Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells

Autor: Nathalie R. Reinhard, Eloise C. Anthony, Peter L. Hordijk, Suzanne F. G. van Helden, Theodorus W. J. Gadella, Taofei Yin, Yi I. Wu, Joachim Goedhart

Publikováno v: Scientific Reports
Scientific reports, 6. Nature Publishing Group
Scientific Reports, 6:25502. Nature Publishing Group
Scientific Reports, 6. Nature Publishing Group
Reinhard, N R, van Helden, S F, Anthony, E C, Yin, T, Wu, Y I, Goedhart, J, Gadella, T W J & Hordijk, P L 2016, ' Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells ', Scientific Reports, vol. 6 . https://doi.org/10.1038/srep25502

Endothelial cells line the vasculature and are important for the regulation of blood pressure, vascular permeability, clotting and transendothelial migration of leukocytes and tumor cells. A group of proteins that that control the endothelial barrier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2db1611904903967f23dc0cf80b99e6
https://pubmed.ncbi.nlm.nih.gov/27147504

Podosome regulation by Rho GTPases in myeloid cells

Autor: Suzanne F. G. van Helden, Peter L. Hordijk

Publikováno v: van Helden, S F G & Hordijk, P L 2011, ' Podosome regulation by Rho GTPases in myeloid cells ', European Journal of Cell Biology, vol. 90, no. 2-3, pp. 189-197 . https://doi.org/10.1016/j.ejcb.2010.05.008

Myeloid cells form a first tine of defense against infections. They migrate from the circulation to the infected tissues by adhering to and subsequently crossing the vascular wall. This process requires precise control and proper regulation of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e2f200dd19ec0e5709ecaf9ac127d9
https://doi.org/10.1016/j.ejcb.2010.05.008

A Critical Role for Prostaglandin E2 in Podosome Dissolution and Induction of High-Speed Migration during Dendritic Cell Maturation

Autor: Carl G. Figdor, Reinier Raymakers, Daniëlle J. E. B. Krooshoop, Karin M. Broers, Suzanne F. G. van Helden, Frank N. van Leeuwen

Publikováno v: Scopus-Elsevier
ResearcherID
Journal of Immunology, 177, 1567-74
Journal of Immunology, 177, 3, pp. 1567-74

Contains fulltext : 50414.pdf (Publisher’s version ) (Closed access) Dendritic cells (DCs) are professional APCs of the immune system that play a key role in regulating T cell-based immunity. The capacity of DCs to activate T cells depends on their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b904f41b4f93f45723fecf6287cbd9d
https://doi.org/10.4049/jimmunol.177.3.1567

Human and murine model cell lines for dendritic cell biology evaluated

Autor: Suzanne F. G. van Helden, Carl G. Figdor, Frank N. van Leeuwen

Publikováno v: Immunology Letters, 117, 2, pp. 191-7
Immunology Letters, 117, 191-7

Contains fulltext : 69950.pdf (Publisher’s version ) (Closed access) Dendritic cells (DCs) are specialized antigen presenting cells that link innate and adaptive immune responses. As key mediators of T cell dependent immunity, DCs are considered pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942b4296c6b9612b3140d8ba81d1e6b3
https://doi.org/10.1016/j.imlet.2008.02.003