Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Suzanne Graef"'
Autor:
Livingstone Fultang, Silvia Panetti, Margaret Ng, Paul Collins, Suzanne Graef, Nagy Rizkalla, Sarah Booth, Richard Lenton, Boris Noyvert, Claire Shannon-Lowe, Gary Middleton, Francis Mussai, Carmela De Santo
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 235-246 (2019)
Background: Targeting of MDSCs is a major clinical challenge in the era of immunotherapy. Antibodies which deplete MDSCs in murine models can reactivate T cell responses. In humans such approaches have not developed due to difficulties in identifying
Externí odkaz:
https://doaj.org/article/4484df2a46f841cf91fd257440db08ae
Autor:
Raffit Hassan, Carmela De Santo, Gary Middleton, Maryalice Stetler-Stevenson, Seth M. Steinberg, Tim F. Greten, Firouzeh Korangy, Jingli Zhang, Betsy Morrow, Constance Yuan, Bahar Guliz Yenidunya, Neha Wali, Anish Thomas, Francis Mussai, Suzanne Graef, Swati Khanna
Purpose: The cross-talk between tumor cells, myeloid cells, and T cells can play a critical role in tumor pathogenesis and response to immunotherapies. Although the etiology of mesothelioma is well understood, the impact of mesothelioma tumor cells o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da80cebd0aa2ff873220b7f01f3304f
https://doi.org/10.1158/1078-0432.c.6527363.v1
https://doi.org/10.1158/1078-0432.c.6527363.v1
Autor:
Raffit Hassan, Carmela De Santo, Gary Middleton, Maryalice Stetler-Stevenson, Seth M. Steinberg, Tim F. Greten, Firouzeh Korangy, Jingli Zhang, Betsy Morrow, Constance Yuan, Bahar Guliz Yenidunya, Neha Wali, Anish Thomas, Francis Mussai, Suzanne Graef, Swati Khanna
Mesothelioma granulocytes suppress T cell activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3b686811d98ccdcb3d7db82e38e13
https://doi.org/10.1158/1078-0432.22469825
https://doi.org/10.1158/1078-0432.22469825
Autor:
Raffit Hassan, Carmela De Santo, Gary Middleton, Maryalice Stetler-Stevenson, Seth M. Steinberg, Tim F. Greten, Firouzeh Korangy, Jingli Zhang, Betsy Morrow, Constance Yuan, Bahar Guliz Yenidunya, Neha Wali, Anish Thomas, Francis Mussai, Suzanne Graef, Swati Khanna
Supplementary Figs and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec3d9cb5436e1b966cdd801d760a28a
https://doi.org/10.1158/1078-0432.22469831
https://doi.org/10.1158/1078-0432.22469831
Autor:
Raffit Hassan, Carmela De Santo, Gary Middleton, Maryalice Stetler-Stevenson, Seth M. Steinberg, Tim F. Greten, Firouzeh Korangy, Jingli Zhang, Betsy Morrow, Constance Yuan, Bahar Guliz Yenidunya, Neha Wali, Anish Thomas, Francis Mussai, Suzanne Graef, Swati Khanna
Mesothelioma upregulates ROS production by granulocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348eed0665b25d22ecdc3168bb84f291
https://doi.org/10.1158/1078-0432.22469819.v1
https://doi.org/10.1158/1078-0432.22469819.v1
Autor:
Raffit Hassan, Carmela De Santo, Gary Middleton, Maryalice Stetler-Stevenson, Seth M. Steinberg, Tim F. Greten, Firouzeh Korangy, Jingli Zhang, Betsy Morrow, Constance Yuan, Bahar Guliz Yenidunya, Neha Wali, Anish Thomas, Francis Mussai, Suzanne Graef, Swati Khanna
Arginase activity does not drive immunosuppressive granulocyte function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae8689a41c8c1ee41bb99f920110c22
https://doi.org/10.1158/1078-0432.22469828.v1
https://doi.org/10.1158/1078-0432.22469828.v1
Autor:
Raffit Hassan, Carmela De Santo, Gary Middleton, Maryalice Stetler-Stevenson, Seth M. Steinberg, Tim F. Greten, Firouzeh Korangy, Jingli Zhang, Betsy Morrow, Constance Yuan, Bahar Guliz Yenidunya, Neha Wali, Anish Thomas, Francis Mussai, Suzanne Graef, Swati Khanna
GM-CSF drives ROS release in granulocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8d7345779e05b2263eab6915008308
https://doi.org/10.1158/1078-0432.22469816.v1
https://doi.org/10.1158/1078-0432.22469816.v1
Autor:
Theresa J. Hydes, Daniel J. Cuthbertson, Suzanne Graef, Sarah Berhane, Mabel Teng, Anna Skowronska, Pushpa Singh, Sofi Dhanaraj, Abd Tahrani, Philip J. Johnson
Publikováno v:
Clinical Therapeutics
The incidence of hepatocellular carcinoma (HCC) in the United Kingdom has increased 60% in the past 10 years. The epidemics of obesity and type 2 diabetes are contributing factors. In this article, we examine the impact of diabetes and glucose-loweri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb904dfe74a71b159c5d02ff12e24b3
http://livrepository.liverpool.ac.uk/3148041/1/ViewPageProof_CLITHE_4149.pdf
http://livrepository.liverpool.ac.uk/3148041/1/ViewPageProof_CLITHE_4149.pdf
MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers
Autor:
Gary Middleton, Nagy Rizkalla, Richard Lenton, Margaret H.L. Ng, Carmela De Santo, Livingstone Fultang, Boris Noyvert, Suzanne Graef, Claire Shannon-Lowe, Sarah Booth, Francis Mussai, Paul Collins, Silvia Panetti
Publikováno v:
EBIOMEDICINE
EBioMedicine
EBioMedicine
Background: Targeting of MDSCs is a major clinical challenge in the era of immunotherapy. Antibodies which deplete MDSCs in murine models can reactivate T cell responses. In humans such approaches have not developed due to difficulties in identifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c818af8a8891ec1135d25fcbff890c
https://doi.org/10.1016/j.ebiom.2019.08.025
https://doi.org/10.1016/j.ebiom.2019.08.025
Autor:
Carmela De Santo, Raffit Hassan, Bahar Guliz Yenidunya, Constance M. Yuan, Jingli Zhang, Neha Wali, Suzanne Graef, Swati Khanna, Betsy Morrow, Gary Middleton, Seth M. Steinberg, Francis Mussai, Anish Thomas, Tim F. Greten, Maryalice Stetler-Stevenson, Firouzeh Korangy
Publikováno v:
Clinical Cancer Research. 24:2859-2872
Purpose: The cross-talk between tumor cells, myeloid cells, and T cells can play a critical role in tumor pathogenesis and response to immunotherapies. Although the etiology of mesothelioma is well understood, the impact of mesothelioma tumor cells o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec336c839c7090fce3405b6040567cdd
https://doi.org/10.1158/1078-0432.ccr-17-3757
https://doi.org/10.1158/1078-0432.ccr-17-3757