Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Suzanne J.F. Kaptein"'
Autor:
Sapna Sharma, Michael A. Schmid, Lorena Sanchez Felipe, Jana Grenelle, Suzanne J.F. Kaptein, Lotte Coelmont, Johan Neyts, Kai Dallmeier
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 9, Pp 2196-2203 (2020)
Plasmid-launched live-attenuated vaccines (PLLAV), also called infectious DNA (iDNA) vaccines, combine the assets of genetic immunization with the potency of replication-competent live viral vaccines. However, due to their origin as bacterial plasmid
Externí odkaz:
https://doaj.org/article/5b8805ccbb5345fb9cd960384c55a83f
Autor:
Rana Abdelnabi, Caroline S. Foo, Suzanne J.F. Kaptein, Xin Zhang, Thuc Nguyen Dan Do, Lana Langendries, Laura Vangeel, Judith Breuer, Juanita Pang, Rachel Williams, Valentijn Vergote, Elisabeth Heylen, Pieter Leyssen, Kai Dallmeier, Lotte Coelmont, Arnab K. Chatterjee, Raf Mols, Patrick Augustijns, Steven De Jonghe, Dirk Jochmans, Birgit Weynand, Johan Neyts
Publikováno v:
EBioMedicine, Vol 72, Iss , Pp 103595- (2021)
Background: Favipiravir and Molnupiravir, orally available antivirals, have been reported to exert antiviral activity against SARS-CoV-2. First efficacy data have been recently reported in COVID-19 patients. Methods: We here report on the combined an
Externí odkaz:
https://doaj.org/article/2e32a0a4a1b54255ac1c5d554b84392d
Autor:
Laurens Liesenborghs, Isabel Spriet, Dirk Jochmans, Ann Belmans, Iwein Gyselinck, Laure-Anne Teuwen, Sebastiaan ter Horst, Erwin Dreesen, Tatjana Geukens, Matthias M. Engelen, Ewout Landeloos, Vincent Geldhof, Helga Ceunen, Barbara Debaveye, Bert Vandenberk, Lorenz Van der Linden, Sofie Jacobs, Lana Langendries, Robbert Boudewijns, Thuc Nguyen Dan Do, Winston Chiu, Xinyu Wang, Xin Zhang, Birgit Weynand, Thomas Vanassche, Timothy Devos, Geert Meyfroidt, Wim Janssens, Robin Vos, Pieter Vermeersch, Joost Wauters, Geert Verbeke, Paul De Munter, Suzanne J.F. Kaptein, Joana Rocha-Pereira, Leen Delang, Eric Van Wijngaerden, Johan Neyts, Peter Verhamme
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103454- (2021)
Externí odkaz:
https://doaj.org/article/a9dc46fa677a4f63b1d97aa898d674d9
Autor:
Rana Abdelnabi, Robbert Boudewijns, Caroline S. Foo, Laura Seldeslachts, Lorena Sanchez-Felipe, Xin Zhang, Leen Delang, Piet Maes, Suzanne J.F. Kaptein, Birgit Weynand, Greetje Vande Velde, Johan Neyts, Kai Dallmeier
Publikováno v:
EBioMedicine, Vol 68, Iss , Pp 103403- (2021)
Background: Within one year after its emergence, more than 108 million people acquired SARS-CoV-2 and almost 2·4 million succumbed to COVID-19. New SARS-CoV-2 variants of concern (VoC) are emerging all over the world, with the threat of being more r
Externí odkaz:
https://doaj.org/article/ee564667283f4a5b96d422846fde7095
Autor:
Laurens Liesenborghs, M.D., Isabel Spriet, Pharm.D., Dirk Jochmans, Ph.D., Ann Belmans, Ph.D., Iwein Gyselinck, M.D., Laure-Anne Teuwen, M.D., Sebastiaan ter Horst, Msc., Erwin Dreesen, Ph.D., Tatjana Geukens, M.D., Matthias M. Engelen, M.D., Ewout Landeloos, M.D., Vincent Geldhof, M.D., Helga Ceunen, Barbara Debaveye, Bert Vandenberk, M.D., Lorenz Van der Linden, Pharm.D., Sofie Jacobs, MSc., Lana Langendries, Msc., Robbert Boudewijns, Msc., Thuc Nguyen Dan Do, Msc., Winston Chiu, Msc., Xinyu Wang, Msc., Xin Zhang, Msc., Birgit Weynand, M.D., Thomas Vanassche, M.D., Timothy Devos, M.D., Geert Meyfroidt, M.D., Wim Janssens, M.D., Robin Vos, M.D., Pieter Vermeersch, M.D., Joost Wauters, M.D., Geert Verbeke, Ph.D., Paul De Munter, M.D., Suzanne J.F. Kaptein, Ph.D, Joana Rocha-Pereira, Ph.D., Leen Delang, Ph.D., Eric Van Wijngaerden, M.D., Johan Neyts, Ph.D., Peter Verhamme, M.D.
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103288- (2021)
Background: The antifungal drug itraconazole exerts in vitro activity against SARS-CoV-2 in Vero and human Caco-2 cells. Preclinical and clinical studies are required to investigate if itraconazole is effective for the treatment and/or prevention of
Externí odkaz:
https://doaj.org/article/493cb36c411d448c91da9bf02c9c911c
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2122 (2019)
In humans, Zika virus and viral RNA have been detected in semen up to 2.2 months and 6 months post infection (pi), respectively. Although the contribution of sexual transmission to the spread of ZIKV is too low to sustain an outbreak, it can increase
Externí odkaz:
https://doaj.org/article/73f3227539694bb7baac5fb345cf61e5
Autor:
Pieter Baatsen, Rana Abdelnabi, Suzanne J.F. Kaptein, Verwimp S, Sofie Jacobs, Van Mellaert L, Leen Delang, Lana Langendries
Publikováno v:
J Virol
The impact of the host microbiota on arbovirus infections is currently not well understood. Arboviruses are viruses transmitted through the bites of infected arthropods, predominantly mosquitoes or ticks. The first site of arbovirus inoculation is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188670b15492facb780c16458788de2b
https://europepmc.org/articles/PMC8941878/
https://europepmc.org/articles/PMC8941878/
Autor:
Caroline S. Foo, Rana Abdelnabi, Suzanne J.F. Kaptein, Xin Zhang, Sebastiaan ter Horst, Raf Mols, Leen Delang, Joana Rocha-Pereira, Lotte Coelmont, Pieter Leyssen, Kai Dallmeier, Valentijn Vergote, Elisabeth Heylen, Laura Vangeel, Arnab K. Chatterjee, Pieter P. Annaert, Patrick F. Augustijns, Steven De Jonghe, Dirk Jochmans, Mieke Gouwy, Seppe Cambier, Jennifer Vandooren, Paul Proost, Christine van Laer, Birgit Weynand, Johan Neyts
Publikováno v:
Antiviral research. 202
Nelfinavir is an HIV protease inhibitor that has been widely prescribed as a component of highly active antiretroviral therapy, and has been reported to exert in vitro antiviral activity against SARS-CoV-2. We here assessed the effect of Nelfinavir i
Autor:
Donald E. Ingber, H. Feldmann, Kyle Rosenke, César Muñoz-Fontela, Joana Rocha-Pereira, Pierre Stéphane Gsell, Matthew B. Frieman, Simon G. P. Funnell, Kai Dallmeier, Suzanne J.F. Kaptein, E. de Wit, Johan Neyts, Leen Delang, R. Le Grand, Pauline Maisonnasse, W. E. Dowling, G. A. Hamilton, C. M. Coleman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-4 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.4253. ⟨10.1038/s41467-020-17907-w⟩
Nature Communications, 2020, 11 (1), pp.4253. ⟨10.1038/s41467-020-17907-w⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.4253. ⟨10.1038/s41467-020-17907-w⟩
Nature Communications, 2020, 11 (1), pp.4253. ⟨10.1038/s41467-020-17907-w⟩
There is an urgent need for drugs, therapies and vaccines to be available to protect the human population against COVID-19. One of the first approaches taken in the COVID-19 global response was to consider repurposing licensed drugs. This commentary
Autor:
Suzanne J.F. Kaptein, Rabah A. T. Serya, Amr M. El-Araby, Madonna M. A. Mitry, Nermin Samir, Johan Neyts
Publikováno v:
Archives of Pharmaceutical Sciences Ain Shams University, Vol 4, Iss 2, Pp 145-180 (2020)
Flaviviridae family comprises the flavivirus genotype that represents a significant world health problem as it includes the Yellow fever virus (YFV) and Zika virus (ZIKV) which are responsible for large outbreaks and for which novel therapies are in