Development of a standardized definition for clinically significant bleeding in the ASPirin in Reducing Events in the Elderly (ASPREE) trial

Autor: Karen L. Margolis, Suzanne E. Mahady, Mark R. Nelson, Diane G. Ives, Suzanne Satterfield, Carlene Britt, Saifuddin Ekram, Jessica Lockery, Erin C. Schwartz, Robyn L. Woods, John J. McNeil, Erica M. Wood

Publikováno v: Contemporary Clinical Trials Communications, Vol 11, Iss , Pp 30-36 (2018)

Background: Bleeding is the major risk of aspirin treatment, especially in the elderly. A consensus definition for clinically significant bleeding (CSB) in aspirin primary prevention trials is lacking in the literature. Methods: This paper details th

Externí odkaz: https://doaj.org/article/3cddc4d2299547b7a0db21362790e2a2

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Autor: M. Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M. Yerges-Armstrong, Wen-Chi Chou, Lisette Stolk, Gregory Livshits, Linda Broer, Toby Johnson, Daniel L. Koller, Zoltán Kutalik, Jian’an Luan, Ida Malkin, Janina S. Ried, Albert V. Smith, Gudmar Thorleifsson, Liesbeth Vandenput, Jing Hua Zhao, Weihua Zhang, Ali Aghdassi, Kristina Åkesson, Najaf Amin, Leslie J. Baier, Inês Barroso, David A. Bennett, Lars Bertram, Rainer Biffar, Murielle Bochud, Michael Boehnke, Ingrid B. Borecki, Aron S. Buchman, Liisa Byberg, Harry Campbell, Natalia Campos Obanda, Jane A. Cauley, Peggy M. Cawthon, Henna Cederberg, Zhao Chen, Nam H. Cho, Hyung Jin Choi, Melina Claussnitzer, Francis Collins, Steven R. Cummings, Philip L. De Jager, Ilja Demuth, Rosalie A. M. Dhonukshe-Rutten, Luda Diatchenko, Gudny Eiriksdottir, Anke W. Enneman, Mike Erdos, Johan G. Eriksson, Joel Eriksson, Karol Estrada, Daniel S. Evans, Mary F. Feitosa, Mao Fu, Melissa Garcia, Christian Gieger, Thomas Girke, Nicole L. Glazer, Harald Grallert, Jagvir Grewal, Bok-Ghee Han, Robert L. Hanson, Caroline Hayward, Albert Hofman, Eric P. Hoffman, Georg Homuth, Wen-Chi Hsueh, Monica J. Hubal, Alan Hubbard, Kim M. Huffman, Lise B. Husted, Thomas Illig, Erik Ingelsson, Till Ittermann, John-Olov Jansson, Joanne M. Jordan, Antti Jula, Magnus Karlsson, Kay-Tee Khaw, Tuomas O. Kilpeläinen, Norman Klopp, Jacqueline S. L. Kloth, Heikki A. Koistinen, William E. Kraus, Stephen Kritchevsky, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso, Jari Lahti, Thomas Lang, Bente L. Langdahl, Lenore J. Launer, Jong-Young Lee, Markus M. Lerch, Joshua R. Lewis, Lars Lind, Cecilia Lindgren, Yongmei Liu, Tian Liu, Youfang Liu, Östen Ljunggren, Mattias Lorentzon, Robert N. Luben, William Maixner, Fiona E. McGuigan, Carolina Medina-Gomez, Thomas Meitinger, Håkan Melhus, Dan Mellström, Simon Melov, Karl Michaëlsson, Braxton D. Mitchell, Andrew P. Morris, Leif Mosekilde, Anne Newman, Carrie M. Nielson, Jeffrey R. O’Connell, Ben A. Oostra, Eric S. Orwoll, Aarno Palotie, Stephen C. J. Parker, Munro Peacock, Markus Perola, Annette Peters, Ozren Polasek, Richard L. Prince, Katri Räikkönen, Stuart H. Ralston, Samuli Ripatti, John A. Robbins, Jerome I. Rotter, Igor Rudan, Veikko Salomaa, Suzanne Satterfield, Eric E. Schadt, Sabine Schipf, Laura Scott, Joban Sehmi, Jian Shen, Chan Soo Shin, Gunnar Sigurdsson, Shad Smith, Nicole Soranzo, Alena Stančáková, Elisabeth Steinhagen-Thiessen, Elizabeth A. Streeten, Unnur Styrkarsdottir, Karin M. A. Swart, Sian-Tsung Tan, Mark A. Tarnopolsky, Patricia Thompson, Cynthia A. Thomson, Unnur Thorsteinsdottir, Emmi Tikkanen, Gregory J. Tranah, Jaakko Tuomilehto, Natasja M. van Schoor, Arjun Verma, Peter Vollenweider, Henry Völzke, Jean Wactawski-Wende, Mark Walker, Michael N. Weedon, Ryan Welch, H.-Erich Wichmann, Elisabeth Widen, Frances M. K. Williams, James F. Wilson, Nicole C. Wright, Weijia Xie, Lei Yu, Yanhua Zhou, John C. Chambers, Angela Döring, Cornelia M. van Duijn, Michael J. Econs, Vilmundur Gudnason, Jaspal S. Kooner, Bruce M. Psaty, Timothy D. Spector, Kari Stefansson, Fernando Rivadeneira, André G. Uitterlinden, Nicholas J. Wareham, Vicky Ossowski, Dawn Waterworth, Ruth J. F. Loos, David Karasik, Tamara B. Harris, Claes Ohlsson, Douglas P. Kiel

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

Lean body mass is a highly heritable trait and is associated with various health conditions. Here, Kiel and colleagues perform a meta-analysis of genome-wide association studies for whole body lean body mass and find five novel genetic loci to be sig

Externí odkaz: https://doaj.org/article/c47ce1ff93954ef1b9d6bf1bf5948160

Disentangling the genetics of lean mass

Autor: Tuomas O. Kilpeläinen, Jacqueline S. L. Kloth, Nam H. Cho, Peter Vollenweider, Georg Homuth, Unnur Thorsteinsdottir, Nicole C. Wright, Wen-Chi Chou, Yongmei Liu, Kari Stefansson, Kim M. Huffman, Ida Malkin, Andrew P. Morris, Robert Luben, Shad B. Smith, Lei Yu, Joel Eriksson, Aarno Palotie, Veikko Salomaa, Michael J. Econs, Liesbeth Vandenput, Elizabeth A. Streeten, Albert Hofman, Elisabeth Widen, Emmi Tikkanen, Braxton D. Mitchell, Natasja M. van Schoor, Caroline Hayward, Liisa Byberg, Joanne M. Jordan, Bruce M. Psaty, Elisabeth Steinhagen-Thiessen, Magnus Karlsson, Harry Campbell, John C. Chambers, Fernando Rivadeneira, Johan G. Eriksson, Jari Lahti, Reiner Biffar, James F. Wilson, Luda Diatchenko, Jerome I. Rotter, Eric S. Orwoll, Launer J. Lenore, Cornelia M. van Duijn, Frances M K Williams, Munro Peacock, David A. Bennett, Annette Peters, Ali A. Aghdassi, Gudny Eiriksdottir, Weihua Zhang, Östen Ljunggren, Daniel L. Koller, Nicole Soranzo, Patricia A. Thompson, Jane A. Cauley, John A Robbins, Mattias Lorentzon, Igor Rudan, Thomas Illig, Claes Ohlsson, Ilja Demuth, Zoltán Kutalik, Aron S. Buchman, Jian'an Luan, Erik Ingelsson, Natalia Campos-Obando, Karol Estrada, Chan Soo Shin, Lisette Stolk, Gudmar Thorleifsson, Douglas P. Kiel, Michael N. Weedon, Lars Bertram, Fiona E. McGuigan, Ben A. Oostra, Thomas Meitinger, Mary F. Feitosa, Christian Gieger, Jean Wactawski-Wende, Yanhua Zhou, Serkalem Demissie, Najaf Amin, Anke W. Enneman, Håkan Melhus, Stuart H. Ralston, Johanna Kuusisto, Markku Laakso, Mark Walker, Tim D. Spector, Karl Michaëlsson, John-Olov Jansson, Richard L. Prince, Leif Mosekilde, Sabine Schipf, Carolina Medina-Gomez, Antti Jula, Carrie M. Nielson, Bente L. Langdahl, André G. Uitterlinden, Kay-Tee Khaw, Ruth J. F. Loos, Kristina Åkesson, Albert V. Smith, Tamara B. Harris, Cynthia A. Thomson, Karin M. A. Swart, Unnur Styrkarsdottir, Yi-Hsiang Hsu, Anne B. Newman, Murielle Bochud, M. Carola Zillikens, Alena Stančáková, Markus M. Lerch, Maria Nethander, Gregory Livshits, Dawn Waterworth, Christina M. Lill, Henry Völzke, Steven R. Cummings, Lise B. Husted, Cecilia M. Lindgren, Jaspal S. Kooner, Joshua R. Lewis, Katri Räikkönen, Linda Broer, Inês Barroso, Teemu Kuulasmaa, Jeffery R. O'Connell, Harald Grallert, William E. Kraus, Nicholas J. Wareham, Lars Lind, David Karasik, H-Erich Wichmann, Gregory J. Tranah, Mao Fu, Toby Johnson, Samuli Ripatti, Dan Mellström, Suzanne Satterfield, Jing Hua Zhao, Hyung Jin Choi, Vilmundur Gudnason, Lisette C. P. G. M. de Groot, Stephen B. Kritchevsky, Zhao Chen, Norman Klopp, Till Ittermann, Daniel S. Evans, Phillip L. De Jager, Ingrid B. Borecki, Laura M. Yerges-Armstrong, Peggy M. Cawthon, Thomas Lang, Markus Perola

Publikováno v: The American Journal of Clinical Nutrition
American Journal of Clinical Nutrition 109 (2019) 2
American Journal of Clinical Nutrition, 109(2), 276-287. American Society for Nutrition
American Journal of Clinical Nutrition, 276-287. American Society for Nutrition
STARTPAGE=276;ENDPAGE=287;ISSN=0002-9165;TITLE=American Journal of Clinical Nutrition
The American journal of clinical nutrition
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American Journal of Clinical Nutrition, vol. 109, no. 2, pp. 276-287 . https://doi.org/10.1093/ajcn/nqy272
Karasik, D, Zillikens, M C, Hsu, Y H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Swart, KMA, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chou, W C, Demuth, I, DIatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Chen, Z, Cho, N H, Choi, H J, Cummings, S R, de Groot, L C P G M, de Jager, P L, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C M, Lind, L, Lindgren, C M, Liu, Y, Livshits, G, Ljunggren, O, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gómez, C, Meitinger, T, Melhus, H, Mellstrom, D, Michaelsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Raikkonen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S, Soranzo, N, Spector, T D, Stancakova, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, NM, Vandenput, L, Vollenweider, P, Volzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', American Journal of Clinical Nutrition, pp. 276-287 .
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American Journal of Clinical Nutrition (AJCN) . https://doi.org/10.1093/ajcn/nqy272
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American journal of clinical nutrition, vol. 109, no. 2, pp. 276-287 . https://doi.org/10.1093/ajcn/nqy272
American Journal of Clinical Nutrition, 109(2), 276-278

Background: Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b768501bad6cfbb2327b96cc06a631
https://doi.org/10.1093/ajcn/nqy272

Hyperleptinemia, Adiposity, and Risk of Metabolic Syndrome in Older Adults

Autor: Suruchi Mishra, Tamara B. Harris, Trisha Hue, Iva Miljkovic, Suzanne Satterfield, Nathalie de Rekeneire, Mira Mehta, Nadine R. Sahyoun

Publikováno v: Journal of Nutrition and Metabolism, Vol 2013 (2013)

Background. Abdominal adiposity and serum leptin increase with age as does risk of metabolic syndrome. This study investigates the prospective association between leptin and metabolic syndrome risk in relation to adiposity and cytokines. Methods. The

Externí odkaz: https://doaj.org/article/6560dfc92a424c929d33157691b52b89

Development of a standardized definition for clinically significant bleeding in the ASPirin in Reducing Events in the Elderly (ASPREE) trial

Autor: Suzanne Satterfield, Erica M. Wood, Robyn L. Woods, Saifuddin Ekram, Suzanne E. Mahady, Carlene Britt, Mark Nelson, Diane G. Ives, Jessica E. Lockery, Erin C. Schwartz, Karen L. Margolis, John J McNeil

Publikováno v: Contemporary Clinical Trials Communications, Vol 11, Iss, Pp 30-36 (2018)
Contemporary Clinical Trials Communications

Background: Bleeding is the major risk of aspirin treatment, especially in the elderly. A consensus definition for clinically significant bleeding (CSB) in aspirin primary prevention trials is lacking in the literature. Methods: This paper details th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a27ba28d6af9ecd24d2fbb96ce619c
http://www.sciencedirect.com/science/article/pii/S2451865418300152