Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Suzanne J. Romano"'
Autor:
William Charles Ripka, Scott W. Nelson, Kevin M. Short, Michael J. Newman, Richard B. Honzatko, Karl Norvell, Frank U. Axe, Kristen L. Arienti, Deborah H. Slee, Tassie L. Collins, Todd K. Jones, Jun-young Choe, Herbert J. Fromm, Rachel Denise Anne Kimmich, Suzanne J. Romano
Publikováno v:
Journal of Biological Chemistry. 278:51176-51183
A highly constrained pseudo-tetrapeptide (OC252-324) further defines a new allosteric binding site located near the center of fructose-1,6-bisphosphatase. In a crystal structure, pairs of inhibitory molecules bind to opposite faces of the enzyme tetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea24c33701eda690081ee60805f1970
https://doi.org/10.1074/jbc.m308396200
https://doi.org/10.1074/jbc.m308396200
Publikováno v:
Journal of Neurochemistry. 68:640-648
One of the most abundant nicotinic acetylcholine receptors expressed in the central and peripheral nervous systems is a species that contains the alpha 7 gene product, binds alpha-bungarotoxin with high affinity, and has a high relative permeability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8054494182ae64a52c448593f209be3d
https://doi.org/10.1046/j.1471-4159.1997.68020640.x
https://doi.org/10.1046/j.1471-4159.1997.68020640.x
Publikováno v:
Journal of Neurobiology. 32:69-80
Several neuronal nicotinic acetylcholine receptor (AChR) genes are expressed in chick skeletal muscle during development. One of the most abundantly expressed is alpha 7, which produces a protein capable of binding alpha-bungarotoxin and is physicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98e603d9feee0ea0ad7fbd79a2af126c
https://doi.org/10.1002/(sici)1097-4695(199701)32:1<69::aid-neu7>3.0.co
https://doi.org/10.1002/(sici)1097-4695(199701)32:1<69::aid-neu7>3.0.co
Publikováno v:
Journal of Neurobiology. 29:115-125
Second messenger regulation of neuronal acetylcholine receptors (AChRs) was investigated in a mouse fibroblast cell line, M10, stably transfected with chicken alpha 4 and beta 2 cDNAs. Both forskolin and 8-bromo-cyclic adenosine 3',5'-monophosphate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef8df18466b0ff16e192b5914b94693
https://doi.org/10.1002/(sici)1097-4695(199601)29:1<115::aid-neu9>3.0.co
https://doi.org/10.1002/(sici)1097-4695(199601)29:1<115::aid-neu9>3.0.co
Autor:
Alex B. Lentsch, Fernando Lopez-Neblina, Suzanne J. Romano, Luis H. Toledo-Pereyra, Peter A. Ward, Roberto Anaya-Prado
Publikováno v:
Journal of investigative surgery : the official journal of the Academy of Surgical Research. 19(5)
The infiltration of neutrophils after ischemia and reperfusion (I/R) is facilitated by the expression of adhesion molecules on the surface of both leukocytes and endothelial cells. Adhesion molecules of the selectin family are of particular importanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea3c762e0d31be68f2064332d807b4a
https://pubmed.ncbi.nlm.nih.gov/16966210
https://pubmed.ncbi.nlm.nih.gov/16966210
Autor:
Suzanne J Romano
Publikováno v:
Treatments in Respiratory Medicine
Asthma and COPD are chronic inflammatory conditions that affect hundreds of millions of patients worldwide. New therapeutics are desperately needed, especially those that target the underlying causes and prevent disease progression. Although asthma a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5bb116e82c6a49811fe72e80ea36011
https://pubmed.ncbi.nlm.nih.gov/15813660
https://pubmed.ncbi.nlm.nih.gov/15813660
Autor:
Jinghua Yu, Judy K. John, Todd K. Jones, Neil K. Raheja, Frank U. Axe, Truc N. Nguyen, Suzanne J. Romano, William Charles Ripka, Deborah H. Slee
Publikováno v:
Journal of medicinal chemistry. 44(13)
A novel series of non-carbohydrate imidazole-based selectin inhibitors has been discovered via high-throughput screening using a P-selectin ELISA-based assay system. The initial lead 1 had an IC(50) of 17 microM in the P-selectin ELISA; this potency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4f1d924cd15d5b15efbb41621b943f
https://pubmed.ncbi.nlm.nih.gov/11405647
https://pubmed.ncbi.nlm.nih.gov/11405647
Autor:
Roderick A. Corriveau, Sukumar Vijayaraghavan, Zhong-wei Zhang, Margaret M. Rathouz, Suzanne J. Romano, William G. Conroy, Phyllis C. Pugh, Bo Huang, Darwin K. Berg
Publikováno v:
Effects of Nicotine on Biological Systems II ISBN: 9783034874472
Native acetylcholine (ACh) receptors that contain the α7 gene product function as ligand-gated ion channels that are cation-selective, prefer nicotine over ACh, and rapidly desensitize. Activation of the receptors elevates intracellular calcium leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::565e49e18e8e7ec193c850b7c5877a84
https://doi.org/10.1007/978-3-0348-7445-8_8
https://doi.org/10.1007/978-3-0348-7445-8_8
Autor:
Roderick A. Corriveau, Sukumar Vijayaraghavan, Zhong-Wei Zhang, Suzanne J. Romano, Margaret M. Rathouz, Darwin K. Berg, William G. Conroy, Phyllis C. Pugh
Publikováno v:
Muscle Relaxants ISBN: 9784431668985
Neurons can express a number of acetylcholine receptor genes simultaneously and assemble several receptor subtypes distinguished by subunit composition. One class of such receptors is largely extrasynaptic in location and contains the α7 gene produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d59bb3cf4285ed89edfda1acb274dbc
https://doi.org/10.1007/978-4-431-66896-1_17
https://doi.org/10.1007/978-4-431-66896-1_17