Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Suzanne F. C. Miller-Delaney"'
Autor:
Caroline M. Curtin, Brenton Cavanagh, Isabella Bray, Jason M. Shohet, Olga Piskareva, Ying J Tan, John Nolan, Ciara Gallagher, Ross Conlon, Harry Harvey, Suzanne F. C. Miller-Delaney, Fergal J. O'Brien, Ahmad Zaki Asraf, Larissa Deneweth, Raymond L. Stallings
Publikováno v:
Acta Biomaterialia. 70:84-97
3D scaffold-based in vitro cell culturing is a recent technological advancement in cancer research bridging the gap between conventional 2D culture and in vivo tumours. The main challenge in treating neuroblastoma, a paediatric cancer of the sympathe
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14565 (2011)
The development of different brain regions involves the coordinated control of proliferation and cell fate specification along and across the neuraxis. Here, we identify Plxdc2 as a novel regulator of these processes, using in ovo electroporation and
Externí odkaz:
https://doaj.org/article/0792a31e5c5544caaa3d8bc237ba687e
Autor:
Eva M. Jimenez-Mateos, James P. Reynolds, Suzanne F. C. Miller-Delaney, Fang Bian, An Zhou, Li Cao, David C. Henshall, Mariana Alves
Brief, non-harmful seizures (preconditioning) can temporarily protect the brain against prolonged, otherwise injurious seizures. Following focal-onset status epilepticus (SE) in preconditioned (tolerance) and sham-preconditioned (injury) mice, we scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ddf5ae0c4b3aeceadf5fc9b1ff62cb
https://europepmc.org/articles/PMC5505805/
https://europepmc.org/articles/PMC5505805/
Autor:
James P. Reynolds, Suzanne F. C. Miller-Delaney, Ross C. McKiernan, David C. Henshall, Ryder P. Gwinn, Sudipto Das, Kenneth Bryan, Raymond L. Stallings, Isabella Bray
Publikováno v:
Brain. 138:616-631
Temporal lobe epilepsy is associated with large-scale, wide-ranging changes in gene expression in the hippocampus. Epigenetic changes to DNA are attractive mechanisms to explain the sustained hyperexcitability of chronic epilepsy. Here, through methy
Autor:
Mireille Lerner-Natoli, Tobias Engel, Suzanne F. C. Miller-Delaney, Zuzanna Michalak, David C. Henshall, Takanori Sano
Publikováno v:
Epilepsy Research. 103:167-179
Mesial temporal lobe epilepsy (MTLE) is the most common, intractable seizure disorder in adults. Blood-brain barrier (BBB) disruption, including interruption of endothelial tight cell junctions and serum protein and immunoglobulin G (IgG) extravasati
Autor:
Eva M. Jimenez-Mateos, Patrick G. Buckley, Takanori Sano, Raymond L. Stallings, David C. Henshall, Sudipto Das, Suzanne F. C. Miller-Delaney, Kenneth Bryan
Publikováno v:
The Journal of Neuroscience. 32:1577-1588
Prolonged seizures (status epilepticus) produce pathophysiological changes in the hippocampus that are associated with large-scale, wide-ranging changes in gene expression. Epileptic tolerance is an endogenous program of cell protection that can be a
Autor:
Suzanne F. C. Miller-Delaney, David C. Henshall, Roger P. Simon, Eva M. Jimenez-Mateos, Ross C. McKiernan, James P. Reynolds, Takanori Sano
Publikováno v:
Frontiers in Neurology, Vol 6 (2015)
Frontiers in Neurology
Frontiers in Neurology
Exposure of the brain to brief, non-harmful seizures can activate protective mechanisms that temporarily generate a damage-refractory state. This process, termed epileptic tolerance, is associated with large-scale down-regulation of gene expression.
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1067
Epigenetic modification of DNA by methylation of the cytosine present in CG dinucleotides constitutes a key regulatory mechanism in the control of gene expression in neurological diseases. In this chapter, we describe an in-depth methodology of methy
Publikováno v:
Methods in Molecular Biology ISBN: 9781627036061
Epigenetic modification of DNA by methylation of the cytosine present in CG dinucleotides constitutes a key regulatory mechanism in the control of gene expression in neurological diseases. In this chapter, we describe an in-depth methodology of methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dacfb5013c46e872950cf72c9e700449
https://doi.org/10.1007/978-1-62703-607-8_7
https://doi.org/10.1007/978-1-62703-607-8_7
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14565 (2011)
PLoS ONE
PLoS ONE
The development of different brain regions involves the coordinated control of proliferation and cell fate specification along and across the neuraxis. Here, we identify Plxdc2 as a novel regulator of these processes, using in ovo electroporation and