Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Suzanne E. McKenna"'
Autor:
David S. Warner, Brian E. Mace, Daniel T. Laskowitz, John R. Lynch, Haichen Wang, Ellen Bennett, Stephen B. Leinenweber, Suzanne E. McKenna, Michael P. Vitek
Publikováno v:
Experimental Neurology. 192:109-116
Although apolipoprotein E4 (APOE4) was initially identified as a susceptibility gene for the development of Alzheimer's disease, the presence of the APOE4 allele is also associated with poor outcome after acute brain injury. One mechanism by which ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06b93a9d7cf8188d6d11429914f7e2d
https://doi.org/10.1016/j.expneurol.2004.11.014
https://doi.org/10.1016/j.expneurol.2004.11.014
Publikováno v:
Neuroscience & Biobehavioral Reviews. 23:325-336
Our understanding of the neurochemical and neuroendocrine systems' regulating the display of offensive intermale aggression has progressed substantially over the past twenty years. Pharmacological studies have shown that serotonin, via its action at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a476ab04bfb2769caf283be2c893a9
https://doi.org/10.1016/s0149-7634(98)00034-7
https://doi.org/10.1016/s0149-7634(98)00034-7
Publikováno v:
Endocrinology. 139:1594-1601
The androgen receptor (AR) is generally considered an autoregulated protein. However, studies in brain have produced mixed results regarding sex differences, which should be present given the higher endogenous levels of androgens in males, and the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7de895f10588ab7f4de23ea2027fbec
https://doi.org/10.1210/endo.139.4.5863
https://doi.org/10.1210/endo.139.4.5863
Publikováno v:
Annals of the New York Academy of Sciences. 794:8-17
There are multiple pathways involved in the regulation of male typical aggression by T, and the functional pathway is determined by genotype. Target-tissue sensitivity to the aggression-promoting properties of T and its estrogenic and androgenic meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d943bc82057ecb0625a3f4cda80a555
https://doi.org/10.1111/j.1749-6632.1996.tb32505.x
https://doi.org/10.1111/j.1749-6632.1996.tb32505.x
Autor:
Suzanne E. McKenna, Neal G. Simon
Publikováno v:
Physiology & Behavior. 54:167-170
The lordotic behavior of ovariectomized CD1 and SW female mice was tested in response to estradiol benzoate(EB)+progesterone (P) or EB + 5 alpha-dihydroprogesterone (DHP) to determine (i) the role of progestin metabolism in the regulation of sexually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e921733ba79acb30ff9a2780572a9e32
https://doi.org/10.1016/0031-9384(93)90060-s
https://doi.org/10.1016/0031-9384(93)90060-s
Autor:
Arlene A. Tan, Michael P. Vitek, Jason E. Beare, Nicholas A. Kaufman, Michael R. Hoane, Suzanne E. McKenna
Publikováno v:
Behavioural brain research. 214(2)
COG1410, a small, novel ApoE-mimetic peptide derived from the receptor binding region of apolipoprotein E (ApoE), has been classified as anti-inflammatory in nature and improves motor, sensorimotor, and cognitive dysfunction following cortical contus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a87c4f2a00d8c00304d5791b1bcaf1
https://pubmed.ncbi.nlm.nih.gov/20600347
https://pubmed.ncbi.nlm.nih.gov/20600347
Publikováno v:
Hormones and Behavior. 26:536-544
Ovariectomized CFW mice were treated with tamoxifen (TAM) alone or in combination with estradiol benzoate (EB) to determine its ability to promote/block lordotic behavior and the induction of hypothalamic progestin receptors (PR). Across a range of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::043add6e1b8518e91af03de596613bf2
https://doi.org/10.1016/0018-506x(92)90020-v
https://doi.org/10.1016/0018-506x(92)90020-v
Publikováno v:
Journal of neurotrauma. 26(1)
We have previously shown that a single dose of COG1410, a small molecule ApoE-mimetic peptide derived from the apolipoprotein E (ApoE) receptor binding region, improves sensorimotor and motor outcome following cortical contusion injury (CCI). The pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054a236ce2400f31ecac1d226eb50edf
https://pubmed.ncbi.nlm.nih.gov/19119914
https://pubmed.ncbi.nlm.nih.gov/19119914
Autor:
Pingping Song, Suzanne E. McKenna, Haichen Wang, Michael P. Vitek, Nolan Yeung, Daniel T. Laskowitz, Dale J. Christensen, Lori Durham
Publikováno v:
Journal of neurotrauma. 24(7)
Traumatic brain injury (TBI) is a silent epidemic affecting approximately 1.4 million Americans annually, at an estimated annual cost of $60 billion in the United States alone. Despite an increased understanding of the pathophysiology of closed head
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6361b14481a847866aa98f643d8b69
https://pubmed.ncbi.nlm.nih.gov/17610350
https://pubmed.ncbi.nlm.nih.gov/17610350
Autor:
Nicholas D. Birky, Jeremy L. Pierce, Michael P. Vitek, Suzanne E. McKenna, Michael R. Hoane, Tan Dang, Michael A. Holland
Publikováno v:
Journal of neurotrauma. 24(7)
It has previously been shown that small peptide molecules derived from the apolipoprotein E (ApoE) receptor binding region are anti-inflammatory in nature and can improve outcome following head injury. The present study evaluated the preclinical effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b5b775255945d6cf3226b10aa39f12
https://pubmed.ncbi.nlm.nih.gov/17610351
https://pubmed.ncbi.nlm.nih.gov/17610351