental neurotoxicity (DNT). Here, we developed a human embryonic stem cell (hESC)-derived 3-dimensional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222cd5fd2702bbaf0869a264f1f0a1de
https://doi.org/10.1007/s00204-012-0984-2

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Stem Cells

Autor: Benedikt Müller, Suzanne Kadereit

Publikováno v: Drug Discovery and Evaluation: Pharmacological Assays ISBN: 9783319053912

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::996f7a47d26d25f9e38545e80221cfed
https://doi.org/10.1007/978-3-319-05392-9_114

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Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing

Autor: Philipp B. Kuegler, Suzanne Kadereit, Winston Koh, Tanja Waldmann, Andreas Genewsky, Vivek Tanavde, Bastian Zimmer, Marcel Leist, Birte Baudis, Betty Tan

Publikováno v: Cell Death and Differentiation; Vol 18

As neuronal differentiation of embryonic stem cells (ESCs) recapitulates embryonic neurogenesis, disturbances of this process may model developmental neurotoxicity (DNT). To identify the relevant steps of in vitro neurodevelopment, we implemented a d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb20da22c65ff0b0f3cab0816be87a4

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Sensitivity of Dopaminergic Neuron Differentiation from Stem Cells to Chronic Low-Dose Methylmercury Exposure

Autor: Stefan Schildknecht, Suzanne Kadereit, Marcel Leist, Vivek Tanavde, Philipp B. Kuegler, Bastian Zimmer

Publikováno v: Toxicological Sciences
Toxicological Sciences; Vol 121

Perinatal exposure to low doses of methylmercury (MeHg) can cause adult neurological symptoms. Rather than leading to a net cell loss, the toxicant is assumed to alter the differentiation and neuronal functions such as catecholaminergic transmission.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9386922b0bc1d53ede12350531e90822

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GFAP-independent inflammatory competence and trophic functions of astrocytes generated from murine embryonic stem cells

Autor: Marcel Leist, Andreas Marx, Suzanne Kadereit, Bastian Zimmer, Sascha Keller, Philipp B. Kuegler, Bettina A. Baumann

Publikováno v: Glia
Glia; Vol 60

The directed generation of pure astrocyte cultures from pluripotent stem cells has proven difficult. Generation of defined pluripotent-stem-cell derived astrocytes would allow new approaches to the investigation of plasticity and heterogeneity of ast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2193bfd19eccca6ec4f622d84d89a704

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