Zobrazeno 1 - 10
of 351
pro vyhledávání: '"Suzanne A. Eccles"'
Autor:
Kamolporn Amornsupak, Suyanee Thongchot, Chanida Thinyakul, Carol Box, Somaieh Hedayat, Peti Thuwajit, Suzanne A. Eccles, Chanitra Thuwajit
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background High-mobility group box 1 (HMGB1) is increased in breast cancer cells as the result of exposure to the secreted substances from cancer-associated fibroblasts and plays a crucial role in cancer progression and drug resistance. Its
Externí odkaz:
https://doaj.org/article/139c5936259b4f5799e4655e90bab2bb
Autor:
A. Elisa Pasqua, Swee Y. Sharp, Nicola E. A. Chessum, Angela Hayes, Loredana Pellegrino, Michael J. Tucker, Asadh Miah, Birgit Wilding, Lindsay E. Evans, Carl S. Rye, N. Yi Mok, Manjuan Liu, Alan T. Henley, Sharon Gowan, Emmanuel De Billy, Robert te Poele, Marissa Powers, Suzanne A. Eccles, Paul A. Clarke, Florence I. Raynaud, Paul Workman, Keith Jones, Matthew D. Cheeseman
Publikováno v:
Journal of Medicinal Chemistry. 66:5907-5936
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::719374538241e3474602d329b097d75c
https://doi.org/10.1021/acs.jmedchem.3c00156
https://doi.org/10.1021/acs.jmedchem.3c00156
Autor:
Jessica K.R. Boult, Gary Box, Maria Vinci, Lara Perryman, Suzanne A. Eccles, Chris Jones, Simon P. Robinson
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 9, Pp 684-694 (2017)
Vascular endothelial growth factor A (VEGF-A) is considered one of the most important factors in tumor angiogenesis, and consequently, a number of therapeutics have been developed to inhibit VEGF signaling. Therapeutic strategies to target brain mali
Externí odkaz:
https://doaj.org/article/e311da93a57e4dada4f26c73da4eee2a
Autor:
Spiros Linardopoulos, Suzanne A. Eccles, Swen Hoelder, Julian Blagg, Florence I. Raynaud, Rob L.M. van Montfort, Rosemary Burke, Harry Saville, Simone Filosto, Efthymia Theofani, Angela Hayes, Sébastien Naud, Isaac M. Westwood, Paolo Innocenti, Hannah L. Woodward, Katie Walsh, Konstantinos Drosopoulos, Amir Faisal, Mark D. Gurden, Grace Wing-Yan Mak, Simon J. Anderhub
Cellular activity of BOS172722
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025a4870ed10fb3bd66168054511b327
https://doi.org/10.1158/1535-7163.22505697
https://doi.org/10.1158/1535-7163.22505697
Autor:
Florence I. Raynaud, Johann S. de Bono, Paul Workman, Stan B. Kaye, Suzanne A. Eccles, Bart Vanhaesebroeck, Mika Derynck, Lori Friedman, Richard D. Baird, Alexis de Haven Brandon, Gary Box, Melanie Valenti, Alan T. Henley, Yasmin J. Asad, Joo Chew Ang, Rupinder Pandher, Joo Ern Ang
Metabolite changes that constitute the Venn diagram in Figure 2. Significant changes listed are reductions (labelled "-1") or increases (labelled "1") in concentrations relative to the relevant controls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35242fa0e3a742cbb6b034b2187e5495
https://doi.org/10.1158/1535-7163.22503601
https://doi.org/10.1158/1535-7163.22503601
Autor:
Chris Jones, Suzanne A. Eccles, Darren Hargrave, Francesco Hofmann, Florence I. Raynaud, Sebastien Jeay, Sharon Gowan, Sergey Popov, Alexa Jury, Vanessa Martins, Alexis de Haven Brandon, Melanie Valenti, Gary M. Box, Lara Perryman, Aleksandra Bielen
Pediatric glioblastoma (pGBM), although rare, is one of the leading causes of cancer-related deaths in children, with tumors essentially refractory to existing treatments. We have identified IGF1R to be a potential therapeutic target in pGBM due to g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::640aae47942f24340443cc8cc3e198f2
https://doi.org/10.1158/1535-7163.c.6535482
https://doi.org/10.1158/1535-7163.c.6535482
Autor:
Chris Jones, Suzanne A. Eccles, Darren Hargrave, Francesco Hofmann, Florence I. Raynaud, Sebastien Jeay, Sharon Gowan, Sergey Popov, Alexa Jury, Vanessa Martins, Alexis de Haven Brandon, Melanie Valenti, Gary M. Box, Lara Perryman, Aleksandra Bielen
Supplementary Figure 3 from Enhanced Efficacy of IGF1R Inhibition in Pediatric Glioblastoma by Combinatorial Targeting of PDGFRα/β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ea1a0d2375245f2f675778fbd807ca
https://doi.org/10.1158/1535-7163.22497045
https://doi.org/10.1158/1535-7163.22497045
Autor:
Spiros Linardopoulos, Louis Chesler, Suzanne A. Eccles, Florence I. Raynaud, Julian Blagg, Paul Workman, Simon P. Robinson, Yann Jamin, Sian Avery, Butrus Atrash, Chongbo Sun, Vassilios Bavetsias, Lynsey Vaughan, Amir Faisal
PDF file - 101K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8fb9ae57bfd3bcb6db1976abc0b02c
https://doi.org/10.1158/1535-7163.22496946.v1
https://doi.org/10.1158/1535-7163.22496946.v1
Autor:
Chris Jones, Suzanne A. Eccles, Darren Hargrave, Francesco Hofmann, Florence I. Raynaud, Sebastien Jeay, Sharon Gowan, Sergey Popov, Alexa Jury, Vanessa Martins, Alexis de Haven Brandon, Melanie Valenti, Gary M. Box, Lara Perryman, Aleksandra Bielen
Supplementary Figure 1 from Enhanced Efficacy of IGF1R Inhibition in Pediatric Glioblastoma by Combinatorial Targeting of PDGFRα/β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1e2e83c50e82bfdffe58fedf9bc1cf
https://doi.org/10.1158/1535-7163.22497051
https://doi.org/10.1158/1535-7163.22497051
Autor:
Florence I. Raynaud, Johann S. de Bono, Paul Workman, Stan B. Kaye, Suzanne A. Eccles, Bart Vanhaesebroeck, Mika Derynck, Lori Friedman, Richard D. Baird, Alexis de Haven Brandon, Gary Box, Melanie Valenti, Alan T. Henley, Yasmin J. Asad, Joo Chew Ang, Rupinder Pandher, Joo Ern Ang
Summary of baseline reproducibility of candidate plasma metabolite biomarkers (n=17 patients).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4f1e3fff57a56a184d3e834e92b978
https://doi.org/10.1158/1535-7163.22503598.v1
https://doi.org/10.1158/1535-7163.22503598.v1