Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Suzanne J Hodgkinson"'
Autor:
Bruce Milne Hall, giang T Tran, Nirupama eVerma, Karren ePlain, Catherine M Robinson, Masaru eNomura, Suzanne J Hodgkinson
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Antigen specific Treg are often CD4+CD25+FoxP3+T cells, with a phenotype similar to natural Treg (nTreg). It is assumed that nTreg cannot develop into an antigen specific Treg as repeated culture with IL-2 and a specific antigen does not increase the
Externí odkaz:
https://doaj.org/article/cd9c4b0e106e4f02b3b254850319bd28
Autor:
Jason Cheung, Beata Zahorowska, Michael Suranyi, Jeffrey K. W. Wong, Jason Diep, Stephen T. Spicer, Nirupama D. Verma, Suzanne J. Hodgkinson, Bruce M. Hall
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The immune response to an allograft activates lymphocytes with the capacity to cause rejection. Activation of CD4+CD25+Foxp3+T regulatory cells (Treg) can down-regulate allograft rejection and can induce immune tolerance to the allograft. Treg repres
Externí odkaz:
https://doaj.org/article/9ec5c407df9a4a2ba527e4ce261d5650
Autor:
Nirupama D. Verma, Andrew D. Lam, Christopher Chiu, Giang T. Tran, Bruce M. Hall, Suzanne J. Hodgkinson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Resting and activated subpopulations of CD4+CD25+CD127loT regulatory cells (Treg) and CD4+CD25+CD127+ effector T cells in MS patients and in healthy individuals were compared. Peripheral blood mononuclear cells isolated using Ficoll Hypaque
Externí odkaz:
https://doaj.org/article/e08842a8d1044209a7ddc91f273c3f39
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The quest to understand how allogeneic transplanted tissue is not rejected and how tolerance is induced led to fundamental concepts in immunology. First, we review the research that led to the Clonal Deletion theory in the late 1950s that has since d
Externí odkaz:
https://doaj.org/article/63316bdc9d1e43d484326c936946be51
Autor:
Bruce M. Hall, Rachael M. Hall, Giang T. Tran, Catherine M. Robinson, Paul L. Wilcox, Prateek K. Rakesh, Chuanmin Wang, Alexandra F. Sharland, Nirupama D. Verma, Suzanne J. Hodgkinson
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CD4+CD25+Foxp3+T cell population is heterogenous and contains three major sub-groups. First, thymus derived T regulatory cells (tTreg) that are naïve/resting. Second, activated/memory Treg that are produced by activation of tTreg by antigen and cyto
Externí odkaz:
https://doaj.org/article/886ca1e1c5ef4eb18f1eef7445395015
Autor:
Jason, Cheung, Beata, Zahorowska, Michael, Suranyi, Jeffrey K W, Wong, Jason, Diep, Stephen T, Spicer, Nirupama D, Verma, Suzanne J, Hodgkinson, Bruce M, Hall
Publikováno v:
Frontiers in immunology. 13
The immune response to an allograft activates lymphocytes with the capacity to cause rejection. Activation of CD4
Autor:
Nirupama D, Verma, Andrew D, Lam, Christopher, Chiu, Giang T, Tran, Bruce M, Hall, Suzanne J, Hodgkinson
Publikováno v:
Scientific Reports
Resting and activated subpopulations of CD4+CD25+CD127loT regulatory cells (Treg) and CD4+CD25+CD127+ effector T cells in MS patients and in healthy individuals were compared. Peripheral blood mononuclear cells isolated using Ficoll Hypaque were stai
Autor:
Bruce M. Hall, Karren M. Plain, Giang T. Tran, Nirupama D. Verma, Catherine M. Robinson, Masaru Nomura, Rochelle Boyd, Suzanne J. Hodgkinson
Publikováno v:
Transplant Immunology. :33-41
Autor:
Giang T, Tran, Suzanne J, Hodgkinson, Nicole, Carter, Nirupama D, Verma, Catherine M, Robinson, Karren M, Plain, Masaru, Nomura, Bruce M, Hall
Publikováno v:
Journal of neuroimmunology. 341
Experimental autoimmune neuritis (EAN) induced by peripheral nerve myelin (PNM) is self-limiting and re-immunization with PNM does not re-activate disease. This study showed inhibition of EAN by CD4
Autor:
Nirupama D, Verma, Catherine M, Robinson, Nicole, Carter, Paul, Wilcox, Giang T, Tran, Chaunmin, Wang, Alexandra, Sharland, Masaru, Nomura, Karren M, Plain, G Alexander, Bishop, Suzanne J, Hodgkinson, Bruce M, Hall
Publikováno v:
Frontiers in Immunology
Therapy with alloantigen-specific CD4+CD25+ T regulatory cells (Treg) for induction of transplant tolerance is desirable, as naïve thymic Treg (tTreg) are not alloantigen-specific and are weak suppressor cells. Naïve tTreg from DA rats cultured wit