Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Suzanne H Kim"'
Autor:
Walter G. Smith, Suzanne H Kim, Doreen Villani-Price, Matthew W Mahoney, Nayereh S Ghoreishi-Haack, Helen Y. Chen, Thomas D. Penning, Stella Siu-Tzyy Yu, James W. Malecha, Leslie J Askonas, Chi-Dean Liang, Elizabeth I Harding, E.Yvonne Pyla, Maureen K Highkin, James K. Gierse, Julie M Miyashiro, Mark A Russell, James F Kachur, Chen Barbara B
Publikováno v:
Journal of Medicinal Chemistry. 45:3482-3490
Leukotriene B(4) (LTB(4)) is a potent, proinflammatory mediator involved in the pathogenesis of a number of diseases including inflammatory bowel disease, psoriasis, rheumatoid arthritis, and asthma. The enzyme LTA(4) hydrolase represents an attracti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49aaaeb42023ad7fd78de02ecc724a97
https://doi.org/10.1021/jm0200916
https://doi.org/10.1021/jm0200916
Autor:
Thomas D. Penning, Nizal S. Chandrakumar, Barbara B. Chen, Helen Y. Chen, Bipin N. Desai, Stevan W. Djuric, Stephen H. Docter, Alan F. Gasiecki, Richard A. Haack, Julie M. Miyashiro, Mark A. Russell, Stella S. Yu, David G. Corley, Richard C. Durley, Brian F. Kilpatrick, Barry L. Parnas, Leslie J. Askonas, James K. Gierse, Elizabeth I. Harding, Maureen K. Highkin, James F. Kachur, Suzanne H. Kim, Gwen G. Krivi, Doreen Villani-Price, E. Yvonne Pyla, Walter G. Smith, Nayereh S. Ghoreishi-Haack
Publikováno v:
Journal of Medicinal Chemistry. 43:721-735
Leukotriene B(4) (LTB(4)) is a pro-inflammatory mediator that has been implicated in the pathogenesis of a number of diseases including inflammatory bowel disease (IBD) and psoriasis. Since the action of LTA(4) hydrolase is the rate-limiting step for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2c8b8f857645ec82bda0e73ed60429
https://doi.org/10.1021/jm990496z
https://doi.org/10.1021/jm990496z
Autor:
Doreen Villani-Price, Suzanne H Kim, Walter G. Smith, Leslie J Askonas, Elizabeth I Harding, Maureen K Highkin, Thomas D. Penning, Alan F. Gasiecki, Nayereh S Ghoreishi-Haack, Nizal S Chandrakumar, E.Yvonne Pyla, Bipin N Desai, James F Kachur, Mark A Russell, Stevan W Djuric, James W. Malecha, James K. Gierse, Julie M Miyashiro
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:1137-1139
The synthesis and biological evaluation of a series of heterocyclic analogues of the previously reported LTA(4) hydrolase inhibitor 1b are described. Imidazopyridine and purine analogues are specifically highlighted with several demonstrating excelle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6830ee52b64cb2d30d9d134d0185d9a9
https://doi.org/10.1016/s0960-894x(03)00039-8
https://doi.org/10.1016/s0960-894x(03)00039-8
Autor:
Maureen K Highkin, Leslie J Askonas, Doreen Villani-Price, Chi-Dean Liang, Bipin N Desai, Thomas D. Penning, James F Kachur, Elizabeth I Harding, Nayereh S Ghoreishi-Haack, Mark A Russell, Julie M Miyashiro, Walter G. Smith, E.Yvonne Pyla, Nizal S Chandrakumar, Stevan W Djuric, Suzanne H Kim, James K. Gierse, Alan F. Gasiecki
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(23)
The synthesis and biological evaluation of a series of functionalized pyrrolidine- and piperidine-containing analogues of our lead LTA(4) hydrolase inhibitor, SC-57461A, is described. A number of compounds showed excellent potency in our in vitro scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bec3c88d96d40830db918a67cb8307f
https://pubmed.ncbi.nlm.nih.gov/12419366
https://pubmed.ncbi.nlm.nih.gov/12419366
Autor:
Edward Bond
In this first volume of notebooks, Edward Bond reveals himself to be one of the finest and most creative minds to have emerged in the twentieth century. Exploring the meeting point between politics and the art of the writer, Bond's notes chart the cr
Autor:
Edward Bond
This second volume of Edward Bond's notebooks covers the period from Restoration, his historic drama with songs, to Eleven Vests, his play for young people written for Big Brum Theatre-in-Education'There is a cliché - which is also false - that all