Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Suzanne B. Buck"'
Autor:
Brandon S.J. Davies, Shao H. Yang, Emily Farber, Roger Lee, Suzanne B. Buck, Douglas A. Andres, H. Peter Spielmann, Brian J. Agnew, Fuyuhiko Tamanoi, Loren G. Fong, Stephen G. Young
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 1, Pp 126-134 (2009)
Hutchinson-Gilford progeria syndrome (HGPS) is caused by the synthesis of a truncated prelamin A, commonly called progerin, that contains a carboxyl-terminal farnesyl lipid anchor. The farnesyl lipid anchor helps to target progerin to membrane surfac
Externí odkaz:
https://doaj.org/article/cddf26965f54443bbf2973c17e3a768f
Publikováno v:
BioTechniques, Vol 44, Iss 7, Pp 927-929 (2008)
The 5-bromo-2′-deoxyuridine (BrdU) labeling of cells followed by antibody staining has been the standard method for direct measurement of cells in the S-phase. Described is an improved method for the detection of S-phase cell cycle progression base
Externí odkaz:
https://doaj.org/article/7287dc1ccc76495c92ad6fee0e78b743
Autor:
Loren G. Fong, Douglas A. Andres, Suzanne B. Buck, H. Peter Spielmann, Stephen G. Young, Shao H. Yang, Brian Agnew, Brandon S.J. Davies, Roger Lee, Emily Farber, Fuyuhiko Tamanoi
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 1, Pp 126-134 (2009)
Hutchinson-Gilford progeria syndrome (HGPS) is caused by the synthesis of a truncated prelamin A, commonly called progerin, that contains a carboxyl-terminal farnesyl lipid anchor. The farnesyl lipid anchor helps to target progerin to membrane surfac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a13df35d03f10c555b6bdc31ddc3fc
http://www.sciencedirect.com/science/article/pii/S0022227520414762
http://www.sciencedirect.com/science/article/pii/S0022227520414762
Publikováno v:
Journal of Medicinal Chemistry. 47:696-702
The unsubstituted, 3'-Cl, 4'-C1, and 3',4'-diCl C10 analogues of cryptophycin-24 were prepared via total synthesis and tested in vitro for cytotoxicity against MCF-7 and multi-drug-resistant MCF-7/ADR breast cancer cell lines and in a tubulin assembl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb04e5fe27558e816f43bcfeb894a5a
https://doi.org/10.1021/jm030278c
https://doi.org/10.1021/jm030278c
Autor:
Syed M. Ali, Emily A. Reiff, Gunda I. Georg, Craig J. Mossman, MariJean Eggen, Suzanne B. Buck, Laxminarayan Bhat, Thomas C. Boge, Sajiv K. Nair
Publikováno v:
The Journal of Organic Chemistry. 65:7792-7799
Two efficient protocols for the synthesis of tert-butyl (5S,6R,2E, 7E)-5-[(tert-butyldimethylsilyl)oxy]-6-methyl-8-phenyl-2, 7-octadienoate, a major component of the cryptophycins, are reported. The first utilized the Noyori reduction and Frater alky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d0daca9684a5b15516988e5b43587d8
https://doi.org/10.1021/jo000767+
https://doi.org/10.1021/jo000767+
Publikováno v:
Journal of Medicinal Chemistry. 47:3697-3699
Epi-C3-cryptophycin-24, epi-C3-m-chlorobenzyl-cryptophycin-24, and the corresponding styrenes were synthesized and tested in vitro against the MCF-7 and multidrug-resistant MCF-7/ADR breast cancer cell lines and in an in vitro tubulin assembly assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d2c68f441534cee5064b6568a562e4
https://doi.org/10.1021/jm030555f
https://doi.org/10.1021/jm030555f
Autor:
Dale L. Boger, Brian G. Lawhorn, Mark R. Swingle, Pukar Ratti, Richard E. Honkanen, Lauren Amable, Christopher P. Burke, Suzanne B. Buck, Kimberly L. Fischer
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 331(1)
Fostriecin and cytostatin are structurally related natural inhibitors of serine/threonine phosphatases, with promising antitumor activity. The total synthesis of these antitumor agents has enabled the production of structural analogs, which are usefu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4977a3b2624068564fc79ddeb9ff8f
https://pubmed.ncbi.nlm.nih.gov/19592665
https://pubmed.ncbi.nlm.nih.gov/19592665
Autor:
Courtenay R. Hart, Suzanne B. Buck, Jessica F. Dweck, Linda C. Hsieh-Wilson, Peter M. Clark, Daniel E. Mason, Brian J. Agnew, Eric C. Peters
We report an advanced chemoenzymatic strategy for the direct fluorescence detection, proteomic analysis, and cellular imaging of O-GlcNAc-modified proteins. O-GlcNAc residues are selectively labeled with fluorescent or biotin tags using an engineered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d6f16ee069d682e3b37e7630a544d7
https://resolver.caltech.edu/CaltechAUTHORS:20150519-144346544
https://resolver.caltech.edu/CaltechAUTHORS:20150519-144346544
Publikováno v:
BioTechniques. 44(7)
The 5-bromo-2′-deoxyuridine (BrdU) labeling of cells followed by antibody staining has been the standard method for direct measurement of cells in the S-phase. Described is an improved method for the detection of S-phase cell cycle progression base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0452a1e93fe1296350969c32b5dd19eb
https://pubmed.ncbi.nlm.nih.gov/18533904
https://pubmed.ncbi.nlm.nih.gov/18533904
Publikováno v:
SPIE Proceedings.
Described herein is an application of the copper(I)-catalyzed Huisgen [3+2] cycloaddition between azides and alkynes, or click chemistry, for the universal two-step detection of biological macromolecules. The first step involves the metabolic incorpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33132e1370df8547c934b7aa6c44d403
https://doi.org/10.1117/12.762175
https://doi.org/10.1117/12.762175