Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Suzanne J Litscher"'
Autor:
Jasmin Kristianto, Suzanne J Litscher, Michael G Johnson, Forum Patel, Mital Patel, Jacqueline Fisher, Ryley K Zastrow, Abigail B Radcliff, Robert D Blank
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148571 (2016)
A pleiotropic quantitative trait locus (QTL) for bone geometry and mechanical performance in mice was mapped to distal chromosome 4 via an intercross of recombinant congenic mice HcB-8 and HcB-23. To study the QTL in isolation, we have generated C3H.
Externí odkaz:
https://doaj.org/article/bdfb3e5590224be2b22bb729107c13cf
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45165 (2012)
Phenylketonuria (PKU), caused by phenylalanine (phe) hydroxylase loss of function mutations, requires a low-phe diet plus amino acid (AA) formula to prevent cognitive impairment. Glycomacropeptide (GMP), a low-phe whey protein, provides a palatable a
Externí odkaz:
https://doaj.org/article/f053d3ff78fc40d68e45021794686b39
Autor:
Michelle M. Boyd, Suzanne J. Litscher, Laura L. Seitz, Albee Messing, Tracy L. Hagemann, Lara S. Collier
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background Alexander disease (AxD) is a rare neurodegenerative disorder that is caused by dominant mutations in the gene encoding glial fibrillary acidic protein (GFAP), an intermediate filament that is primarily expressed by astrocytes. In
Externí odkaz:
https://doaj.org/article/1f287bbee59c40abaa415f56c48a0634
Autor:
Ryley K. Zastrow, Abigail B. Radcliff, Jacqueline Fisher, Suzanne J. Litscher, Jasmin Kristianto, Mital Patel, Forum Patel, Michael G. Johnson, Robert D. Blank
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148571 (2016)
PLoS ONE
PLoS ONE
A pleiotropic quantitative trait locus (QTL) for bone geometry and mechanical performance in mice was mapped to distal chromosome 4 via an intercross of recombinant congenic mice HcB-8 and HcB-23. To study the QTL in isolation, we have generated C3H.
Autor:
Robbie S. Kattappuram, Gloria E. Lopez Franco, Meghan J. Houlihan, Robert D. Blank, Ray Vanderby, Peter Demant, Neema Saless, Suzanne J. Litscher
Publikováno v:
Bone. 46:1251-1259
Skeletal fragility is an important health problem with a large genetic component. We performed a 603 animal F2 reciprocal intercross of the recombinant congenic strains HcB-8 and HcB-23 to genetically map quantitative trait loci (QTLs) for tissue-lev
Autor:
Neema Saless, Robert D. Blank, Meghan J. Houlihan, Ray Vanderby, Suzanne J. Litscher, Peter Demant, Tyriina K. O'Neil, Gloria E. Lopez Franco, Khalid Abdul Raheem, Shaan Sudhakaran
Publikováno v:
The FASEB Journal. 23:2142-2154
Despite steady progress in identifying quantitative trait loci (QTLs) for bone phenotypes, relatively little progress has been made in moving from QTLs to identifying the relevant gene. We exploited the genetic structure of recombinant congenic mouse
Autor:
Suzanne J. Litscher, Gloria E. Lopez Franco, Tyriina K. O'Neil, Robert D. Blank, Peter Demant, Michael Piette
Publikováno v:
Calcified Tissue International. 76:26-31
Dual energy X ray absorptiometry (DXA) has become a popular analytical technique in mice and other small animals. Comparative study of bone properties at different anatomical sites is an active area of study in model organisms. Such investigations re
Autor:
Gloria E. Lopez Franco, Michael Urban-Piette, Suzanne J. Litscher, Tyriina K. O'Neil, Robert D. Blank
Publikováno v:
Journal of Clinical Densitometry. 7:326-333
Many densitometric studies in mice assess bone mineral density (BMD) at specified regions of interest, often using ex vivo specimens. In the present study, we sought to determine the precision and accuracy of ex vivo densitometry of mouse bones, comp
Autor:
Gurpreet Sandhu, Zhijie Wang, Chen Yen Ooi, Robert D. Blank, Suzanne J. Litscher, Thomas D. Pugh, Naomi C. Chesler, Michael G. Johnson, Jasmin Kristianto
Publikováno v:
Journal of Biomechanical Engineering. 135
The recombinant congenic mouse strains HcB-8 and HcB-23 differ in femoral shape, size, and strength, with HcB-8 femora being more gracile, more cylindrical, weaker, and having higher Young's modulus. In previous work, we mapped a robust, pleiotropic
Autor:
John S. Kuo, Megan D. Steffen, Paul A. Clark, Clayton J. Patros, Lara S. Collier, Fausto J. Rodriguez, Suzanne J. Litscher, Ishani De, Emily Sokn
Publikováno v:
Cancer Research. 75:PR06-PR06
Current therapies for high-grade gliomas only modestly extend survival. Given that intrinsic characteristics of glioma cancer stem cells (gCSCs) make them hard to effectively target with current therapies, cells in the tumor microenvironment such as