Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Suzanne Chau"'
Autor:
Melusine Bleu, Fanny Mermet-Meillon, Verena Apfel, Louise Barys, Laura Holzer, Marianne Bachmann Salvy, Rui Lopes, Inês Amorim Monteiro Barbosa, Cecile Delmas, Alexandra Hinniger, Suzanne Chau, Markus Kaufmann, Simon Haenni, Karolin Berneiser, Maria Wahle, Ivana Moravec, Alexandra Vissières, Tania Poetsch, Erik Ahrné, Nathalie Carte, Johannes Voshol, Elisabeth Bechter, Jacques Hamon, Marco Meyerhofer, Dirk Erdmann, Matteo Fischer, Therese Stachyra, Felix Freuler, Sascha Gutmann, César Fernández, Tobias Schmelzle, Ulrike Naumann, Guglielmo Roma, Kate Lawrenson, Cristina Nieto-Oberhuber, Amanda Cobos-Correa, Stephane Ferretti, Dirk Schübeler, Giorgio Giacomo Galli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Lineage-restricted transcription factor PAX8 is oncogenic in ovarian cancer cells. Here the authors show that PAX8 interacts and recruits a splice variant of the MECOM locus PRDM3 to control the gene expression module involved in adhesion and extrace
Externí odkaz:
https://doaj.org/article/e459f346777c48fab385e6b2235f6c4c
Autor:
Johannes Voshol, Therese Stachyra, Alexandra Vissieres, Elisabeth Bechter, Verena Apfel, Erik Ahrné, Maria Wahle, Suzanne Chau, Ivana Moravec, Karolin Fiona Berneiser, Nathalie Carte, Tania Poetsch, Rui Lopes, Dirk Schübeler, Simon Haenni, Markus Kaufmann, Stephane Ferretti, Dirk Erdmann, Alexandra Hinniger, Marianne Bachmann Salvy, Jacques Hamon, Guglielmo Roma, Amanda Cobos-Correa, Ulrike Naumann, César Fernández, Louise Barys, Cristina Nieto-Oberhuber, Giorgio G. Galli, Melusine Bleu, Matteo Fischer, Felix Freuler, Sascha Gutmann, Kate Lawrenson, Fanny Mermet-Meillon, Tobias Schmelzle, Cecile Delmas, Laura Holzer, Marco Meyerhofer, Ines Barbosa
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The transcription factor PAX8 is critical for the development of the thyroid and urogenital system. Comprehensive genomic screens furthermore indicate an additional oncogenic role for PAX8 in renal and ovarian cancers. While a plethora of PAX8-regula
Autor:
François Gessier, Robert Mah, Philipp Holzer, Therese-Marie Stachyra, Andrea Vaupel, Vito Guagnano, Emmanuelle Wirth, Patrick Chène, Pascal Furet, Joseph Schoepfer, Aude Izaac, Bahaa Salem, Stefan Stutz, Joerg Kallen, Keiichi Masuya, Achim Schlapbach, Suzanne Chau
Publikováno v:
ChemMedChem. 14(14)
Hdm2 (human MDM2, human double minute 2 homologue) counteracts p53 function by direct binding to p53 and by ubiquitin-dependent p53 protein degradation. Activation of p53 by inhibitors of the p53-Hdm2 interaction is being pursued as a therapeutic str
Autor:
Aude Izaac, Stefan Stutz, Patrick Chène, Emmanuelle Wirth, Achim Schlapbach, Keiichi Masuya, François Gessier, Robert Mah, Bahaa Salem, Andrea Vaupel, Therese-Marie Stachyra, Philipp Holzer, Vito Guagnano, Joseph Schoepfer, Pascal Furet, Joerg Kallen, Suzanne Chau
Publikováno v:
ChemMedChem. 14:1304-1304