Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Suzanne E. Neumueller"'
Autor:
Suzanne E. Neumueller, Nicole Buiter, Grace Hilbert, Kirstyn Grams, Reiauna Taylor, John Desalvo, Grace L. Hodges, Madeline M. Hodges, Lawrence G. Pan, Stephen J. Lewis, Hubert V. Forster, Matthew R. Hodges
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Synthetic opioids like fentanyl have improved the standard of care for many patients in the clinical setting, but their abuse leads to tens of thousands of overdose deaths annually. The current opioid epidemic underscores a critical need for insights
Externí odkaz:
https://doaj.org/article/f35bb9de2fbc465fa17838ae0f53da22
Glutamate receptor plasticity in brainstem respiratory nuclei following chronic hypercapnia in goats
Autor:
Nicholas J. Burgraff, Suzanne E. Neumueller, Kirstyn J. Buchholz, Matthew R. Hodges, Lawrence Pan, Hubert V. Forster
Publikováno v:
Physiological Reports, Vol 7, Iss 8, Pp n/a-n/a (2019)
Abstract Patients that retain CO2 in respiratory diseases such as chronic obstructive pulmonary disease (COPD) have worse prognoses and higher mortality rates than those with equal impairment of lung function without hypercapnia. We recently characte
Externí odkaz:
https://doaj.org/article/e182d2fb16d743218fad2476869da3b8
Autor:
Kirstyn J, Buchholz, Suzanne E, Neumueller, Nicholas J, Burgraff, Matthew R, Hodges, Lawrence, Pan, Hubert V, Forster
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 133(5)
Chronic hypercapnia (CH) is a hallmark of chronic lung disease, and CH increases the risk for acute-on-chronic exacerbations leading to greater hypoxemia/hypercapnia and poor health outcomes. However, the role of hypercapnia per se (duration and seve
Autor:
Kirstyn J. Buchholz, Suzanne E. Neumueller, Nicholas J. Burgraff, Matthew R. Hodges, Lawrence Pan, Hubert V. Forster
Publikováno v:
Journal of Applied Physiology. 133:1106-1118
Moderate levels of chronic hypercapnia (CH; ∼70 mmHg) in healthy adult female goats elicited similar steady-state physiological adaptations compared with mild CH (∼55 mmHg). However, unlike mild CH, moderate CH chronically suppressed acute CO2/[H
Autor:
Thomas M, Langer, Suzanne E, Neumueller, Emma, Crumley, Nicholas J, Burgraff, Sawan, Talwar, Matthew R, Hodges, Lawrence, Pan, Hubert V, Forster
Publikováno v:
Respiratory physiologyneurobiology. 239
Pulmonary ventilation (V̇I) in awake and sleeping goats does not change when antagonists to several excitatory G protein-coupled receptors are dialyzed unilaterally into the ventral respiratory column (VRC). Concomitant changes in excitatory neuromo
Autor:
Hubert V, Forster, Katie L, Krause, Tom, Kiner, Suzanne E, Neumueller, Josh M, Bonis, Baogang, Qian, Lawrence G, Pan
Publikováno v:
Advances in experimental medicine and biology. 669
Abrupt destruction of70% of the pre-Bötzinger complex (preBötzC) in awake goats results in terminal apnea (Wenninger et al. 2004b). Herein we report data on awake and sleeping goats in which the preBötzC was incrementally destroyed by injection of