Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Suzanne C. Edavettal"'
Autor:
Stephen R. Johnson, Dianlin Xie, Lihong Cheng, Yang Hong, John S. Tokarski, Adriana Zupa-Fernandez, Jodi K. Muckelbauer, Mark R. Witmer, Sophie Wu, Chiehying Chang, Donna L. Pedicord, Suzanne C. Edavettal, David S. Weinstein, William J. Pitts, Yuval Blat, James R. Burke, Lisa Elkin, Kristen Pike, Jeffrey Tredup
Publikováno v:
Journal of Biological Chemistry. 290:11061-11074
Inhibition of signal transduction downstream of the IL-23 receptor represents an intriguing approach to the treatment of autoimmunity. Using a chemogenomics approach marrying kinome-wide inhibitory profiles of a compound library with the cellular act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9176c99caf70572ecd7615a142c06a
https://doi.org/10.1074/jbc.m114.619502
https://doi.org/10.1074/jbc.m114.619502
Autor:
Lee Warren, Suzanne C. Edavettal, Jacob Marcus, Matthew G. Stanton, Hugh Nuthall, David L. Sloman, Tammy Dellovade, Alexander A. Szewczak, Deborah Walker, Sanjeev Munshi, Andrea C. Mislak, Michael Hutton, Michael D. Altman, Zhenhua Wu, Mansuo Hayashi, Dapeng Chen, Hua-Poo Su, Njamkou Noucti
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(17)
Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer’s disease. This manuscript outlines efforts to optimize a pyrazolopyrimidine series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7ecae5b310e12910bfeea4ba9e5416
https://pubmed.ncbi.nlm.nih.gov/27491711
https://pubmed.ncbi.nlm.nih.gov/27491711
Autor:
James F. Parsons, Michael L. Doyle, Aaron P. Yamniuk, Suzanne C. Edavettal, Edward Eisenstein, Kelly Calabrese, Satya P. Yadav, S. Bergqvist
Publikováno v:
Journal of biomolecular techniques : JBT. 23(3)
Protein–protein interactions identified through high-throughput proteomics efforts continue to advance our understanding of the protein interactome. In addition to highly specific protein–protein interactions, it is becoming increasingly more com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9083008eb549312af73abe831059ca17
https://pubmed.ncbi.nlm.nih.gov/22942790
https://pubmed.ncbi.nlm.nih.gov/22942790
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 841
Obtaining diffraction quality crystals is frequently an iterative process which traditionally has involved screening large numbers of crystallization conditions. Due to advances in high-throughput gene engineering, recombinant expression, and purific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::479228433ad643a74e753b8ff355071f
https://pubmed.ncbi.nlm.nih.gov/22222447
https://pubmed.ncbi.nlm.nih.gov/22222447
Publikováno v:
Protein Expression and Purification
The demands of structural and functional genomics for large quantities of soluble, properly folded proteins in heterologous hosts have been aided by advancements in the field of protein production and purification. Escherichia coli, the preferred hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f940821eca2c60ae5bc4ec3629a64ac2
https://pubmed.ncbi.nlm.nih.gov/16084395
https://pubmed.ncbi.nlm.nih.gov/16084395
Autor:
Suzanne C. Edavettal, Joe M. Krahn, Andrea F. Moon, Robert J. Linhardt, Masahiko Negishi, Eva Muñoz, Lars C. Pedersen, Jian Liu
Publikováno v:
The Journal of biological chemistry. 279(43)
Heparan sulfate (HS) plays essential roles in assisting herpes simplex virus infection and other biological processes. The biosynthesis of HS includes numerous specialized sulfotransferases that generate a variety of sulfated saccharide sequences, co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbedf0a098f554ef060fc4ac5089566a
https://pubmed.ncbi.nlm.nih.gov/15304505
https://pubmed.ncbi.nlm.nih.gov/15304505
Autor:
Kevin Carrick, Jian Liu, Suzanne C. Edavettal, R. Marshall Pope, Alexander Tropsha, Lars C. Pedersen, Ruchir R. Shah
Publikováno v:
Biochemistry. 43(16)
The 3-O-sulfation of glucosamine by heparan sulfate 3-O-sulfotransferase-1 (3-OST-1) is a key modification step during the biosynthesis of anticoagulant heparan sulfate (HS). In this paper, we present evidence of a conformational change that occurs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d52212fc2f8e7f6ee3fa7a95bb3a14
https://pubmed.ncbi.nlm.nih.gov/15096036
https://pubmed.ncbi.nlm.nih.gov/15096036
Autor:
Suzanne C. Edavettal, Robert J. Linhardt, Jian Liu, Karen A. Lee, Lars C. Pedersen, Masahiko Negishi
Heparan sulfate interacts with antithrombin, a protease inhibitor, to regulate blood coagulation. Heparan sulfate 3-O-sulfotransferase isoform 1 performs the crucial last step modification in the biosynthesis of anticoagulant heparan sulfate. This en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fdaad71c203d57100ae697993222b01
