Výsledky vyhledávání - "Suzanne Droesch"

Genetic Polymorphism of CYP2C19 Gene in the Stanislas Cohort. A link with Inflammation

Autor: A. Thompson, Suzanne Droesch, Dorothee Foernzler, Céline Bertrand-Thiebault, Gérard Siest, Bérangère Marie, Sophie Visvikis-Siest, Hind Berrahmoune

Publikováno v: Annals of Human Genetics. 72:178-183

CYP2C19, a member of the cytochrome P450 family, metabolises arachidonic acid to produce epoxyeicosanoid acids, which are involved in vascular tone and inflammation. Thus, this study describes the possible relationship between a CYP2C19 polymorphism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fe8e48b5a6603ee55b4dd62319f24b
https://doi.org/10.1111/j.1469-1809.2007.00417.x

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Autor: Daniel Lambert, Sophie Visvikis, Anne Ponthieux, Bernard Herbeth, Suzanne Droesch

Publikováno v: Clinical Chemistry. 49:1544-1546

Intercellular adhesion molecule-1 (ICAM-1) and E-, P-, and L-selectin are cellular adhesion molecules involved in the recruitment of leukocytes on the activated vessel wall during inflammation (1) and play an important role in the early stages of ath

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5dd8282feff477394385ad2efa104f9
https://doi.org/10.1373/49.9.1544

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P-selectin polymorphisms' influences on P-selectin serum concentrations and on their familial correlation: the STANISLAS family study

Autor: Bérangère Marie, Suzanne Droesch, Daniel Lambert, David-Alexandre Trégouët, Bernard Herbeth, Jean-Brice Marteau, Sophie Visvikis-Siest

Publikováno v: Journal of thrombosis and haemostasis : JTH. 6(6)

Summary. Background: P-selectin is an adhesion molecule known to be involved in the pathogenesis of several diseases through its major role in the initial phase of leukocytes recruitment during inflammation. However, genetic characterization of solub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed45fb9eb3282a0c9f7b47f6cbd1257b
https://pubmed.ncbi.nlm.nih.gov/18363816

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Biological variations, genetic polymorphisms and familial resemblance of TNF-alpha and IL-6 concentrations: STANISLAS cohort

Autor: Suzanne Droesch, Nadia Haddy, Sophie Visvikis, Catherine Sass, Sandy Maumus, Daniel Lambert, Bérangère Marie, Gérard Siest

Publikováno v: European Journal of Human Genetics
European Journal of Human Genetics, Nature Publishing Group, 2005, 13 (1), pp.109-17. ⟨10.1038/sj.ejhg.5201294⟩
European Journal of Human Genetics, 2005, 13 (1), pp.109-17. ⟨10.1038/sj.ejhg.5201294⟩

Cytokines are involved in the development of several inflammatory diseases and atherosclerosis. Their variations in healthy individuals are not well defined. The aims of this study were: firstly, to identify factors affecting biological variation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6ec32d230c7896feb9731c7604431e
https://hal.archives-ouvertes.fr/hal-00176667

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IL-6, TNF-alpha and atherosclerosis risk indicators in a healthy family population: the STANISLAS cohort

Autor: Daniel Lambert, Nadia Haddy, Gérard Siest, Suzanne Droesch, Catherine Sass, Sophie Visvikis, Mohamed Zaiou, Anne Ponthieux

Publikováno v: Atherosclerosis
Atherosclerosis, Elsevier, 2003, 170 (2), pp.277-83. ⟨10.1038/sj.ejhg.5200864⟩
Atherosclerosis, 2003, 170 (2), pp.277-83. ⟨10.1038/sj.ejhg.5200864⟩

There are no satisfactory data on circulating concentrations of inflammatory cytokines and their potential relationship with traditional and nontraditional atherosclerosis risk factors in a large healthy young population. The present study was conduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9029af7aae143e4fa955c5344f7f53
https://hal.archives-ouvertes.fr/hal-00176481

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Association between Gly241Arg ICAM-1 gene polymorphism and serum sICAM-1 concentration in the Stanislas cohort

Autor: Sophie Visvikis, Michèle Pfister, Suzanne Droesch, Daniel Lambert, Anne Ponthieux, Bernard Herbeth

Publikováno v: European journal of human genetics : EJHG. 11(9)

Intracellular adhesion molecule-1 (ICAM-1), a cellular adhesion molecule that mediates the interaction of activated endothelial cells with leukocytes, is involved in various inflammatory and cardiovascular disorders. The relation between these marker

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f10feb43d5ae5cecedaebb5886f12fdb
https://pubmed.ncbi.nlm.nih.gov/12939654

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Biological determinants of serum ICAM-1, E-selectin, P-selectin and L-selectin levels in healthy subjects: the Stanislas study

Autor: Daniel Lambert, Anne Ponthieux, Suzanne Droesch, Sophie Visvikis, Nadia Haddy, Bernard Herbeth

Publikováno v: Atherosclerosis
Atherosclerosis, Elsevier, 2004, 172 (2), pp.299-308. ⟨10.1016/j.atherosclerosis.2003.11.003⟩
Atherosclerosis, 2004, 172 (2), pp.299-308. ⟨10.1016/j.atherosclerosis.2003.11.003⟩

Background: Circulating levels of adhesion molecules increase in various inflammation-related diseases, such as atherosclerosis. However, data about factors influencing their concentrations in physiological conditions are scarce. Methods: We have stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf67f960b32b32a1405e7204b3d072f
https://pubmed.ncbi.nlm.nih.gov/15019540

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Inhibition of vitamin B12 metabolism by OH-cobalamin c-lactam in rat oligodendrocytes in culture: a model for studying neuropathy due to vitamin B12 deficiency

Autor: F Barbé, Delphine Gaire, Daniel Lambert, Jean-Pierre Nicolas, Isabelle Sponne, Suzanne Droesch, Sally P. Stabler, Robert H. Allen

Publikováno v: Neuroscience letters. 288(3)

Vitamin B12 is implicated in methylation processes. Myelin basic protein is methylated on one arginine group. A defect in methylation could produce an unstable protein, leading to neurological disorders. In order to study myelin basic protein, we hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c97dd3126e7d598880a4b3d23ad6ec
https://pubmed.ncbi.nlm.nih.gov/10889340

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Human haptocorrin in hepatocellular carcinoma

Autor: Parache Rm, F. Boisson, J. P. Nicolas, Philippe Gérard, Suzanne Droesch, Migeon C, S. Fremont, Nodari F

Publikováno v: Cancer Detection and Prevention
Cancer Detection and Prevention, Elsevier, 1999, 23 (2), pp.89-96. ⟨10.1046/j.1525-1500.1999.09914.x⟩

This study aimed to determine whether haptocorrin (HC), a vitamin B12 binder, is stored in hepatic cells and whether this storage is modified by hepatic carcinogenesis. It was carried out using immunohistochemistry on different liver tissues (normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63791c3c2e1b76ec005432e2e2950946
https://pubmed.ncbi.nlm.nih.gov/10101589

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Comparison of two methods for the measurement of rat liver methylmalonyl-coenzyme A mutase activity: HPLC and radioisotopic assays

Autor: Isabelle Sponne, Suzanne Droesch, Delphine Gaire, Aline Charlier, Jean-Pierre Nicolas, Daniel Lambert

Publikováno v: The Journal of nutritional biochemistry. 10(1)

Methylmalonyl-coenzyme A mutase (MCM) is a 5'-deoxyadenosylcobalamin-linked mitochondrial enzyme that catalyzes the isomerization of L-methylmalonyl-coenzyme A to succinyl-coenzyme A. In vitro assays of total and holo-MCM activities are important too

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb90b5af2f0b5068334b5033dac9fab
https://pubmed.ncbi.nlm.nih.gov/15539251

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