Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Suzanne C Crawley"'
Autor:
Susan K Lyman, Suzanne C Crawley, Ruoyu Gong, Joanne I Adamkewicz, Garth McGrath, Jason Y Chew, Jennifer Choi, Charles R Holst, Leanne H Goon, Scott A Detmer, Jana Vaclavikova, Mary E Gerritsen, Robert A Blake
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17692 (2011)
BackgroundMany proteins that are dysregulated or mutated in cancer cells rely on the molecular chaperone HSP90 for their proper folding and activity, which has led to considerable interest in HSP90 as a cancer drug target. The diverse array of HSP90
Externí odkaz:
https://doaj.org/article/f3255661be8a49999d93ff431dca0903
Autor:
Jer-Yuan Hsu, Daniel D. Kaplan, Marco Colonna, Martina Molgora, Jie Tang, Chun Chu, Bin Fan, Raj Haldankar, Shelley R. Starck, Avantika Kekatpure, Bernard B. Allan, Mark J. Solloway, Yan Wang, Jian Luo, Wenhui Liu, Lee B. Rivera, Christina Song, Joshua S. Lichtman, Zhen Zhang, Kalyani Mondal, Alan K. Kutach, Wei Guo, Geoffrey Horner, Nikolai A. Sharkov, Seth Malmersjö, Hung-I H. Chen, Betty Li, Suzanne C. Crawley, Richard Ventura, Kyle P. O'Hollaren, Peirong Chen, Vicky Y. Lin, Julie M. Roda, Kevin J. Paavola
Suppressive myeloid cells inhibit antitumor immunity by preventing T-cell responses. Immunoglobulin-like transcript 3 (ILT3; also known as LILRB4) is highly expressed on tumor-associated myeloid cells and promotes their suppressive phenotype. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee65685feee404b324e236abb336418
https://doi.org/10.1158/2326-6066.c.6550622.v1
https://doi.org/10.1158/2326-6066.c.6550622.v1
Autor:
Jer-Yuan Hsu, Daniel D. Kaplan, Marco Colonna, Martina Molgora, Jie Tang, Chun Chu, Bin Fan, Raj Haldankar, Shelley R. Starck, Avantika Kekatpure, Bernard B. Allan, Mark J. Solloway, Yan Wang, Jian Luo, Wenhui Liu, Lee B. Rivera, Christina Song, Joshua S. Lichtman, Zhen Zhang, Kalyani Mondal, Alan K. Kutach, Wei Guo, Geoffrey Horner, Nikolai A. Sharkov, Seth Malmersjö, Hung-I H. Chen, Betty Li, Suzanne C. Crawley, Richard Ventura, Kyle P. O'Hollaren, Peirong Chen, Vicky Y. Lin, Julie M. Roda, Kevin J. Paavola
Supplementary Table from The Fibronectin–ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4823249fced34ebf362c1215b91917e4
https://doi.org/10.1158/2326-6066.22544372
https://doi.org/10.1158/2326-6066.22544372
Autor:
Jer-Yuan Hsu, Daniel D. Kaplan, Marco Colonna, Martina Molgora, Jie Tang, Chun Chu, Bin Fan, Raj Haldankar, Shelley R. Starck, Avantika Kekatpure, Bernard B. Allan, Mark J. Solloway, Yan Wang, Jian Luo, Wenhui Liu, Lee B. Rivera, Christina Song, Joshua S. Lichtman, Zhen Zhang, Kalyani Mondal, Alan K. Kutach, Wei Guo, Geoffrey Horner, Nikolai A. Sharkov, Seth Malmersjö, Hung-I H. Chen, Betty Li, Suzanne C. Crawley, Richard Ventura, Kyle P. O'Hollaren, Peirong Chen, Vicky Y. Lin, Julie M. Roda, Kevin J. Paavola
Supplementary Figure from The Fibronectin–ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6301a3bfd56081293466fffb65b11a
https://doi.org/10.1158/2326-6066.22544375
https://doi.org/10.1158/2326-6066.22544375
Autor:
Peirong Chen, Suzanne C. Crawley, Vicky Y. Lin, Varun Kapoor, Kevin J. Paavola, Hung-I Chen, Joshua S. Lichtman, Betty Li, Kalyani Mondal, Alan K. Kutach, Yan Wang, Daniel D. Kaplan, Julie M. Roda
Publikováno v:
Cancer Research. 82:LB216-LB216
Suppressive myeloid cells inhibit antitumor immunity by preventing T cell responses. Immunoglobulin-like transcript 3 (ILT3, also known as LILRB4) is highly expressed on tumor-associated myeloid cells and promotes their suppressive phenotype. Our tea
Autor:
Susan K. Lyman, Suzanne C. Crawley, Ruoyu Gong, Joanne I. Adamkewicz, Garth McGrath, Jason Y. Chew, Jennifer Choi, Charles R. Holst, Leanne H. Goon, Scott A. Detmer, Jana Vaclavikova, Mary E. Gerritsen, Robert A. Blake
Publikováno v:
PLoS ONE, Vol 6, Iss 3 (2011)
Externí odkaz:
https://doaj.org/article/2f45722322f6416e9d86caf0046a9f63
Autor:
Eun Taek Park, Juan Engel, Ching Ching Leow, Wei-Qiang Gao, Sanjay Kakar, James R. Gum, Young Sam Kim, Suzanne C. Crawley, Hee Kyung Oh
Publikováno v:
Clinical Cancer Research. 12:5403-5410
Purpose: Mucinous cancers and signet ring carcinomas are distinct classes of colon cancers characterized by their production of copious quantities of intestinal goblet cell mucin, MUC2. Deletion of transcription factor HATH1 ablates the biogenesis of
Autor:
Dae-Ho Ahn, Ryota Hokari, Jian Dong Li, Shingo Kato, Young Sam Kim, Stacey C. Yang, Suzanne C. Crawley
Publikováno v:
Cellular Physiology and Biochemistry. 15:029-040
The molecular mechanisms responsible for TNF-alpha-mediated MUC2 intestinal mucin up-regulation in HM3 colon adenocarcinoma cells were analyzed using promoter-reporter assays of the 5'-flanking region of the MUC2 gene. Chemical inhibitors, mutant rep
Autor:
James R. Gum, James W. Hicks, Suzanne C. Crawley, Stacey C. Yang, Alexander D. Borowsky, Christine M. Dahl, Sanjay Kakar, Dong Hoon Kim, Robert D. Cardiff, Young S. Kim
Publikováno v:
Molecular Cancer Research. 2:504-513
The colonic epithelium contains three major types of mature cells, namely, absorptive, goblet, and enteroendocrine cells. These cells are maintained by a complex process of cell renewal involving progenitor and stem cells, and colon cancers develop w