Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Suzanne Gillies"'
Autor:
Krystyna Maciaszek, Suzanne Gillies, Sawaeng Kawichai, Tippawan Prapamontol, Teetawat Santijitpakdee, Wissanupong Kliengchuay, Narut Sahanavin, William Mueller, Sotiris Vardoulakis, Pawitrabhorn Samutrtai, John W Cherrie, David M Brown, Kraichat Tantrakarnapa, Helinor J Johnston
Publikováno v:
Environmental Research: Health, Vol 1, Iss 2, p 025002 (2022)
Chiang Mai (Thailand) experiences severe haze pollution in the dry season (December–April) each year mainly due to local and regional biomass burning (e.g. of agricultural land). A major component of the haze is airborne particulate matter (PM). Du
Externí odkaz:
https://doaj.org/article/390e9fcb0ea44e9e9d5d8eed15f93508
Autor:
Suzanne Gillies, Rachel Verdon, Vicki Stone, David M. Brown, Theodore Henry, Lang Tran, Carl Tucker, Adriano G. Rossi, Charles R. Tyler, Helinor J. Johnston
Publikováno v:
Gillies, S, Verdon, R, Stone, V, Brown, D M, Henry, T, Tran, L, Tucker, C S, Rossi, A G, Tyler, C R & Johnston, H J 2022, ' Transgenic zebrafish larvae as a non-rodent alternative model to assess pro-inflammatory (neutrophil) responses to nanomaterials ', Nanotoxicology, vol. 16, no. 3, pp. 333-354 . https://doi.org/10.1080/17435390.2022.2088312
Hazard studies for nanomaterials (NMs) commonly assess whether they activate an inflammatory response. Such assessments often rely on rodents, but alternative models are needed to support the implementation of the 3Rs principles. Zebrafish (Danio rer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2495dedad06cb88f2f654be0bbb0a1f6
Autor:
David M. Brown, Vicki Stone, Adriano G. Rossi, Rachel Verdon, Suzanne Gillies, C. Lang Tran, Helinor Jane Johnston, Charles R. Tyler, Theodore B. Henry
Publikováno v:
Verdon, R, Gillies, S L, Brown, D M, Henry, T, Tran, L, Tyler, C R, Rossi, A G, Stone, V & Johnston, H J 2020, ' Neutrophil activation by nanomaterials in vitro: comparing strengths and limitations of primary human cells with those of an immortalized (HL-60) cell line. ', Nanotoxicology, pp. 1-20 . https://doi.org/10.1080/17435390.2020.1834635
Assessment of nanomaterial (NM) induced inflammatory responses has largely relied on rodent testing via measurement of leukocyte accumulation in target organs. Despite observations that NMs activate neutrophil driven inflammatory responses in vivo, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3699a80a65180d6e2273f47a5fa007ce
https://www.pure.ed.ac.uk/ws/files/186309018/Published_Version.pdf
https://www.pure.ed.ac.uk/ws/files/186309018/Published_Version.pdf
Autor:
Rachel Verdon, Charles R. Tyler, Lang Tran, Helinor Jane Johnston, Adriano G. Rossi, Vicki Stone, David M. Brown, Carl S. Tucker, Theodore B. Henry, Suzanne Gillies, Teresa F. Fernandes
Publikováno v:
Johnston, H J, Verdon, R, Gillies, S, Brown, D M, Fernandes, T F, Henry, T B, Rossi, A G, Tran, L, Tucker, C, Tyler, C R & Stone, V 2017, ' Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to nanomaterials ', Critical reviews in toxicology, pp. 1-20 . https://doi.org/10.1080/10408444.2017.1404965
Assessing the safety of engineered nanomaterials (NMs) is paramount to the responsible and sustainable development of nanotechnology, which provides huge societal benefits. Currently, there is no evidence that engineered NMs cause detrimental health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f40af2aed1b3f1fa7e217b698adbcb8
https://doi.org/10.1080/10408444.2017.1404965
https://doi.org/10.1080/10408444.2017.1404965