Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Suzanne Cole"'
Autor:
Terri V. Cornforth, Nathifa Moyo, Suzanne Cole, Emily P. S. Lam, Tatiana Lobry, Ron Wolchinsky, Angharad Lloyd, Katarzyna Ward, Eleanor M. Denham, Giulia Masi, Phyllis Tea Qing Yun, Colin Moore, Selsabil Dhaouadi, Gurdyal S. Besra, Natacha Veerapen, Patricia T. Illing, Julian P. Vivian, Jeremy M. Raynes, Jérôme Le Nours, Anthony W. Purcell, Samit Kundu, Jonathan D. Silk, Luke Williams, Sophie Papa, Jamie Rossjohn, Duncan Howie, Joseph Dukes
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMajor histocompatibility complex class-1-related protein (MR1), unlike human leukocyte antigen (HLA) class-1, was until recently considered to be monomorphic. MR1 presents metabolites in the context of host responses to bacterial infection.
Externí odkaz:
https://doaj.org/article/8f539e9eaf5e40e19fbc3e2c06f07574
Autor:
Sophie Papa, Luke Williams, Joseph Dukes, Jamie Rossjohn, Jonathan D Silk, Suzanne Cole, Emily Lam, Samit Kundu, Katarzyna Ward, Duncan Howie, Terri V Cornforth, Nathifa Moyo, Tatiana Lobry, Ron Wolchinsky, Angharad Lloyd, Eleanor M Denham, Gurdyal S Besra, Patricia Illing, Bruce MacLachlan, Julian Vivian, Jeremy Raynes, Jerome Le Nours, Anthony Purcell
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d7d61dd8f23b40c19240771e3414c4c9
Publikováno v:
Thyroid Research, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Background The thyroid gland is an uncommon site for metastatic deposits from non-thyroid malignancies, occurring in only 1.4 - 3% of surgical specimens where malignancy is suspected. It is even rarer for the source of thyroid metastases to
Externí odkaz:
https://doaj.org/article/ef8f5249a9cb42cc86f4c8497da0da38
Autor:
Frank Penkava, Martin Del Castillo Velasco-Herrera, Matthew D. Young, Nicole Yager, Lilian N. Nwosu, Arthur G. Pratt, Alicia Lledo Lara, Charlotte Guzzo, Ash Maroof, Lira Mamanova, Suzanne Cole, Mirjana Efremova, Davide Simone, Andrew Filer, Chrysothemis C. Brown, Andrew L. Croxford, John D. Isaacs, Sarah Teichmann, Paul Bowness, Sam Behjati, M. Hussein Al-Mossawi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Psoriatic arthritis (PsA) commonly affects patients with skin psoriasis, but its pathogenesis is still unclear. Here the authors use two types of single-cells data, mass cytometry and RNA sequencing, to describe the expansion and diversity of synovia
Externí odkaz:
https://doaj.org/article/41e60fd553ac455d9a90df903aa0ed85
Autor:
Jonathan E. Schoenhals, BS, Osama Mohamad, MD, PhD, Alana Christie, MS, Yuanyuan Zhang, MD, PhD, Daniel Li, MD, Nirmish Singla, MD, MSCS, Isaac Bowman, MD, Waddah Arafat, MD, Hans Hammers, MD, Kevin Courtney, MD, PhD, Suzanne Cole, MD, Aditya Bagrodia, MD, Vitaly Margulis, MD, Neil Desai, MD, Aurelie Garant, MD, Hak Choy, MD, Robert Timmerman, MD, James Brugarolas, MD, PhD, Raquibul Hannan, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 5, Pp 100692- (2021)
Purpose: Oligoprogression, defined as limited sites of progression on systemic therapy, in patients with metastatic renal cell carcinoma (mRCC) is not uncommon, possibly because of inter- and intratumoral heterogeneity. We evaluated the effect of ste
Externí odkaz:
https://doaj.org/article/d3d6725df09840e68eee2bfa7aa552b3
Autor:
Suzanne Cole, Janine Murray, Catherine Simpson, Remi Okoye, Kerry Tyson, Meryn Griffiths, Dominique Baeten, Stevan Shaw, Asher Maroof
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for inducing IL-17 production in other human immune subsets remains incompletely understood. Mucosal associated invariant T (MAIT) cells uniformly express retin
Externí odkaz:
https://doaj.org/article/9977591d4c7042d0b21fe34563635126
Autor:
Chad K. Porter, Mark S. Riddle, Renee M. Laird, Matthew Loza, Suzanne Cole, Christina Gariepy, Ashley Alcala, Ramiro Gutierréz, Frédéric Baribaud, Navin L. Rao, Sunil Nagpal
Publikováno v:
Contemporary Clinical Trials Communications, Vol 17, Iss , Pp - (2020)
Purpose: The etiology of several autoimmune disorders, including rheumatoid arthritis, remains unknown. While there are clear phases of disease progression, the mechanisms of transition between these phases are poorly understood. Additionally, treatm
Externí odkaz:
https://doaj.org/article/034a39954cfc48f6999d521469598135
Autor:
Annabelle Small, Suzanne Cole, Jing J. Wang, Sunil Nagpal, Ling-Yang Hao, Mihir D. Wechalekar
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 3, p 535 (2022)
Primary Sjögren’s syndrome (SjS) is an inflammatory autoimmune disorder which targets the lacrimal and salivary glands, resulting in glandular dysfunction. Currently, the immune drivers of SjS remain poorly understood and peripheral biomarkers of
Externí odkaz:
https://doaj.org/article/27def70639894b7e969f5a412e2f8886
Autor:
Suzanne Cole, Alice Walsh, Xuefeng Yin, Mihir D. Wechalekar, Malcolm D. Smith, Susanna M. Proudman, Douglas J. Veale, Ursula Fearon, Costantino Pitzalis, Frances Humby, Michele Bombardieri, Amy Axel, Homer Adams, Christopher Chiu, Michael Sharp, John Alvarez, Ian Anderson, Loui Madakamutil, Sunil Nagpal, Yanxia Guo
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-14 (2018)
Abstract Background Plasmablasts and plasma cells play a key role in many autoimmune diseases, such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). This study was undertaken to evaluate the potential of targeting CD38 as a plasma
Externí odkaz:
https://doaj.org/article/36023e7ad5564381815500c7e7f37e9e
Autor:
Bonnie van Wilgenburg, Iris Scherwitzl, Edward C. Hutchinson, Tianqi Leng, Ayako Kurioka, Corinna Kulicke, Catherine de Lara, Suzanne Cole, Sirijitt Vasanawathana, Wannee Limpitikul, Prida Malasit, Duncan Young, Laura Denney, STOP-HCV consortium, Michael D. Moore, Paolo Fabris, Maria Teresa Giordani, Ye Htun Oo, Stephen M. Laidlaw, Lynn B. Dustin, Ling-Pei Ho, Fiona M. Thompson, Narayan Ramamurthy, Juthathip Mongkolsapaya, Christian B. Willberg, Gavin R. Screaton, Paul Klenerman
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Mucosal Associated Invariant T cells have been implicated in response to bacterial pathogens. Here the authors show that in human viral infections, these cells are activated by IL-18 in cooperation with other pro-inflammatory cytokines, producing int
Externí odkaz:
https://doaj.org/article/cc3459afe5a047aa8c5feb665511a1eb