Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Suzanne E. Clark"'
Autor:
Yongzhong Wei, Carlos M. Ferrario, John P. Thyfault, Suzanne E. Clark, Adam Whaley-Connell, E. Matthew Morris, Jamal A. Ibdah, Grace M. Uptergrove, James R. Sowers
Publikováno v:
Journal of Hepatology. 49:417-428
Background/Aims Non-alcoholic fatty liver disease (NAFLD) is a common health problem and includes a spectrum of hepatic steatosis, steatohepatitis and fibrosis. The renin–angiotensin system (RAS) plays a vital role in blood pressure regulation and
Autor:
Grace M. Uptergrove, James R. Sowers, Suzanne E. Clark, Carlos M. Ferrario, Yongzhong Wei, Kemin Chen, Javad Habibi, Craig S. Stump, Adam Whaley-Connell
Publikováno v:
Hypertension. 50:384-391
Reduced insulin sensitivity is characteristic of various pathological conditions such as type 2 diabetes mellitus and hypertension. Angiotensin II, acting through its angiotensin type 1 receptor, inhibits the actions of insulin in the vasculature whi
Publikováno v:
Crop Science. 45:1868-1876
There are two barley (Hordeum vulgare L.) β-amylase genes encoding important starch-degrading enzymes. The endosperm-specific β-amylase (Bmy1), the more abundant isozyme in cereal seeds, has been thoroughly characterized. The lesser abundant β-amy
Publikováno v:
Plant Physiology and Biochemistry. 41:798-804
Differences in extractable β-amylase (1,4-α-D-glucan maltohydrolase, EC 3.2.1.2) activities exist between enzymes from malt and feed barleys (Hordeum vulgare L.). Others have documented few differences in the β-amylase (bmy1) gene coding regions a
Publikováno v:
Protein Expression and Purification. 18:20-26
alpha-Glucosidases (EC 3.2.1.20) are recognized as important in starch degradation during cereal seed germination. A barley (Hordeum vulgare) alpha-glucosidase expressed in Pichia pastoris was cultured in flasks; however, the yield was low necessitat
Autor:
James R. Sowers, Wenhan Li, Suzanne E. Clark, Carlos M. Ferrario, Yongzhong Wei, Craig S. Stump
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 294(2)
Reduced insulin sensitivity is a key factor in the pathogenesis of type 2 diabetes and hypertension. Skeletal muscle insulin resistance is particularly important for its major role in insulin-mediated glucose disposal. Angiotensin II (ANG II) is inte
Autor:
E. Matthew Morris, Camila Manrique, Yongzhong Wei, James R. Sowers, Ravi Nistala, Grace M. Uptergrove, Craig S. Stump, Heping Gong, Nicholas M. Szary, Suzanne E. Clark
Publikováno v:
The Journal of biological chemistry. 281(46)
The renin-angiotensin system (RAS) and reactive oxygen species (ROS) have been implicated in the development of insulin resistance and its related complications. There is also evidence that angiotensin II (Ang II)-induced generation of ROS contribute
Publikováno v:
Treatments in endocrinology. 4(6)
The risk of cardiovascular disease (CVD) in patients with diabetes mellitus is increased more than 3-fold and is the major cause of mortality and morbidity in diabetic patients. Historically, diabetes has been considered an inadequate insulin respons
Autor:
David J. Eide, Suzanne E. Clark, Charissa D. Ellis, Colin W. MacDiarmid, Thomas J. Lyons, Fudi Wang
Publikováno v:
The Journal of Cell Biology
In this report, we show that zinc is required for endoplasmic reticulum function in Saccharomyces cerevisiae. Zinc deficiency in this yeast induces the unfolded protein response (UPR), a system normally activated by unfolded ER proteins. Msc2, a memb
Publikováno v:
Protein engineering, designselection : PEDS. 17(3)
The thermostability of alpha-glucosidase is important because the conversion of starch to fermentable sugars during the industrial production of beer and fuel ethanol typically occurs at relatively high temperatures (60-75 degrees C). Barley (Hordeum