Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Suzana Tesanovic"'
Autor:
Michela Luciano, Helene Sieberer, Peter W. Krenn, Hieu-Hoa Dang, Julia Vetter, Theresa Neuper, Diana Amend, Constantin Blöchl, Christian X. Weichenberger, Anna Eglseer, Michael S. Unger, Ancuela Andosch, Philip Steiner, Daniel Neureiter, Renate Bauer, Laura Hummer, Suzana Tesanovic, Stephanie Binder, Dominik P. Elmer, Helen Strandt, Susanne Schaller, Dirk Strunk, Lisa Pleyer, Richard Greil, Stephan Winkler, Tanja N. Hartmann, Dirk Schmidt-Arras, Christian G. Huber, Fritz Aberger, Jutta Horejs-Hoeck
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Acute myeloid leukemia (AML) is characterized by the abnormal proliferation of myeloid precursor cells and presents significant challenges in treatment due to its heterogeneity. Recently, the NLRP3 inflammasome has emerged as a po
Externí odkaz:
https://doaj.org/article/4d77e7ab0fdf4883bc818ffc7dd4f0d8
Hedgehog/GLI signaling in hematopoietic development and acute myeloid leukemia—From bench to bedside
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
While the underlying genetic alterations and biology of acute myeloid leukemia (AML), an aggressive hematologic malignancy characterized by clonal expansion of undifferentiated myeloid cells, have been gradually unraveled in the last decades, transla
Externí odkaz:
https://doaj.org/article/f1a129f87983480cb3114ba7b413ae9d
Autor:
Julia C. Gutjahr, Elisabeth Bayer, Xiaobing Yu, Julia M. Laufer, Jan P. Höpner, Suzana Tesanovic, Andrea Härzschel, Georg Auer, Tanja Rieß, Astrid Salmhofer, Eva Szenes, Theresa Haslauer, Valerie Durand-Onayli, Andrea Ramspacher, Sandra P. Pennisi, Marc Artinger, Nadja Zaborsky, Alexandre Chigaev, Fritz Aberger, Daniel Neureiter, Lisa Pleyer, Daniel F. Legler, Veronique Orian-Rousseau, Richard Greil, Tanja N. Hartmann
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone marrow (BM). Here, we report
Externí odkaz:
https://doaj.org/article/9bf54160724d40848f05cabcbde9c7ee
Publikováno v:
Cancers, Vol 11, Iss 4, p 538 (2019)
The Hedgehog/Glioma-associated oncogene homolog (HH/GLI) signaling pathway regulates self-renewal of rare and highly malignant cancer stem cells (CSC), which have been shown to account for the initiation and maintenance of tumor growth as well as for
Externí odkaz:
https://doaj.org/article/af86c6e3071546afa3997891a84958f3
Autor:
Pleyer L, Luciano M, Helen Strandt, Daniel Neureiter, Susanne Schaller, Dirk Strunk, Rieser S, Theresa Neuper, Peter W. Krenn, Binder S, Constantin Blöchl, Zell L, Renate Bauer, Stephan M. Winkler, Fritz Aberger, Bergsleitner O, Dominik P. Elmer, Tanja Nicole Hartmann, Hieu-Hoa Dang, Christian G. Huber, Julia Vetter, Suzana Tesanovic, Urwanisch L, Jutta Horejs-Hoeck, Richard Greil
Aberrant activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome mediates numerous inflammatory diseases. Oncogenes can activate the NLRP3 inflammasome and thereby promote myeloproliferative neoplasia, suggesting a crucial role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ef20e68ff321a1c5f2b86bce4f71d0
https://doi.org/10.1101/2021.06.25.449862
https://doi.org/10.1101/2021.06.25.449862
Synergistic cross-talk of hedgehog and interleukin-6 signaling drives growth of basal cell carcinoma
Autor:
Christina Sternberg, Markus Eberl, Supreet Kaur, Florian Wolff, Hendrik Hache, Fritz Aberger, Wolfgang Gruber, Christoph Wierling, Sandra Grund, Josef Laimer, Dominik P. Elmer, Simone Roos, Hans Lehrach, Peter Petzelbauer, Manuela Stadler, Michaela Schlederer, Peter Lackner, Maria Kasper, Doris Mangelberger, Angela Risch, Lukas Kenner, Markus Wiederstein, Suzana Tesanovic, Richard Moriggl
Publikováno v:
International Journal of Cancer. 143:2943-2954
Persistent activation of hedgehog (HH)/GLI signaling accounts for the development of basal cell carcinoma (BCC), a very frequent nonmelanoma skin cancer with rising incidence. Targeting HH/GLI signaling by approved pathway inhibitors can provide sign
Autor:
Victoria Strobl, Georg Stockmaier, Suzana Tesanovic, Florian Wolff, Wolfgang Gruber, Fritz Aberger, David Licha, Roland Reischl, Sandra Grund-Groeschke, Angela Risch, Markus Wiederstein, Christina Sternberg, Jutta Horejs-Hoeck, Dominik P. Elmer, Anna Strobl, Richard Moriggl, Hieu-Hoa Dang, Christian G. Huber
Pharmacological targeting of Hedgehog (HH)/GLI has proven effective for certain blood, brain and skin cancers including basal cell carcinoma (BCC). However, limited response rates and the development of drug resistance call for improved anti-HH thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32448f1f2e19119eb91a0246f60b9ba
Autor:
Marc Artinger, Véronique Orian-Rousseau, Lisa Pleyer, Fritz Aberger, Suzana Tesanovic, Elisabeth Bayer, Daniel Neureiter, Andrea Härzschel, Valerie Durand-Onayli, Tanja Rieß, Jan Philip Höpner, Alexandre Chigaev, Georg Auer, Julia Christine Gutjahr, Nadja Zaborsky, Richard Greil, Daniel F. Legler, Julia M. Laufer, Sandra Pennisi, Astrid Salmhofer, Xiaobing Yu, Andrea Ramspacher, Tanja Nicole Hartmann, Theresa Haslauer, Eva Szenes
Publikováno v:
Haematologica, 106 (8), 2102-2113
Haematologica
Haematologica
Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone marrow (BM). Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bde17c88e6e52bc9f73a02d5ff2aa8
https://publikationen.bibliothek.kit.edu/1000127084
https://publikationen.bibliothek.kit.edu/1000127084
Synergistic cross-talk of hedgehog and interleukin-6 signaling drives growth of basal cell carcinoma
Autor:
Christina, Sternberg, Wolfgang, Gruber, Markus, Eberl, Suzana, Tesanovic, Manuela, Stadler, Dominik P, Elmer, Michaela, Schlederer, Sandra, Grund, Simone, Roos, Florian, Wolff, Supreet, Kaur, Doris, Mangelberger, Hans, Lehrach, Hendrik, Hache, Christoph, Wierling, Josef, Laimer, Peter, Lackner, Markus, Wiederstein, Maria, Kasper, Angela, Risch, Peter, Petzelbauer, Richard, Moriggl, Lukas, Kenner, Fritz, Aberger
Publikováno v:
International Journal of Cancer
Persistent activation of hedgehog (HH)/GLI signaling accounts for the development of basal cell carcinoma (BCC), a very frequent nonmelanoma skin cancer with rising incidence. Targeting HH/GLI signaling by approved pathway inhibitors can provide sign