Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Suzanne E, Brett"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Vascular T-type Ca2+ channels (CaV3.1 and CaV3.2) play a key role in arterial tone development. This study investigated whether this conductance is a regulatory target of angiotensin II (Ang II), a vasoactive peptide that circulates and whic
Externí odkaz:
https://doaj.org/article/303109c026ad425cb293f8870ac61ba9
Autor:
Paulina M Kowalewska, Jacob Fletcher, William F Jackson, Suzanne E Brett, Michelle SM Kim, Galina Yu Mironova, Nadia Haghbin, David M Richter, Nathan R Tykocki, Mark T Nelson, Donald G Welsh
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 42:1693-1706
Cerebral blood flow is a finely tuned process dependent on coordinated changes in arterial tone. These changes are strongly tied to smooth muscle membrane potential and inwardly rectifying K+ (KIR) channels are thought to be a key determinant. To elu
Autor:
Galina Y. Mironova, Miguel M‐A Baudel, Victor A. Flores‐Tamez, Suzanne E. Brett, Manuel F. Navedo, Donald G. Welsh
Publikováno v:
The FASEB Journal. 36
Autor:
Shaun L. Sandow, Bjørn Olav Hald, Donald G. Welsh, Maria Sancho, Sergio Fabris, Suzanne E. Brett, Tamie L. Poepping
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 39:1072-1087
Objective— Inward rectifying K + (K IR ) channels are present in cerebral arterial smooth muscle and endothelial cells, a tandem arrangement suggestive of a dynamic yet undiscovered role for this channel. This study defined whether distinct pools o
Autor:
Mario Kassmann, Sean M. Wilson, Ahmed M. Hashad, Maik Gollasch, Jose L. Puglisi, Donald G. Welsh, Monica Romero, Osama F. Harraz, Suzanne E. Brett
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:2371-2381
Objective— This study examined whether caveolae position Ca V 3.2 (T-type Ca2+ channel encoded by the α-3.2 subunit) sufficiently close to RyR (ryanodine receptors) for extracellular Ca 2+ influx to trigger Ca 2+ sparks and large-conductance Ca 2+
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Vascular T-type Ca2+ channels (CaV3.1 and CaV3.2) play a key role in arterial tone development. This study investigated whether this conductance is a regulatory target of angiotensin II (Ang II), a vasoactive peptide that circulates and which is loca
Autor:
Maria, Sancho, Sergio, Fabris, Bjorn O, Hald, Suzanne E, Brett, Shaun L, Sandow, Tamie L, Poepping, Donald G, Welsh
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 39(6)
Objective- Inward rectifying K
Autor:
Maria Sancho, Bjørn Olav Hald, Donald G. Welsh, Suzanne E. Brett, Sean P. Marrelli, Nina Samson, Ahmed M. Hashad
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:2171-2184
The conducted vasomotor response reflects electrical communication in the arterial wall and the distance signals spread is regulated by three factors including resident ion channels. This study defined the role of inward-rectifying K+channels (KIR) i
Autor:
Suzanne E. Brett, Maria Sancho, Donald G. Welsh, Anil Zechariah, Neil Mazumdar, Rania E. Mufti
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:2571-2578
Objective— The myogenic response is central to blood flow regulation in the brain. Its induction is tied to elevated cytosolic [Ca 2+ ], a response primarily driven by voltage-gated Ca 2+ channels and secondarily by Ca 2+ wave production. Although
Autor:
Ahmed M, Hashad, Osama F, Harraz, Suzanne E, Brett, Monica, Romero, Mario, Kassmann, Jose L, Puglisi, Sean M, Wilson, Maik, Gollasch, Donald G, Welsh
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 38(10)
Objective- This study examined whether caveolae position Ca