New therapeutic target for pediatric anaplastic ependymoma control: study of anti-tumor activity by a Kunitz-type molecule, Amblyomin-X

Autor: Lorena Favaro Pavon, David Capper, Tatiana Tais Sibov, Silvia Regina Caminada de Toledo, Ulrich-W. Thomale, Jean Gabriel de Souza, Francisco Romero Cabral, Carolina Maria Berra, Marcos Devanir Silva da Costa, Jardel Mendonça Niçacio, Patrícia Alessandra Dastoli, Daniela Mara de Oliveira, Suzana M. F. Malheiros, Edgar Ferreira da Cruz, Jackeline Moraes Malheiros, Sérgio Mascarenhas de Oliveira, Nasjla Saba Silva, Antonio Sérgio Petrilli, Andrea Maria Cappellano, Milena Colò Brunialti, Reinaldo Salomão, Manoel A. de Paiva Neto, Ana Marisa Chudzinski-Tavassi, Sérgio Cavalheiro

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)

Abstract EPNs comprise a heterogeneous group of neuroepithelial tumors, accounting for about 10% of all intracranial tumors in children and up to 30% of brain tumors in those younger than 3 years. Actually, the pattern therapy for low-grade EPNs incl

Externí odkaz: https://doaj.org/article/384af2c64a0143f7b07d35ffbf8a2408

The immunohistochemical landscape of the VEGF family and its receptors in glioblastomas

Autor: Luciano Neder, Ludmila de Oliveira Koch, Suzana M. F. Malheiros, Luiz Victor Maia Loureiro, Donato Callegaro-Filho, João Norberto Stávale

Publikováno v: Surgical and Experimental Pathology, Vol 3, Iss 1, Pp 1-8 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Background Angiogenesis is one of the hallmarks of cancer. This complex mechanism of tumor progression provides tumors cells with essential nutrients. There have been a limited number of investigations of markers of angiogenesis in Glioblastomas (GBM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1176e3954137ba7d7a645b6d0c78ab
http://link.springer.com/article/10.1186/s42047-020-00060-5

Intravenous Grafts of Human Amniotic Fluid-Derived Stem Cells Reduce Behavioral Deficits in Experimental Ischemic Stroke

Autor: Ivone Farias Cunha, Jardel Nicacio Mendonça, Alberto Tannus, Luciana Cavalheiro Marti, Jackeline Moraes Malheiros, Silvia Regina Caminada de Toledo, Francisco Romero Cabral, Suzana M. F. Malheiros, Fernando Fernandes Paiva, Lorena Favaro Pavon, Nelma Bastos Bezerra Rego, D. M. Oliveira, Marcos Devanir Silva da Costa, Sérgio Mascarenhas de Oliveira, Sergio Cavalheiro, Antonio Fernandes Moron, Jean Gabriel de Souza, Tatiana Tais Sibov, Manoel Antonio de Paiva Neto, Edgar Ferreira da Cruz, Patricia Alessandra Dastoli

Publikováno v: Cell Transplantation, Vol 28 (2019)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cell Transplantation

Amniotic fluid has been investigated as new cell source for stem cells in the development of future cell-based transplantation. This study reports isolation of viable human amniotic fluid-derived stem cells, labeled with multimodal iron oxide nanopar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467efb7551e30e4825ce908b60cfb785
https://doi.org/10.1177/0963689719854342

Reproducibility of the NanoString 22-gene molecular subgroup assay for improved prognostic prediction of medulloblastoma

Autor: Betty Luu, Gisele Caravina de Almeida, Flavia E. Paula, Adriana Cruvinel Carloni, João Norberto Stávale, Michael D. Taylor, Luciano Neder, Leticia Ferro Leal, Marco Antonio de Oliveira, Suzana M. F. Malheiros, Bruna Minniti Mançano, Rui Manuel Reis, Adriane Feijó Evangelista, Fabiano Pinto Saggioro

Publikováno v: Neuropathology. 38:475-483

Medulloblastoma is the most frequent malignant brain tumor in children. Four medulloblastoma molecular subgroups, MBSHH , MBWNT , MBGRP3 and MBGRP4 , have been identified by integrated high-throughput platforms. Recently, a 22-gene panel NanoString-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e0353f39f481cb7585d888d0f059bd7
https://doi.org/10.1111/neup.12508

Lack of KBTBD4 Mutations in Molecularly Classified Brazilian Medulloblastomas

Autor: Luciano Neder, Rui Manuel Reis, Nathália C. Campanella, Matheus Lima, Marcus Matsushita, Leticia Ferro Leal, João Norberto Stávale, Rodrigo de Oliveira Cavagna, Suzana M. F. Malheiros, Fabiano Pinto Saggioro, Glaucia N. M. Hajj, Bruna Minniti Mançano, Gisele Caravina de Almeida, Carlos Roberto Almeida Junior

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Medulloblastoma is the most frequent malignant brain tumor in children, representing 20% of all childhood brain tumors. Currently, medulloblastomas are molecularly classified in 4 subgroups that are associated with distinctive clinicopathological fea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9be10710f632df0b343834e24d07d1
https://doi.org/10.1093/jnen/nlz066